{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+tTfiBOqTviSupQg17XXFl7hkJWx6d3y7XPCUYR8zZEUMlW3Y87UaYBPJd+fj9qIj+H2s9EwHBRhyzCBzH7F2nEwjdjk31kcITJ1WkbbkjPFQ0evkTgRc4iAK5zkc2Xbw6coDb0bJ3y15+Nm6SB2BBoqf9cZ1RviJLI4ZpHaA6V9sFjzLTx3SHRs\\\\\\\\\\\\\\\/FMweffG+Q4HtWLON0lRJLORIbwhzFZNOtmu8zfJ3LBMHsgLVR4gkA+zmn8u0w33PeNhgNHENlMueUUHWhXKVQNOjBLwyW5w5u05CXeSdxIsQ7aTh5FaeFsRykKamZoZkhHVd83e7KPDO\\\\\\\\\\\\\\\/sZ5ZMwKWJh7VYzeEnqIGwgqJLfr2IeYyBV8k5mS+WJSGZhKhrmOtwVd2t+QDt60FtDuyNg\\\\\\\\\\\\\\\/Icpi6rbCkLZiz64pG1bcndwQAwGM6aEQTo9FOtYtXL6bm7eK2nzBxAPSOgBWx1Z6UhLIg9cru1o36lxa56wKfacDd4CrCd8sxNPYvxmtjibaigRl+\\\\\\\\\\\\\\\/DiCI3l9kZMNqHCzHuBtxoF0AaMrlv\\\\\\\\\\\\\\\/8Kur6G5shOOxYMeVxOPBbmDdCAFONGt\\\\\\\\\\\\\\\/SgG3HjSpiDFX4sw\\\\\\\\\\\\\\\/JIGRNZ2KBoWxszJZJBr0iFqvRoZ4szs0K4eNVzsI7GhWX6RG1e3KSStKkIHBweb7OPYlHKKyxE884uPpOsRdExwUBQb5ZhiEfy4Qe1G+YuZ0Ha11eLeq8cG3NkdnDL80hn4O1kozwY2l0VMud6STCoNggOyr1d0jMlIx3QE4Xwh4hNLw\\\\\\\\\\\\\\\/CVEDzfxRKEDmhrsksncXbNvYzoAAcniaGnLiCiUuaIB8k2cabnzEpXHq4qfXPAnU5AcWzk2ndqIfZ3RltuIBuSs5IThKhiOV5PN3dNTQ8GHVfARxYw3\\\\\\\\\\\\\\\/oIH0XX3VS6FlD8pbrdWpkFGHe6VRD3jiTixJlewA5pUjIa\\\\\\\\\\\\\\\/1GxrP50nK5CoLMuOahrccOM5qNF1Xz0fqecYEEd8TwfXL6W53plwt+OTVv7rqkdlx7Hi+NZlKKXOdaB+2ovfUNMRkSRImaGdPtHonHCtmPYsp2NQyVRMvwAnRDaUlhhZKa2\\\\\\\\\\\\\\\/Etti1GUBGBmfnJlnI2yNqUjKmtbE+zD1Zzcrobl40cKR1ZfBk4EED21uHbvaDU+BGLAdWV9LI\\\\\\\\\\\\\\\/yhpjIIxF2GZ8tyBHv2ubqzaJWQHxmYEhjKHY8p3awyyY\\\\\\\\\\\\\\\/e41HPG4A3qZoxZsEIxL1r6v8wXiga24j9cm23Oq3btMVI9aGTVb6hR9erTqnOamWTjifkStc7uk5XiqQGZ6TpL9522LwrLanuHEIJNSBFj0TLfX4EUei+OMwgirzfMTrt9eLToHGi6qBdRXEWcXfsmPT9Bq+uDgNwDYzm\\\\\\\\\\\\\\\/kIc\\\\\\\\\\\\\\\/hdNL+V5Aq66\\\\\\\\\\\\\\\/jL3sTpezENP2MiFqFH5ThTCJckOGv8NKMcGghZhZozrdDct97wcjYHdDCcz9vhSQFlMUmndYIolAus9qy\\\\\\\\\\\\\\\/d24t2mX5JYAE0ryYt2R+tSCBMSr5J51323bMZKPbc8NAuCiDzMrDsfjxp\\\\\\\\\\\\\\\/FDErOdUhaCDWN9oez5Rxzd4VeqpVOXhrx5pmlPXOUGB43Le+gYuy