{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022HTeFfiubz3lARFo2B4nwaq\\\\\\\\\\\\\\\/jn4Xv+iQteIhginITPwcudVZDKgv4x7LjxCY60dPzIwNMo20VcbsYDPYookY9PFtF7DErShLgZGLuJp8vjW8WnxxrOlpj5Ngeqa91wJjvazoZSAmLYOpw3nMs6wCmG0zQGDR3lv55aGz+EEtwRMFaKcriZnjpPGNBFqXy5OxQuSSQAGF7UczoH+F8RmvfZsLNMCnR408\\\\\\\\\\\\\\\/YEo0BpewWruMW+wTJer4uz+dn5BejFncV7NMmm5Yv5RbWdaykOuT2USs74XEtXwrIDokZHb\\\\\\\\\\\\\\\/39HfZyN4LzZTC7tw\\\\\\\\\\\\\\\/9awoBm8kpUnkPUbpS4hKRjKPzy\\\\\\\\\\\\\\\/2mHrzwuK2LSRY3iIu0bfa9Dxroo6xAON8lCLjAVqATH54NofJymfcAsC6plJZY\\\\\\\\\\\\\\\/hCRX7Fn6ifLot9EhvjWZt7dp+WYVAYMjZ11BZ72p1P4Vyrzb\\\\\\\\\\\\\\\/ubPVKnioRcs9hW6+9a30jFs+cYpT70dTkcO0KVGhpFRHtm2t9Opesf3j+E\\\\\\\\\\\\\\\/N3aNbdOyL+qO9PS3Tu5Yvyj+ZhR2B9aUwkGUnn02KjPXlbGD1iNIhMIBBKUxsIAyGz2grepMmS1vL\\\\\\\\\\\\\\\/v2bOqhlpOBgxeQ5MyA+50Yq4Gtw5EKGOkeYnH5Wi0BPCtYSzBE0TfhQquMhPcxAY8BfycZx7oWrEw0S66Q6d59ZQ5\\\\\\\\\\\\\\\/+pDZ1L4lqQr4iy\\\\\\\\\\\\\\\/Fgs7bX4CqQdG4cegb8W32puk8\\\\\\\\\\\\\\\/uW7vuGiAyFp1Gnyg8Zvox\\\\\\\\\\\\\\\/X4gTmICNzBJYFIyFEsd79LY44nqkY5hIS1SU6PQMGzCPh6QKyeybtDK5FOogNBdO2mbXh64aTT+SXEsdU8SXxdTk8BuiGcrcgX9LoHTBWt83+la7rWtNYOJwXY3RX6U3oP9TWC4Njp5Kzq+j9PiCopmMM54rNyyRIJl9eS2ru8tvbGY2bx+5g1E0r3OLKYzDJABOd\\\\\\\\\\\\\\\/r9WafQ1+hzY1Rt3OWNfSE760gXmodX3edZuC42lV9JsYR6sRIaZ1j4w8kIrrBXxvSxs6\\\\\\\\\\\\\\\/LCq8s79gmHvn9K98HkbktOqeVQdpc4Qrh7Cg+t7F7gfhsoTkvPIEzAKUGWs8qRGKwiOG7SJ+Na73W9kE+8odavC8TXLwO40H57OZ9aU3H4WrFhMwN1Ta4HaEuzgW9lpFiik0iCDMBpGFPl7g3XBLHBRLV\\\\\\\\\\\\\\\/N23t+A05RnAAbc4dR7pLGlW0UtkoTfLfmpNA+PVvJap2O90Sxb9IKQZyI9mMCFJVp5EHquSoCbOEQNTX3VU1hwS+J7k1jJCvGOnVfJ2r1jGzVv3tjsw\\\\\\\\\\\\\\\/wfuY24JpmJyeGuvnvr+jrFpAk1PPfmSh+fcPWYYuzet2ZNt9ap2bizixtkwqjrToh8EObktNYwkk2SxpUPTgR9cImHRtGSsnZbDDTyCZKgcEdWtyOQCsEH7NIbtsHwjxkSkb83dVovkwfpzoph7EUasQ2UZ9GClKXuefBGBD8lOBp+4XnxEx9z9pgWjOx7OAlDqOQznY3kjXy4tGVbqEpqFzq03fh\\\\\\\\\\\\\\\/u+oFDeCcKXzlWbBsn7w59f+W4diY9UUZx4i+mP2BLyvwPazcW\\\\\\\\\\\\\\\/FvxIeoT\\\\\\\\\\\\\\\/RegptAO7zQg3jZ8A6Z8Rl4ux\\\\\\\\\\\\\\\/Q1kJcH8kbtTsAcgYMfhRI05T7QUZVydghDQiVw6Bbnme3GEykfrDLnuEyvRnaWO2HwaFIFY+BY6DcxYPUMzossy+5p1yAXo84yIqtRR9rIXYc\\\\\\\\\\\\\\\/NMXLJKSrg5apYWOe7ufeofjDJu6Z5H1OtblAlRI1uf2HeowewTV9oGKMHQ6Ka2fCQ8zrwrRbnBiLKzxWOtdQzSUmfzmfKD7K6OUP99gR7fFMvQ7iijqOToKnF4Q3N2urySWogpoRf3+NM3j6LE+X72nk19cwfE+xkYaW0Ko1av1KWsg0gPobiiy6DZOR+Qb7JEBPOyPpa3C9nC+3uKnk3bF8IX7oSOECw8rJIkIvrTKAWnb3lpfkJSUofDM3V+2YEQVzYSCANtKYq8hcRKLEMl2HEoTE1oPCEB3Hht78EOzXzP\\\\\\\\\\\\\\\/MKPed90t3L6lnVlNtR+hq0PX0Wz3Wc9AY3i9\\\\\\\\\\\\\\\/2hqTav+dbPCom5Z0ZQzHKhRAOiS1q6XGRjWYDz3DBiBqAKLq+g8ByaKI3r0C6aQ3OBKOXHSR0Uo2QvfyD80E9i\\\\\\\\\\\\\\\/ZiEQur3\\\\\\\\\\\\\\\/O\\\\\\\\\\\\\\\/aKilhTvuCbkeeXZJiKjxjQj5AIDb8fcKT5GsQczzHlKozDLpUFlfjG5ClCs9qvA20VWPr\\\\\\\\\\\\\\\/kEWr6Dso9PBU6jwCt8fkNZfj+DJFnNyZ+EBVDYtbUyhAhl\\\\\\\\\\\\\\\/8tc6PdiUWiauo55XNMOUu5cPOxU2SsuAmSZMFgrAV1lnRiOOKhn5rlcnxoKoeA5mxUo+iRbGakfQHkngY7f4arMSc0wqgiulNfFKLdXDG7yfeKUGd97oOiwN2nnvyqPdsLIFVG3hVBUbCviFD4xNikvrXeksSNHp4Z99ttLG3a2h5822XEJwo9y0HomjROcUd\\\\\\\\\\\\\\\/e\\\\\\\\\\\\\\\/ZVWm3NN8p0NpZHPLLHbkxqlX0UEyQ9KoH73mOn\\\\\\\\\\\\\\\/AwmZk4lj2HVWTpWdaV49baARTJolKhx\\\\\\\\\\\\\\\/hUu3duZzZvP3eQXRtMa\\\\\\\\\\\\\\\/KZqVg4jVutmr6T+0yhsoq1X+lHiuLh9iWpAX4UYXuQ0QpvOQtV3Lzd26Bn5h0SoDAs\\\\\\\\\\\\\\\/A=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022B6h2+WlhWEuo+jx1A\\\\\\\\\\\\\\\/AteQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002228eb319f5eb94eeaef6e04a1bad5b94b41aead02662adaf2d25ee9b09582dd4b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A309.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A309.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0502\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0502\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0502\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}