{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022xG7V47OIyqNS1M9qffTYNJboFvozDXjJHv43gT42yJ0nTuehIvvOKeWuIP2YV7UqOeGQEiUirmBoDijJOsJFpJL9oitTmTGePeKoVExRoL+23BoqVKAuSfNn94+j7aJ33KV2hQ7ss+30n1eAPUh\\\\\\\\\\\\\\\/BcGcIFwODiProZgQ6+Uglan7i\\\\\\\\\\\\\\\/GW835vVwqvKBE5iRP1mNt3NXUWmJFf3q+C+OPMKeYle8vrlxKlY5jPVlm4ohooazjFBG19nFOLJ6PDZm7U\\\\\\\\\\\\\\\/iAexOurH+1mNAsuL9HxWRZxksybgNP20Jhyle9fGxMaxHGX+3OAeugJ6LAEs\\\\\\\\\\\\\\\/188wAE0gSFY7LFQCpA5Pf50tl5lvnShI8ZPvsJbEqihhRSOf7L\\\\\\\\\\\\\\\/AS3T8K1S3+Vkz0dZ14B5hIF7v\\\\\\\\\\\\\\\/44eOq8ZYMA5vWPW9gHx87E38azJdVnIW2UmzmcwgwPxQ9m8piOQOTSsVxBoK\\\\\\\\\\\\\\\/700qLTG1GUNpMucDIwoy53k5s64ir8zANk+GbM19cvgDTqACJ4F5RazcKlKbYhPLlvYhSPBi\\\\\\\\\\\\\\\/TZDnbQiZQ2kJ5EJ6Y5znI3mwz0yUGBvez2yFFHMWtUqIDNVqQbPf85x4Q\\\\\\\\\\\\\\\/lZPhO\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ie5p3I5LBtLhVFtrobCPo8ZFgdYu3kh91iQ\\\\\\\\\\\\\\\/XDPX5wmglSij3na+t25Kncg8JVzq1kZjlD1u6nKyyAU0SH80M\\\\\\\\\\\\\\\/o3RI+KuJfrexe0QQu2Nsr\\\\\\\\\\\\\\\/fbgPlFl2UuL2ODN7BwtAVC2KaNrZpfOFO4BQd5NETQnpmkcRLiuEkRSlIR6rbF0YraHB4YphDzekLkDFclSq+m9vg4aAJ3DaKkVfWpGhLaU\\\\\\\\\\\\\\\/8SR6D4ThDf6xG1jhjYsEuB3n0AR9GJTWYYmrcqI1M6kF7mZ5T1HmajsORRXMm7yuXafSa8cy52LThZYxllvTXJNDnR64wap3sLSKLkUYOxMNHlQYI8fa23U6U82ywpL8k09zS2bdS4rr6nS24GnXKKuZiaO5c0hIpdrVoYe+JHcuswMTmBYxDjhlcj1oKTMPoMeSvi2ijB\\\\\\\\\\\\\\\/s8A+4v0uFivMYtYgBpiZBcZ6h+\\\\\\\\\\\\\\\/cXbistihtA6PLl9eBEwINk\\\\\\\\\\\\\\\/40mfN0bWiiPBaIeXYC0ehsuLuQVqmttLrYv9w98cJPzPWLPHmaNsxg1VsVZmyyKdj7Zh93l5scpC2FuRd2jDjV1YDQq0mvauOthTJZFf4jB7lVTroYGoLH6+t3TkDgqbmKeCwmOaLWaIapGZC+73XE401\\\\\\\\\\\\\\\/LmjBwas39k3uCjZ6C8GzRpeine0PnBQR8qqDJg58qhGQpLANXxujjkseF\\\\\\\\\\\\\\\/gV\\\\\\\\\\\\\\\/3kq316i9xiSR2uzKDXSMtZREKFZZLjJ0OsHSU7ZUEltP+Bu3RnVsmDCc5QbId1jBQiotE2JcdSmtaoGFq3Yn72Ka+aCEx6S5rKxakbFEg7DVl8VV1PXs6J2Foqv8CZZX8yhVzieoJNUbEL0SZq39Uv6Enqi4g5\\\\\\\\\\\\\\\/jcCLJltLU4ZHBw0pzTeK0twvydR60+h4YVBOvBYMj8h+suB4KrqR8DjsQ8roGDQlpfgF95KR0II1SdN85DIrsu2LW+HIGPBhQxTDurT0RszkaqnRIXlJnVAghu\\\\\\\\\\\\\\\/7mqe1fsrRUf6OIgzJUH6kEh+zp93rPO3\\\\\\\\\\\\\\\/hgNmf3CyFBGDrKw+5WsGxUURAE4kmyyhnSI92eqCO4ivHL03wCUIQPauFoPtZNJic+3JY0RMgc0Sp45WMkAl5hWzpqwFDIbpi8k3+UDN9yOQn1wqh53Lnf1cVYgbaa4TTgrOn7XKr6KnyoV5LAP3OctGz93KEyuqWZ2WzJVdO+RMHJMx6OWkyRDJN5FiC1hliWeXDxoSEWhh7mKopgPgqGT6Dqe5PblTLqqgxi61CIq0piU1FwiEWHLA8P92FQ0C41alh27ASNGKXKfxI6QMhSHciScYyt9gvQDTjXkGNJdO6YMl0v9Cmmx6Gcm0pQiIOHjS6nfjIkdOGPbjdzGnaQsEn8oDwqWYVodxB9WID587zUnTm2PFnMB+9dnXu1vmYrfHwP6pJOcs0d\\\\\\\\\\\\\\\/BQPb\\\\\\\\\\\\\\\/S9F8qH+nSZB3Q4\\\\\\\\\\\\\\\/4vMyYwMEsn2miDRA8JMDiYhEUqjPe0eLOMWxcS37l5LAXPx\\\\\\\\\\\\\\\/M\\\\\\\\\\\\\\\/6a+eibJCsm5t2E4lFgobDa9Qlw6IGCEzBAIbhLAvg\\\\\\\\\\\\\\\/FX0vqHiGlt3zAGfUOsHTBmg8Y4yxnYRh1VjRXemnbqa0BI8kcFYh8bwdhOi4GjYTSGNa5JD8RT9imSkDxv+i3xhnFJlljP1yZRHchfgjNkzqx80bE6CZ3xIoCfa62sV5s6s8fR2d2cJ30IP\\\\\\\\\\\\\\\/ZdJ2u01t1JCzUmXJo12R3q53UZv+KQW2\\\\\\\\\\\\\\\/E+z7UhT5FZnKZlD9t0OTD3l4DnShsmlOv2TRn8rGnruQclTIUpWYl\\\\\\\\\\\\\\\/31LgcHhir9oYcG1TCONuIdVEnABcOHF5rOL6hFIZzySVvLYgoOGmXIleLLDPlIhh0k1NpSHT+A6HOOb4lbpIBiioKAl7BhLt04fd\\\\\\\\\\\\\\\/Ze843viu7gz5kSMd4qEdnONXwDzD89+MF60ZTqJ+zreX1fje259Q\\\\\\\\\\\\\\\/yn1gGuGKRHCvdoKwGa8VxaRWiiH7RyPiW65t5y5yjhqlC7eq6JM+\\\\\\\\\\\\\\\/hS7YA8WxPDgfn0wYM5fdxblSLGNgQiWsrjZOiy1DZGHQqEPOACcI39NpOi4ZM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00227wt978F97Cv83CogzaYkBA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022ed67e7896a987b242d727b943e3d5b64a54036e5965367cac2bad5efffb82249\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A343.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A343.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0571\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0571\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0571\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}