{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022bPaA4rEcXwfMoViTwVS0GsEZVBZ3jo6mx\\\\\\\\\\\\\\\/4bht\\\\\\\\\\\\\\\/BqvrRnVdwefJGMlUfTzxF0O\\\\\\\\\\\\\\\/L6jw0cxV9ngeLuZo7ePooMnB+3+z\\\\\\\\\\\\\\\/j0t5cPszaPLEqPyfrEDE6ky\\\\\\\\\\\\\\\/KfgXi7lRj+jovMKrLh2bnS2Gxtdfr6a7S4JwAjp8ykTQQAKOz2RYmZ3OzkaNUJiYzJ+fexBbYH0u8lHNalalgccJC8xTcz5mgzYSSvxtKKAD69\\\\\\\\\\\\\\\/5gcTBM6rixImsAZmnA66v4o0Dlyuw+jp+xHJ5i7Lb0LBwjXTMav2SFs3HOw2o\\\\\\\\\\\\\\\/zQQ4BMndNRl0euDoWp0NLGxGDkWxHWBrwsyJvBj5t+2Cz66rVdAqvhDFsJ+iirbJhUTNu33Pfrd3z9RWo1U2jwyQ+ajuuK1NfwA4VKdWs35qSxK0O6ANFIZYuJlDFElp+ITynkJfH0PrwElDt0WkAMdPsTzRHVyV7vzsxpqPv0xZF4P+mgU84Y37BN6c62ekRNN1L\\\\\\\\\\\\\\\/fSmsFVxwgikQhy1sJrmD6GKdfl6\\\\\\\\\\\\\\\/XEIkf7QKbzRKzxMJpHSTb\\\\\\\\\\\\\\\/sJSIPTafRQSSCgRHksvQo7VsQ+mT75heN8r02VUQMwUbAU\\\\\\\\\\\\\\\/6fO6FJeb12Jzk9k604Ch4dlSwc2PoVyoE8BIiLlve\\\\\\\\\\\\\\\/81hzAsOR6HXc+vHYFNzqrbm0i2P52swl09tOUzH3A411yjSl2ZBJoLAAE6FpOuIYpZd2MjdkFhbTyEA\\\\\\\\\\\\\\\/ePyQla2oCpw9RM19WGawqLjT7LkygI1xokofaiVsC+biNKklcWhkV5v\\\\\\\\\\\\\\\/oAI6VJeHYQMoAFFY44UqhnvEWqg4mgVpT2K9Z5CTYACponmFfISuHcXFI9YEWVGQ9c+jW9gRNC9jmgXsIYhl7MH04676tXCICMpaiSI9xJRunlYQyi\\\\\\\\\\\\\\\/iMQKgU8+ZacV3+ioC3L0IKn4xJYRHeyJJDSJhEqiK4nfLEB+rN0YWxTF6xYQfhZyj5qjsbQ7rsSYRH5RjxB4XRlZkKJR\\\\\\\\\\\\\\\/VqghCOF7sidppSCx9MkgOuPEjyRd\\\\\\\\\\\\\\\/w6DsY83rLPhH0W93VQQN8MmZU\\\\\\\\\\\\\\\/zFbaC3OIckn4XNSRfXUg3W17Bku8NC46mYIkMVLhKXenXby9DKYcBaRJb8svx8bqK4DXcGflj4XemhauNaYY7oO8vP+CEgLzAxUUjTunOPYQD4eWcbwG+pwuXTfMDuWTOsSImBDTr5XoTNedrPqmRV\\\\\\\\\\\\\\\/3OuNoIvGTdPHW9e8Ew38cyXyYOGNGcdd+plaahKKOC1xjcslzGW5f1dEocfxVpFHAhiRj56iHwRET2SJFd0F8oEfkSCmN9+R1O+\\\\\\\\\\\\\\\/50vWrp8iT290CvYGDCyIetUT4GPq4qW6z+49FO6lW0M\\\\\\\\\\\\\\\/sKFb8M9e1MU5NyJu+OMsX6OKBPAKttQ9diU9A5qhBv+ZOdBSYdkVI5XMlOmEe3QGhePOMkgos\\\\\\\\\\\\\\\/agaCSjkldM3NICdYnFw5waE4DGunbk8w+p+KDN+H3BRmTo2ZucNLukpkzLDTylDekPhY4g1RYXejn9GtHqGZN977wDVST2IzQPYwUYyW1ZdEgmGC7x9QthE9rzJVAd92j+mVxvHotLfQ41hJ0JRddi01Yc\\\\\\\\\\\\\\\/JXrqCltImc\\\\\\\\\\\\\\\/pwCAY7rkAeNgCqFrn3snu5MUgtTNIz+kwo2Lqy1ji25f9HI7cMF6yiaX+fKiI+8HDbg\\\\\\\\\\\\\\\/pE4tsS8THUaakL1TLQQHPNAq0pbTVWsp0XplFcA2L\\\\\\\\\\\\\\\/VVh2w1mnKb5JKmkX6xdN12ny\\\\\\\\\\\\\\\/k4vGcIFpJKCGjLFH3huuLpt6g9pyujTKnAhiMup+DLOA6pkcz4HiRl7oVEf4GIeQYSJLyh9usNleCmj9eTcArVF8ou9OwTf7JnUWIj+UETA492zor88j6nQt7E7z2s34JwxvifViph23M\\\\\\\\\\\\\\\/rj\\\\\\\\\\\\\\\/qX\\\\\\\\\\\\\\\/Lbi23+GzZWeNcxBqty8ZydeQcV+NP7mb9h2ZtuD5sPJFV7HNksuI\\\\\\\\\\\\\\\/bl\\\\\\\\\\\\\\\/e1nXHO\\\\\\\\\\\\\\\/Nxa\\\\\\\\\\\\\\\/wxJ65TyAEV+X8gPbeHJGA8jq5B8DIi4kyq7Z9MOzGKR8kptswMsUPv3pIiUh1A5jMdAe6jmihMmo6Ofwetm9jtwNlZw50oullMJft7qpOJHpjc44MDQJL4bdotCRfdrmNB\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/OLgC7GCbST3lvywwS7LOH63CUe3L038D4MuramizrqeFAR4fmZ3CEjcWDLDV53DJU08BIA7snTtY29zYJcBKxSo41zzmS4HydLdVIBMvBL0sIAycTZ6Nk3NCMuD+h8PAAqiiV9r7nthtMETUXaZRI2sUIkA\\\\\\\\\\\\\\\/hLI1w3b6\\\\\\\\\\\\\\\/5V4VprZDeJT8S9JHXurlmgxZBpq4DzDPbqdHB9kB4DM5yBpudR7TgMXghg7KpBCTVEfoePjdX4kbMXSiKuysHjKPvCfT07zinWrOj518Df3S8hB4hHAwOXQAeqIptr+z0qR1Q1sFfOEuJJyAvwWxORthvzWorJdbfB\\\\\\\\\\\\\\\/dgPnovilsfTn+oR8lhe3+yGPTOb9h6VMhEJ0M7idnd+Z9z+ZCrYnDeAZLuo0TpjYws\\\\\\\\\\\\\\\/LzQJM\\\\\\\\\\\\\\\/mBY7boPzP1ggvnCLbnr0s\\\\\\\\\\\\\\\/av5czlCTfiHsdy+wW3LuULKF7jf8\\\\\\\\\\\\\\\/KiD0zBg+32n4pEBNje6AHEPrUAXQdQVaeXvqv4fw8J\\\\\\\\\\\\\\\/9eaag1rC4wtB3Z3VrY5wed1MKur0Dix9cHD3YvE2naj\\\\\\\\\\\\\\\/Abez3hGbmyI6980WxGOcHc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022cY0ewSM02uksvefBYu36ZQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022723d651743e92fd83b6b82332bcac5f40c170c5d6ff17b74a0e22fa8ff7b2dec\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A356.3.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A356.3.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0596\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0596\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0596\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}