9yyTyw\\\\\\\\\\\\\\\/KfNnnrc+Y6Iy3Xo9KZTVVeDNz6Ktsdfqq3WeLrq\\\\\\\\\\\\\\\/glQi\\\\\\\\\\\\\\\/CnTf8cQnGco+6YfKnMvqtxVL3gZA0JT3qQC+HozUv370Ad37qDBE8G8qTSlVCqUdMPCy2cjXq7xPdsUOl+LUazlusqI04jTu37ZvL83XgMNyjjoQ+uA4MaG96xlwzr5ckkX2fY7BleOP1du2\\\\\\\\\\\\\\\/wlNTXHDzQRfcnost8Guq5Qpr+bU\\\\\\\\\\\\\\\/i8Q7b8UB0Dt+S+HqpJBGz0\\\\\\\\\\\\\\\/UEBqiHmipvd5Z67ZNMAkxt8Y9wMtBp9cXPf81dzYVeTgn+zzLkXxQg9yYbHJp8\\\\\\\\\\\\\\\/DEZLfJ+9tRE32EH9\\\\\\\\\\\\\\\/zo6Wd86Y3MKN2ojfBKSTeRqUWmTxsfMiNOB\\\\\\\\\\\\\\\/eim6mGxIXYjbLH2zDw3OQ8LcWXR77ko2vywHKKy584ShfaxIppEn2HOTDn\\\\\\\\\\\\\\\/sjl7QRC9urLf6eg+7F7hOFR3QAxWpanb7G65GBW5UbokHfAcnCkY0pDSUnGpqt72ULHR9VwcNARWqbL8DRfZfWKlTUKXx2X6l7nSluUnatE1nLY4JCHRp9vLQ\\\\\\\\\\\\\\\/W76H2sPerB02pGjVT\\\\\\\\\\\\\\\/ysdmcmD2EDzs89kQyc1yg\\\\\\\\\\\\\\\/YdSdbBM+VU5LEPxWqjngJW9+SwWd4T32XT\\\\\\\\\\\\\\\/5vulZqG9d\\\\\\\\\\\\\\\/ud\\\\\\\\\\\\\\\/5HyK4yg6gECh34jG6+R8E3OVQMmdvVMID31G7YnTvwlB1QenebwRqrMfjx22bVBZ8LyF+wI\\\\\\\\\\\\\\\/HmSsYn7j238DV8NxdBZybSqa7VcI+milRdMTNSBH1ZQw2asWVtV9+XBXXqDpDTgfj3o4zz29H1IR+vcBs0MRQGlzZem73EcRdNxEVoRGjelgMhOGvVJKcIq9nBSnjLmz7DbrZ7Fo2wDz2N7BL9MuQ8gTTZXLiKwsjyqOV1k\\\\\\\\\\\\\\\/mw7YWYHiRPIlw07Xe8roz3QV+z3zh9DlEY+HJFdO8QnNbvm27oydWENVr9vMf+KrKwY9jDdZzBp0UZAYh0uUiuYWfFOGqkHfv8qQYVdCgJQ9626c2cnpOoMHQwtT63t5ODFPkaCKijycvliO09n3\\\\\\\\\\\\\\\/4oOvt3B3sx0kCBbWGcvKG9AswFk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022+H2u3Wydy2U6epda2LbrGQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022ea5a0ca64cd05125d18637492740b0765166b832d4680b06c98035868a11e859\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A427.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A427.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0713\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0713\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0713\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}