{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022rOyeolLPFkuqG6bZzvpydKlfCjtCBeyL3sIYCAKA9WmfPEetRrw9kLwzW1XiEnZ30fi57e9MNc6\\\\\\\\\\\\\\\/ADX9GrO9bxFkwsHHUlsWGi3NsqWfrmijvF\\\\\\\\\\\\\\\/a1cBf8DZTOGmb8W8v1bwPed04mu7zXOAk1GQg+MEtXhMS6uBsYSZxOePTwpf9iaPwkvoifc8CB91qll0tebmCcPrNyenrPKFCaWuwNVTg63UhFyWaSMHREOTsjzjcXRQZ6LMF+3pJXO11u1309Ppg24M\\\\\\\\\\\\\\\/tW7xiI2uGe+5vwcdLe08WQsbU+rIL2KzAv4nRn0Hny\\\\\\\\\\\\\\\/muvy9a7Vhm3HcitD70bhbw0LzW7MZ4epEBr3PG40JnNxatpVzlnQyBDHYg0g0bjFbxQxo97R+ag6JfarlwhyowpNV0Hfr54p4NkdlrJN8+qN7AnecLRifvwjAtU6KIiugZqMdF5g+qYjVzs\\\\\\\\\\\\\\\/548dE4G+gbt5cf4AuDV2eZluTL9YpoDvonlVj5jLJok65Nd8uYLfciK5qhHMEF1v3mxCoE6R0ULTuFXh2s+H3smMCa6I8U1hQCVs6r\\\\\\\\\\\\\\\/tTD1dUCZQw58\\\\\\\\\\\\\\\/vegyMCPvC65hGcnwHwk+2RN8c\\\\\\\\\\\\\\\/FwpS07yJwTKoBPRIw+wcxRP5bc+hy1gSTikBrpGj7MUNG01OmqzBZNL3yFsnpwxEV8ozUOXLuz9Aq0MMG1GAvQ+HqWIuKWPOsyenNux4YTCszDC4j6x5oIB\\\\\\\\\\\\\\\/1MuB\\\\\\\\\\\\\\\/+6aK8jNGgBWLCKI4vOGWHfFoPtQgLS3Ato1FUl\\\\\\\\\\\\\\\/JehCpknSfe9Vl9lp3TYL7yYVRk5QMmMNv8N9UHgZI26+zeU\\\\\\\\\\\\\\\/vWZhVV7Z9\\\\\\\\\\\\\\\/oJNCvMa5RLmb5RCN8ISbSJX2dOgHl1WA7pShv0DR9mRRIadhWgBybg1x4CYUTrwLDfBXSeY\\\\\\\\\\\\\\\/GIQ01JxamXS7LK9lM9J5\\\\\\\\\\\\\\\/CR5nUUpDtzgLrgVFhbk5ldANSCrG8Lugpt0CPP0NPMNZWypRbbqRHSy1pniRkFwuFKgGo7sham7Vqk3CLgpGhT9JMaTFqleJXLiijDVlkLdBbknJ4NRTN0v8G1uKrAy4BaJoaNVfMVWYleAf2ADzIIj3W69KM6HjxUQUr9OAtn109UkVk697Yr8QPxGGgbTuPa1IiZS8tl6WwwGsVpfiRCAAoLwA3JXUUSKi4W160nHNg8fuGJ2bQ4aamqLfQ5uwywKAbxJouWXGHxqWk1qvRbH9FL+lrELbUbtqlkL8txtKz0Fv4J7vSMCshhaRenvjVm+u53YeOGijcmQhUGhH3xRw5XKhnOotEJm7fjRjfdBW8P+jjP\\\\\\\\\\\\\\\/QUZi4JL8KExz+cy\\\\\\\\\\\\\\\/kaUHpc5Ng\\\\\\\\\\\\\\\/aHq1XaJKTp0BDRimVfR\\\\\\\\\\\\\\\/Z+Ig2NCFvWHFID\\\\\\\\\\\\\\\/8htGnqWfpiAMmN9COZD99BxW3fkIinbp0ZE0RMzIxnzbh2ZlgnobmNr8nQfQKqqsZ5i3uJS5t+Seum5DF\\\\\\\\\\\\\\\/fgIe8W2AKyRgFUFK7rHr7nZnwGpmYoQN9YjGu69Lhdu0\\\\\\\\\\\\\\\/PqcuqQuJ5X0Ya06cYJz+X7vGQ9ezHq5f0Le8y04IndjH4a3T24wbtJinI3o0\\\\\\\\