{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022d9QlZ5MYwNVTbdpQNc4U+Dfsfv8ii79c6ogdTtkLMbOzgHC7dZYhk1OCgFxTqOftOIwqJgECGAKeQT9n2\\\\\\\\\\\\\\\/FqLaGReHwEPBMh4a7RnyGaOpnk6eRLNVTm+pb\\\\\\\\\\\\\\\/7XghyhreYoyiJ4yhSUhiM29\\\\\\\\\\\\\\\/xTsxknpoxBV7n9bhwumy6sci+zuBSjyxzkJ0rY1sxWitmsTKf0FfE2h97BDiUOVtlkFvTR2e\\\\\\\\\\\\\\\/cArHONPLc\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/rm0NwwiDvibodD0L4q4ifuXTppzEC9JDeSaFC2TjNm4Utz4qwbCQondEmbwsPQEnjl3IkcCknsVGJA5Q1iqb48GvjkLdBjbaAxoQruqa6kNld9BQhqd1s410wY3QIEkb+G1Jc87era4mS3TZU4RKJLwkJq9KOI8XRmf9cxvWEl\\\\\\\\\\\\\\\/qnzlgCyhm+zPEIsYMZoIIylcfY7OztnBsYEfw2\\\\\\\\\\\\\\\/qTi3iGSz6Tg5aIJH6dkl\\\\\\\\\\\\\\\/rar9yCDtKcII1yKK7pad4TY+OfebLtXtBIImNJgN+tTrm2DHQsGQV8NL\\\\\\\\\\\\\\\/AZB9BUQRC+lUt\\\\\\\\\\\\\\\/R0sfCq4gfVFtey6DPE2HG0jr6PJRnmTaWkwO7ans0unbq8GZGr4g7ZCVKPJENaG3jOx4nwP87o3qAhSLx9WQCaBgGUkfJ4mDs14FYZinCVK0zgHMZb5goRlvgesquZkkayLG9eqTDARMu2gL66tYkxscJaLotifRt2dBJr7L5ICQgbWHT9+sS\\\\\\\\\\\\\\\/B57Mo9sf3UVldrdc5IlB1wkydvJlUdlLu8yawDJgy8lpjcTnwGbEpCVfHRU4NnM4Hy0THyGwDPEqZ1Zfrp8lM9O9oAKXgdCJ7EoxhceT8wCVvWfXr2fnG5O7oRObGqJXhGVAuXAutwjFR9MJR2ZyQfBPu0KPtHIHY7UOSxTTvlXaweY4RNq3Vel5YjfW5wppBvPQUlWr6B5\\\\\\\\\\\\\\\/TyjlErzMeujEr3U+vrCp9c2+w4wey7sBuKgAwW03ajXgXVWbjbYYJiwJkV7h\\\\\\\\\\\\\\\/hGkMWTguOkTy2kjkPuCibbn0Ki2uUpyLgJb9yUfBLmQZY1elWf7vfSQNNTmn+jIprelsmZGhI8G5lIyCpcW91oUZoFBAc8zbjRtdLNF3V8fparFXQaYtDnESvJd9cIrhiu6Ppxy89cavUjXg73WqGCs9E2HLy8vZ86Gg4l+jF+1JMbGHEUr+TBGfH2DK5I47aDnSNd98DtVeBywoh7yICi977z+qxzpVo\\\\\\\\\\\\\\\/GIrCnwa32jIyLW8g5USU0F3Pi40\\\\\\\\\\\\\\\/fY75QwkvQtupnCMA1zxmaN6ZKbr1GIRlX\\\\\\\\\\\\\\\/mKyaxzvXH814usin6hRGCyPIwunqT1vF+0j3FE9OnSS\\\\\\\\\\\\\\\/0pvTfNKH561laYQnnWV1qwxgJJV9CPva+NRx+gAyNj0oWUWHJUSd6iFyqCiVnXU\\\\\\\\\\\\\\\/li3gSGZPyQ2L0t13ok\\\\\\\\\\\\\\\/jDAgIAqQ+1PwXdbf\\\\\\\\\\\\\\\/63XScvyeEtzYgOTbjZ5Y7f35MESmoguIhusXA7YwSvMloyWkz6uZFZpiY\\\\\\\\\\\\\\\/2pxkwacbJXLRM\\\\\\\\\\\\\\\/8\\\\\\\\\\\\\\\