{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022HBBdZWUAjefFNQNTZ3O0Jg3BnF7QOe\\\\\\\\\\\\\\\/4ANKebi4jZ5Xlx7DmtJLrL7Wzv8El2wRfaxix9UhApKF3kr\\\\\\\\\\\\\\\/zkMkajtcoB8lEopdj\\\\\\\\\\\\\\\/XI3Hx0VPTW7rBRSVOLQJNcG\\\\\\\\\\\\\\\/g0bvajA2ExshGRMH0WK3qC102KPVQ++zPsa\\\\\\\\\\\\\\\/8okwgZKQJ+mCSpJnjHUXR3QfcgS63mBIutho+9R1enppigC20V0TK+ch446oQU2opHedHa7zQoXJ9rrPNZ1A3aebPmhLUh3vWIvh0ADL5A6rqLpdCsqBazhiiWhGuim6U4FLC8I0V6184AMlNXg27p+Dl4y2cpEqyim\\\\\\\\\\\\\\\/KX+bdZUXZpF8QhZ5\\\\\\\\\\\\\\\/EnlUvO8dXLGksi6nwyM57szLuololki4KTgpbTiTL\\\\\\\\\\\\\\\/p99QXT\\\\\\\\\\\\\\\/SQcdXQIHnZYNpr4SSmuHa5FIelRPtzijhbLA8ruGBQN8QcKkcpGKcCBhx5exaZLq+SSsqwWtsyc9jl6jmGYMNg037nNwpfy7cPbmzzudaFiHyqpboCrXUXDXo3WTavzA1nu\\\\\\\\\\\\\\\/efrHWVL6wvliYBrxb8vG7foCuEySf3CK8ZCYGVgaalX6r6w9f8E5rLPKIXFsvyd7YVGGwjIOlwnQND3Ra5s+ogg+2DEwUiKiNoVzpJ+cDTIud7PVta\\\\\\\\\\\\\\\/5YzqemPPsyme5lJWDgzzWJBlc8UNs25mX73bGms8FZGJ5QJEoKB7oengVysPwT5\\\\\\\\\\\\\\\/6FFl7uTv+I2KlsmuXwYoylWAfM1qNLiZNdVYpieJIDAHIPDcBTfnzqXMI3gdwFilOx8RlP7DPiU1AblC5bAxUXz25pKVoAtwWxMzdu+c72bLZJxqY\\\\\\\\\\\\\\\/CoKUSSDvLvujm5Xq65mT7pPYnJIT9RJ9jfDBIQUucMfPA0IClOUyQj4eqpVo3t67JwMGNwW1ugmNUFrdKVFtTL1CqLGW3+BoVclZRNdsqOs5kyQFgeh8\\\\\\\\\\\\\\\/AnX09g75Ge0YfFmJYsuEI1nxxkUuJFT9FYREPWODOq0\\\\\\\\\\\\\\\/m7RzCRQLpibRIhnD\\\\\\\\\\\\\\\/YW5nBkc6J3\\\\\\\\\\\\\\\/Nehdl4ST5LA1vbY0DPAGD1XyXBbikuAVsHLyC5wACGVnaW7R5mFD6LugNbDm2Q6Ac6KuGGwDiOYOCksNLFB8q0tm5d1pU1J4Bef6V8zEQUGjUIOT2Qc77UqKMa1oQApqTnoAaWSUbrk9chUL705Ox7bGGVATeho7\\\\\\\\\\\\\\\/C0DVMcBC+lqb5+utbyJ23AoIw80\\\\\\\\\\\\\\\/NLxMIgXJBJIDOZd\\\\\\\\\\\\\\\/WXgdDyEqJ7MJM0EPuQT2Ap0hXQaQLm4xZRzXhDJBysbVbCbmteeoRZT7cz5SBwQRb4Sc1wPwIqrI8ustwR3UcBv8kjqi1phyYNbMowj+zsbKJ9kSzWFKX1y8e5lj3ZxRi+1V+GTR3OkNEYJFn5HYVRaAYo55DaYmiyobQ+Z16ToSq2xo5AKOTnGcLm+nS3vSfFQ70TY45H4ce3yJdDA6cnrf94XmApydp9ilmnRdImjbmcuWkB7bZNUVaKDvbUpTQwo894S8ZntwlZGqwph0FYOIcxTkPe8t2ehfFUnfPTEaD5WdGz\\\\\\\\\\