\\\\\\\/y9qM37mKV9pHWL0xbagszLxCynSYtCvnAh62\\\\\\\\\\\\\\\/LJRnEle8SD7Uxd6vkrDhbOl0M2gVEvkY8MmMXtbiNhn5oM\\\\\\\\\\\\\\\/7Icf\\\\\\\\\\\\\\\/ulsYMrI6M88KNBPzMXP68YFY2p6PU4jyCdC+owSGDTIeadHtJ3bQptbK0GN03Z61LQypauR3zZqV6SfCGki4NhkUvylSQB2VPxkhjqMROUDICOCN9ITrY1T+4Ppi3HOvw02vprtRusHJ2fqBDOi1G8RkqHHBx0i1p1U8J8vveOgMvN6DgQId\\\\\\\\\\\\\\\/C5dHrMk19Mrsm9FhTiWRcCi1yjPze70mkBxWLWMEloPgcdSjCNkCqM+A7zY2+v82S5GLo\\\\\\\\\\\\\\\/TfR4mAn6BijXe6Kj1mY6DsgKwmylSwnHFB\\\\\\\\\\\\\\\/Dmk6YKmB5kUhv3jbyTUIm\\\\\\\\\\\\\\\/xLJ4kGn9SgRHBoDoyvgC+r1S+iy2zXvxHdvT20hl26YyvIGmxjGOOO8JLYTSDLVrcvwO+3+s2QagJeEZ4CpcwnKr\\\\\\\\\\\\\\\/AciAq0maOyJJcrpigcwCrkxwzdS\\\\\\\\\\\\\\\/KdvxFUvLwL0X6+XU\\\\\\\\\\\\\\\/8JYaHyGQ9fgr\\\\\\\\\\\\\\\/9DMcRyPKbXG2RPownZIN4WqBiu5IsRn15MrVvYT41Q95hmfrJy9DUIhwyT7qbrYoGuAg6dIDcgorXbtqtuWtFNSoBU\\\\\\\\\\\\\\\/W\\\\\\\\\\\\\\\/waRYt8SMzAvPUK37ZQb31IOcl8Kv4WGk8kPTKGfSR0wJg1nauFyhKjnaNupKvwd+6NPsNMYSp1bteog6O+kRWXrxTCt4UznoW9jC7H6+eaKCsv7H1fCe0KK78lJQ\\\\\\\\\\\\\\\/wkXGbSX+YwemKujBrLDMzxUkqychJrgJrfQtqPX\\\\\\\\\\\\\\\/JLYFRGWM8mkyQB55upReVMIBIR64YNeEnTUjvwlkBYA0XJj7Hvk2wrd\\\\\\\\\\\\\\\/H7GsedIYipmtOnw4LlYZa9vMtvBIZd2nAFY327BQ3eIQ5Oitn7+J215MAIZiFqcdukG6L3pb\\\\\\\\\\\\\\\/Dg8WBLJy33+Ias1T6Jm8uXlJFtudn2vEnOiC7nB6HN2lPPRZikp3IWHsCEO+ld6p+WD+wdIngYhmHRc7oswQKXxh6OK\\\\\\\\\\\\\\\/FVpZGJ2G6PE1h7eZXT\\\\\\\\\\\\\\\/Z919oHCGB0csWrwoJbMJ\\\\\\\\\\\\\\\/msRiJ4c1GtP0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022UwuPMAL1wOuE2CmHiqruEw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d7aa668a0c07d105693405944a9530dd24a82f94ac3d7e657cdbff9536a450ca\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A476.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A476.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0797\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0797\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0797\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}