{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022MW9Mo69AicgJXvRXy1TCu\\\\\\\\\\\\\\\/hfgaRjBQAPkA0SZMZmV0cXrro53xL5y50sGhCJiFrzXOS8x\\\\\\\\\\\\\\\/G51wcUNj\\\\\\\\\\\\\\\/sq\\\\\\\\\\\\\\\/85dN9wYmHs8KPeqa\\\\\\\\\\\\\\\/YCfusI1FmmFFZssWsBSHb0UmmqbxxoN54I1zRmQkndtPQqo3sILCNAfoa4gDhaS1STevRKiuyxlo0mlrDraHQ+5ScFo\\\\\\\\\\\\\\\/1QozHlqzsn3y\\\\\\\\\\\\\\\/AkjklAl6ib68aMtQkt9axQBM51IZtfy1Gjd3UYxjIm6Ti\\\\\\\\\\\\\\\/u20juEnShuP0jp26em+SYBwbv44sFgdxoRfIYdicXVMlwtYwUHyM5nsIzrPjpTmWww8auLXBdSKrZAR1kNE+dquPJ+HwyIWFCRwav194aXqi+FG61vNGIXNZOjhruDq5cwuuCY2xAZ5BpylhzB3\\\\\\\\\\\\\\\/ps2uWtFes1pIerVW+yrRagzXmirkXg464wpC95un5lwwnYCR8N5QJM2PhtbTpZHQdiFGclLzdJ4RQ\\\\\\\\\\\\\\\/5GxeHoin30hvyTs2ktps9q1xJpILfHZ5iL0HdK\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/1mPHAEC2oeHr3FwOmKqRpp5MnoJcqJRDPTK8ObnG1IB3QoK2nWjsw3EipF20jgl2P\\\\\\\\\\\\\\\/Lqv4lbpBOn9joJ2dr14UvpilmhTyF8D6AbDAHBUqBNe0rY\\\\\\\\\\\\\\\/i7xNA4eRpckYZFY4fKQi1cIKuNV9KrO6WlCUrAatpGF9zm9oyPZ\\\\\\\\\\\\\\\/QHXWU+xgbDHFvKICnAoA0s9IB4yfIecjFTbhweP7ob4WZsrpCtbEE43LdX2tmpLFHQ69YTpRu6fP6ddI22treUbXHhO1dkTKFmlcqCJmav00Wlf3GAf70uovPAE1aKwZfYFAwZBetCUmmI1THRt77PhUqlcQsY5vJrDI5pErGS7JuwfV\\\\\\\\\\\\\\\/GenvdFtP6ryiKqQ7+Bi+yCtu9UJUsLxusM0+IorK2Jb1230hmRYhQxXEUzADV2AhgGelYyvqnCe\\\\\\\\\\\\\\\/mGUDkvb0wQHIr4+qN\\\\\\\\\\\\\\\/QMemX+Cyl6u1ShajSQDuEowfb0MoKQV\\\\\\\\\\\\\\\/KZFQDFT7BHdnd8HaosOUhGeiaTCw78UmLQdFjbR1Ci+mK+OYGt0FWVqbIqQbN8z5mQdwekXvyx4byGrdGjNxKx6tQyZL475wb4uWFiwEJkUQPugNy4SJpbCPFq5v4tzUzePBH6ksJAP\\\\\\\\\\\\\\\/jveH0\\\\\\\\\\\\\\\/4LOeiPJbUC8kzw60hW9oE6E5na00bLJ+FmjM2dfVnIYsvHF2E45DNdIyDARnPzN7HU9iTaa4QB\\\\\\\\\\\\\\\/TnqnSTSqXyqOpSAczYi9377fKIfUqxKSwerVWlk1CVmMKoz1fOjXFHEGLhmOCDofn3QQ9Ag1BlmUtSnNR366OMDV+omKwvSed3PGz\\\\\\\\\\\\\\\/NYTdxUS7J0fT5EccD+0i00Pu03IYGcKm8NRW8\\\\\\\\\\\\\\\/UynIAZHvdz4NyedIUwDPFDa1pcj52hbcFy56xRuKB46Ioz\\\\\\\\\\\\\\\/wLi4tA+kZqKmRlOzsls+sjgp1t20+2m4wpyNCnvCZ7QsHltIx5G2J6hvf+OzNZ\\\