\\\\\/VVdwKVD9sp7fubdDDqb8eYW7DnjordGMwQ+iidgzXQRspUB5We\\\\\\\\\\\\\\\/HfluMPsroITJFqWp\\\\\\\\\\\\\\\/ImUT8rCmWfehyShmQJ06FW\\\\\\\\\\\\\\\/nxapI9i0HKYvDMWmVDyPqnfnkPBZIiLR5ej2bxD16SeasAWqaVuycIWqb0CMB7rXC4gTwkXkIQ0aJLPhfStBFfACgLCKz9RjKYQou\\\\\\\\\\\\\\\/cWxgq3Z\\\\\\\\\\\\\\\/vb7Y9qLfauZ6Ukt36La89da8L3DsXe0\\\\\\\\\\\\\\\/eRayc5JdDnTHAAFmPYHtcVTgSMYe3jBAJCJLP0zurASjSbUvBfbDFjiCWA+S7SMh0Qm4OK0gb3MtAEIaZ0scvmXKN3K2oLqz7OWIxmVO2cHsxxsdL1BnL8nPdS0dGLrL5WKgmqXiviLQhgWZM7Cq0YLanUuLHd+oz3JV8i8xo2wUO2XXrJPO7257Df4h5R0TZ1feJ3bvQ0YABjShwbZnno2AVUPusf7sdqgX6H4VQASvVevAxO9a58vOmaYxgX3WEVWJsSjVdvAlxcQzOkiIqymLWFr9a7x0Ni0XrN55YDAQt0F+VM3kBIHMaz\\\\\\\\\\\\\\\/9If+XswY\\\\\\\\\\\\\\\/Fr\\\\\\\\\\\\\\\/fYRIluWlwFCvQ5xjVAi89XikeRyg3p1Aikt8m5OHjO0u0QF0hZrMFaM2H0ktLooesrWftL4IjP3YloeJ2xEvKuS6H\\\\\\\\\\\\\\\/m26dIjziAqjYaXiUvicd6hcjXY5EKMJgZNgIDqI6D4pTNB5FRhDOoJeHHqGGZzB6K3LOFrZrySMnxKEY1J1mwTU4ySkQn59BJqbmB\\\\\\\\\\\\\\\/CzVzs6C\\\\\\\\\\\\\\\/uu4NV+u5FoCYb6fiwCuT5YwDibQMY+G\\\\\\\\\\\\\\\/rJl1vivC4EqP3n1ODtwelqYT4fjfEp88Cf3DPitg46S4fvbuB9+M3JVYwhpy84Q72jw4alqdYJ3V6WxYZ76ZJeK0y2BeyizJ6xqHx3S4h6E4+2wabj3oER2iXVIZA1gNxK6+bqQ5W30DhT9OtYQDOnVSVPThsbVjUtoPD0laSN4SfxEiSOjqTqe1BUIT36k5ab1yv6sZXmHWYN8JCsbyr1Kp\\\\\\\\\\\\\\\/lavz3ycLcM+eGL6jaTqTZQOfSTZZcnARdTur994cPb8G96cavWUfOz0\\\\\\\\\\\\\\\/VG0DKW+dJa4ccCLSSsH7a6Pkk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022V+FUDzX89\\\\\\\\\\\\\\\/s8YN+XBpp9HA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022ed030f5cb717e8c0e55da7645e71ae5a958aefef6c4450edbcfb1ab69c8b2efa\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A375.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A375.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0625\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0625\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0625\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}