/y5qqvGAWxCyTszzrAxGpmGvCJcpRTiKeMDjmqxU6LZvtfPOb13DIf8h0ePSuawUor8KVw1UcAJOjpmiK38MhHJg23s83D2U7VGT3WAp5BFNyxj8Ha0d6vq2xcQRjP6\\\\\\\\\\\\\\\/nfooSOtGRMIbrZCb7Nj3fySdjXmVmdT6sxPUZnXFwtpBXFX148AUW0hwVWg2QUc6+3Q8YpYhHFYztGCK4b9mTaE1e9JMnNCg++MqQyraJRUxj9oHFgm3zj0WDRSsKRqs1N0D96j\\\\\\\\\\\\\\\/YRZzd+qbTvwXN\\\\\\\\\\\\\\\/8Quz3BZyJYsLaNKBFsoHIgEzArguHP0nEb7dtMH5NUguNcBYafYeuTC\\\\\\\\\\\\\\\/7ThgwPPTDAJoMVVaDn6YuobhysFCxTZOiYomz4Va8ykZD+43htKPpUrcMf03YfBxtGJ0Y6EJiFobdTADNS8kOvFY0cYm6wyPzXK9X6v898FW0Ag0FteFvv7N9Ozk2kK\\\\\\\\\\\\\\\/R51\\\\\\\\\\\\\\\/a7Oo6RTwtAmS37lxHCqDbpB90zY7zPj2xscwYGqBRa7UbnMR9eQVZRe6SCxq40udazkoBHTtrdMpW2GC8OieTfOXG59nWczV+wSXCJ+gFKHEikYgkTmcwVYjXSw8bXgwnTDQfuwGwtLANhDRJrpfNlWW0S9d1fre+U+fU3NW2mTZaBU4QVIVpzCbTlTZUhxR5Wnh4Qe4Zyn\\\\\\\\\\\\\\\/s\\\\\\\\\\\\\\\/3REVnLxiDZkm4szVKBzmgcsu8f9WlZ+sSWa7N4vO\\\\\\\\\\\\\\\/WceDCAEd6DgEqU2a8pn4AJmAFAKRX\\\\\\\\\\\\\\\/gmce8zOSPf6YWDzgBxZt9pcEVpXP1uNtnkyiFQyujxJ0EzT18SDxmLk4Xyv0VbxWnndbFN7NQA3uqiRbqPYRbHpHE\\\\\\\\\\\\\\\/dQoh42+wm3qPrnUTvhoCzuFjtCCNWb9\\\\\\\\\\\\\\\/PiyUvYUK765sOlmdRnxvSRzbQ62JnWpl3Fbduipx3565J1Kwm97NXrIugvNOwW2RoUt7tfs77mV1hMOPMoH9AfZTAIT6xGm\\\\\\\\\\\\\\\/sX05lUar6vnrUJHiP2QUAFKegvP\\\\\\\\\\\\\\\/rfIMy6s\\\\\\\\\\\\\\\/pFTM+xS2pn5r1aDQ9+mxPgoXPRRSLsLNyw3qJistA\\\\\\\\\\\\\\\/1HN0WhtUbqccvX38tM3M3LSed802kWjzpK30a9KWYWuc1iQPKRmNW9ZtD2ekQN2sO7oy3mDTZlI5Vi\\\\\\\\\\\\\\\/1P8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022DMU3dfy8gXpaABYi4eS+ww==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002214536154dc0cea03cb5e1f768b87763a7b44f8a6b0fabd5d3791f7e7d5cb1c9f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A352.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A352.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0588\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0588\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0588\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}