{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00226aZUAvN3FIPATNBKwB10fwJYURN+OsKSg1RKptkRxEwuJqxsP7nV8KoPVBw6EMANLwV61aLN5oC6fw7faOzecZK0Ks5LOFoNVy\\\\\\\\\\\\\\\/FdzgSuPR1wRwWUPkQPuKhNEl1ulAd60iMGDtotzBmMUMFTYLCb8yAQUHhbHIFAycf99WXOU4st3lvW207DygSO7mAgSQMJEdQyW6tcjSe1WnY5nRrildYiF4HXjFn56fOvWKWG6zCO4v18vVe+uhvJPbKV7ANt+Jz1F8AQlBw49OnqkJKkAwa1whl4avmP23SJR56cwBt0zyVJC2mFN4w0hjGDZ6sRob0KYv5s\\\\\\\\\\\\\\\/3zFagqgIflZ1T0mACE73gk20eQCGp5HnyYncjflVCKsSrj+C8MJULvL8ssOOrnQBmkNE1a4e9bsnHP1msk2BSRgSe2oiOHwo1CoHVy+AJ6C6CEnpqqgLpPuDjQQUrOCf9peNrm+cYIEFkTlraBuxjZB4DAE4kyn\\\\\\\\\\\\\\\/VVa5ioVJ3TZB6RS\\\\\\\\\\\\\\\/T\\\\\\\\\\\\\\\/gddtwVUqDlEZrDy+ZttMk5a7ZxEgJxjsDEYYedkw08MepTL088cItsEhecWBuFsBD\\\\\\\\\\\\\\\/FmCqPydJCTyhFmaZyUUXgwIuITXRcUnjBouamG0EyvpW81sn0HV5VrQmRcCWe20p72qDdf1SO\\\\\\\\\\\\\\\/BQRiCogbnwN+Y1zbVFKF6RSo4zyBkmnVW+bwU1SwPu4a39qIcMf3l4VJDG+vU251TDk3ivQAADgrW2ak8V3rW07hNlEbSO9Gxdl\\\\\\\\\\\\\\\/rGHgqJm7bQ2c+RbLMimd1ZxVCePfLtiIrVnmVafZvButTrJa19MqzY7U2XmsHL3wpuI5YNTwTLtsod7H1xIY611zF3Xbc4VlzIb0ntN0T6bVD83dF9\\\\\\\\\\\\\\\/Y4SojjGzD2JG6NAjeO5y14ygHFwiKzOrHv9S7NOJic\\\\\\\\\\\\\\\/hzvIMoC2TWfMRwIAtKzD7I82PTJjTkxL00fhnOUGGjbzPE8kX5BFicq\\\\\\\\\\\\\\\/IhnoEAUv7uecc2YpojFZtEm7ScKNzAFwfpyTAc15kIcqA9YI17M+tRkAwJDe\\\\\\\\\\\\\\\/Pxx9FB6zTu0zLYoh7Nf26z\\\\\\\\\\\\\\\/FhJCMUQ9k3r6SEoPhE+bdIuRIFIO0IAMkg2bJ7I2IBko9fpgLHLLSjQMakR6OcBLVYpE3qbWnOOzUdzE0rKGZ\\\\\\\\\\\\\\\/UM3wTCffL+BNSKozzenaAATyHhEb\\\\\\\\\\\\\\\/ViMydOJaU3fH3SleEMiy7R+JHgiby4A7D9UvdfUkcdQZykoSYSl7qz\\\\\\\\\\\\\\\/mBmdB\\\\\\\\\\\\\\\/vgzE5JlalC2R\\\\\\\\\\\\\\\/S1BMyVN9hq\\\\\\\\\\\\\\\/eRZBOtrbWtIAxclsjjM1VkSWtjiiqXQ\\\\\\\\\\\\\\\/tMu2Ji5TkVmPDTrSogkCOHjpn\\\\\\\\\\\\\\\/WSCrwLkuNnBLSjUEoWu+lR634MrcJryQe2ALBrFnx\\\\\\\\\\\\\\\/eb+vAnXAaDF\\\\\\\\\\\\\\\/Kpjy4Nj5Vpy91HHtGlubmVSUbLAd9toK7FvB4YZouBCEdSl1Ejv0xEU+p7ZUQi93x5OqjgT6lSyqfC+kvrGs4vDd\\\\\\\\\\\\\\\/drXaxfKc0eTRMhy9l23DB3Gj3GwndWh6qbfcssNOtdRpXzWE3QoIUxuAbcqVIuznrEqrIj1TGSVWVywGU5p2OGP+IEH3\\\\\\\\\\\\\\\/Kx9By3zIoDQNQM0anb2oPB63G26VCN5y9i+zDJqodV8LaogwU2iOrtEyzHXGGHUyrBovs+7uBmPheaRvf9o5JU5EEAZd1E11b6ajTNd4h1OYqkGlNt1l3DSE80O84xcec1IHwwY57pX8msDzliwWNw5cluc7Sfn4yjPHP4kIcjed4LwU4iqofNjkwobPZEaMniFf8jLowpg\\\\\\\\\\\\\\\/RZWvO9HTP58wAMl9ECjW44M+95XshFidu9RMHk\\\\\\\\\\\\\\\/2Rv\\\\\\\\\\\\\\\/iWIPKkv\\\\\\\\\\\\\\\/9SeAOX4UKE1pe5dWCzCtgWW36bkqlII5zG6oFBj4Wu04VrCaH2u+OGVQdfPIPawGhuYOywees1PlAj+MMziSnRwnBzVblyhctcdK4WAcFQHysrgDrgdqKKQJHOcADc\\\\\\\\\\\\\\\/sz6yUi7HpN2LiPkBRNTv4N62I2nHr+gwZ8HyAs6xMSw+Tuzgh8tjvjF+ytY25SKVhJO1G8niLXunI562XBxoXdjOQ4gxlKpcZNk08Kjs1WaG1ywmZ7fiEpBBNhZIUOx77+8xnd7sJYlddiWzVoePPlb0XqKWt+sBvk7MG1Tr1omXYQTvGS\\\\\\\\\\\\\\\/rvDQstuP3cujTLfTfZ5Hs\\\\\\\\\\\\\\\/haWUDa0ImKRUF+nxZEsEMA4faDzpfx5HqvwyDG7HkMizej5GMu2Ju2vSK\\\\\\\\\\\\\\\/+o3jo5srbkNKQIWIQp4myIHLRIsmErYF4mBQmirpsB2JZvdmZxtH5ofK9L89S\\\\\\\\\\\\\\\/4P97lt4pNMXdKvkD9mJv2E+0wy4eU\\\\\\\\\\\\\\\/n37ynj7l2P7Iw9D\\\\\\\\\\\\\\\/I\\\\\\\\\\\\\\\/mkyuTaD+shx4cl+E6sMG2nz8cBty6g+xxuTo2BtJxq\\\\\\\\\\\\\\\/68lZ+zTVjNaVAgd6TkTaKA3hggVndt1fOxpvrIWTw6UJdNGlIAsbBE5nHlI4Vlwl1qLBoyP0EngjG9YB0H+fpbF+Rs6ub07XblE9fJL43pU2OO\\\\\\\\\\\\\\\/ckMQv2jvvlw5PHQwZwERKnTvafkUHHoMMc4a0gPyPw+FRfg3U8UN7RvNULcAeCuGAygnibs71l0qbwN06cgDfIdWl1aMIT1iuMddTyqdzrfhAdIO5334xZfXeLWjLYyNVGB76IsMDwMTIXeOhWPrG52bWpMUrs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00222MBDmBbhnXkLbz4Stb9+JQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c57353c6ce48ed2c1ed00f71fca23736bd105cc156982ed9b6b81e6196bdcd79\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A177.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A177.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0289\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0289\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0289\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}