\\\\\\\\\\\\/dxIFu3QK0xE5o3dRxrceFbwf6vf32DJdl1VrEm4bLpHFFPGg1w1oQX5KnrYqqmbK6Z0o9AR8gMeor3Lt3CpjQ0BSvZ0Xa+5cPd+vZblmC6sqJX2LuQ2jS97v6HgAs6s\\\\\\\\\\\\\\\/Oe\\\\\\\\\\\\\\\/W4ZAqniO6mcKZYoZcuRzjxbPXHYnHk7b2kC6cEDIO5XUV7Y1yjlnWf1AvEZURutLwsEPnZO4n9EVJ4xOuOS5Ds19FW5xxrTEbnlPIslUyXDPqnviNBu+KAiqs4NUCMgwuUUdRW+hQHno5gYPv+HVqOWvF8EPXpguAy\\\\\\\\\\\\\\\/Nizuw1YH1W5sTkqNaBOL1OoFas9UOY2Q\\\\\\\\\\\\\\\/AM3xWCMxvXjTyCPOM5hYRWjQVqceekv\\\\\\\\\\\\\\\/1ugJrP+YScw0M8o\\\\\\\\\\\\\\\/+D6i9lOKR6ci5dCDieZr3BEDeDKUY7Qt6sngyYWczakeXUID+AEmWKK\\\\\\\\\\\\\\\/k0grikLyIgA0t\\\\\\\\\\\\\\\/xkxVBxqQasSoH6catzixbh9RcwW5exCQ6ZfqqZoGt2bPoZ+9NPMzRcGIbhq1IHGAggJCp2iAG3kwh7X+EbVaNJ41xE0NSHDHUQ1Kr4ZStVFkYgFDtD5b8NL4fkfc8NIoClXehIVkKbIeCTOzWHO\\\\\\\\\\\\\\\/aAlKA1zsE4K2TM95fSFIvew7lX\\\\\\\\\\\\\\\/c918mepT8I8aC49B0vh7\\\\\\\\\\\\\\\/MaP++ORYbtS4hdyshmfqbtvHpGKhHpM10vLnMvQFw7mC8yYfvXKw2B5AWIgN8UxHh8QPBZ9jN9E3a0pBwW7P237FvI5CkWZPZw8WR1z5OrenkgaBARDQmizNZ49oBzp1LasN+2pmuSReXy8cU991Nvx3jv4WeBzsqL9JbEfPH76EqNfF9rua2W\\\\\\\\\\\\\\\/sbT0XGWBQH7JMkFBCXRkrMekhZWazT8h6MRMG1qZo9SOmTfTkCfsjgLso2vGgpc5A3L54qBOdOvc+4yigTMM60htdNWSdfxQws6dp1EheIvnm8qRMP3F8CHZidaYtX677O9BcZPZJ5NT8bqngMBqiYEwk9gGAyu4GR8QJpqmF\\\\\\\\\\\\\\\/cTnBQBl0hbJq276b0W5FxUlS8Gs7NdB5tMofzUsp2ZDGH24CS0dj\\\\\\\\\\\\\\\/iDVCO7WDv1+KBXAanJnRkZsQe8QVDSPGoyH4YEgCxkgCgHQaCdVtbyA1y5CvvHFWLxPEjUFJN+jgrfzWEwYfpjBKHlHmDCGXvY7yA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022EjITCNWr8G79B120MnoijQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223ef1e1cf3f67365fb0784d5c1073e3b7ff1fa90311d759516633e7b6688fee62\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A237.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A237.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0391\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0391\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0391\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}