{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022EuutdxCQ1XEIr+QcYINbcc7lpnG0J5Sr+dBiF6R4+jn7lgiVzp9NWjJdOuwTZ7d8Zvtm9p0BnXEELlz+e9GCdlr0dCj5xaBoYRanyYjxqIykLqOcPYUbAlQbNkrjzqnaGHqYFAd8TxfRRcOKNF6FoAu2nrUq2WZYWBu9LCowqx1o\\\\\\\\\\\\\\\/QLCTXASkOX7wfKzeymCyFhwzBeJaxhSOxlwiYxZpC0ccvk3TmO7JcvXHhLwtoy2JAFpRovr4UaS1S\\\\\\\\\\\\\\\/+1YiYkvA4ze2rDoLs35gIFyiB\\\\\\\\\\\\\\\/GulYlU9b4a5caUFAfiG3NW6i3IibHALkMVQoANxUiRXFOy8YJITZsJcFLk16P\\\\\\\\\\\\\\\/aQtzDvTP5vnef4K5E\\\\\\\\\\\\\\\/1KitEDYczB\\\\\\\\\\\\\\\/fsbg1tFmnIge9wRCTuvu4XbeEZjavR21REcP5kyiMkt+GcpBsF60sqyZ8Sbej5RlJLpFDqJdodUILPrKZRfqtggLW3LpeEi7IRpVw1VBfEkkM6MAksYjWkukLvOD1rFPala8G197Xgkp\\\\\\\\\\\\\\\/y+pHonZsHVpwHRbvqIwLr2\\\\\\\\\\\\\\\/UTVbxL2j1EkvxfuwKGfqRMrvKLDnethfZbkOeHtHpnzpAGOHKmf3i71OObB660N4fO\\\\\\\\\\\\\\\/1kHzPPQqXIf45yjWr7iCmL6GkXHv1qLL4gaIXFf\\\\\\\\\\\\\\\/0fRxe8fWt\\\\\\\\\\\\\\\/ADkUkSHSW1F\\\\\\\\\\\\\\\/qw+19BAW5lkgwwVk0SOHUEFj2jFTrd7O9\\\\\\\\\\\\\\\/fF237KXDquCuGYkOz7LffnTRhhDwU4aYob410UiFCowEwL4OrUkDHianscsHJCILeire6e32v7XdEXf0TG2VDI7Z6nZCCekRWMKt3TqCm6mCAECCA9dyBes7NP5zk+KjDtYG5BeyIOXQBqYAp6O3XULtPdmVmJdr83ZZ1Dp5gjYoSI9rDxYagr7eZdtLlABxbjdroZXkzXOS3uzz20qLc91u+giKELjlY4GD+Ch+V8lIVvX1pF77jrMb1RbsEqsf5+tln9VRNPSnuLLnSitvg1Tun05OAHIAAaI9WEeJ0rS2Wf7tzUn6hTl4YcKZ\\\\\\\\\\\\\\\/OKDTSjfSL9sgrbcjdaLCcIOOz0qq\\\\\\\\\\\\\\\/0cIM+i\\\\\\\\\\\\\\\/YSsTu1m0DbaiqpUaG4edPERuGRLdu98\\\\\\\\\\\\\\\/pXsCvBk+50EOlBK5Lv\\\\\\\\\\\\\\\/MBZFEqPpNHxgW\\\\\\\\\\\\\\\/eUwZ4P0fHva8RvodKkuNN0NP1StWWNFVFb90\\\\\\\\\\\\\\\/rAlooKP2m6pab6orrNH86fz6Y1yp1B6mVZr1aNmT3kcPZIlfVkq3EYM29PPHAk7KWXREU4pnzfnZWKvmwUhWX2eQ1mVi6rigoAsmJa4s4\\\\\\\\\\\\\\\/8dYLskactPa7lBJEqGTkNtVqtgP99tjCjlyZflojeAegJiuJvGzQdL9y0p1wmZXj72lFzO3e1NjGPmC9PWzf8\\\\\\\\\\\\\\\/qnAIqYjFQr+K72vohYBuxN4rb0qycJPvbHVDsc\\\\\\\\\\\\\\\/WiXl+jbBTqpxdytDDz28A+bFANLyIoxwUJUHZOpWHrC0sGAuHMp2tAeVgWlcLpTGXc8C6t3G1OvrsDbkPB01IWh91Ay1wYlcJ\\\\\\\\\\\\\\\/FHskf7KsoxNF3k3xLJNfJXj0FMAVMHLjPS0CVHbG+1DZQjK1DGDa9H9DYb+45a3uvN6gnheybesxs3w9ovw2gu8VSf\\\\\\\\\\\\\\\/h2JbYNq1kM5tJhuoJqWIP0cKvKyliGtfkFo5vR7FP1fIjFkxEza7bCqL+K7\\\\\\\\\\\\\\\/mOf5Ahl+lKWj9FwX6mTiVjiWvSgv05D4xNd+9kW13hlpCPNsoHGMYD6J5vblX0sgKkoBcqOkzE2FyXH\\\\\\\\\\\\\\\/gp4Mngk2EkI4WPhsgQo\\\\\\\\\\\\\\\/WDvAzONq5upt47DzyhlptrhdIYCdUiLTSn\\\\\\\\\\\\\\\/F\\\\\\\\\\\\\\\/iPKJcGD5EZWIb3MgqcNjMBBhaa0mMylbfCD8SpKWosmWcoUM40LRs6pElHZC56C1005AC5g4l5thgkw\\\\\\\\\\\\\\\/NxE3JIXcOElXFLMdbaCYpvEGcx4NrgdM3BgbNFAQ8bNLjR\\\\\\\\\\\\\\\/ejuAw9CvR3+tKXnLLFLmalmo\\\\\\\\\\\\\\\/i0uWxomqWy9BfU6U+Utq3aK0GZnS69YZ+QsjUsWdeJzmXvEqBbHb7tvglPAisPYAQaTgD8z2UOf4MyJxHKPbU2iilYDYsmBtvaOpTfnuEqKCW1Li24EUWAsSQKKg5ANd10zHleO0DCguMNknGmtDJWO\\\\\\\\\\\\\\\/8iz+C9X3Yg4pF8Uj\\\\\\\\\\\\\\\/G+NNEilPcTQM20oLNxRi38DupV5YhGZJdpdopNkUe8LQuJhvNeNg39cNtsbmZnwLQ08xDt0qvKg1LHAvUkEuInlFAvPu6kLhBD4Usw+BZiur+5ICX4G61jzmmA\\\\\\\\\\\\\\\/jyKWizGPjDqqWq3\\\\\\\\\\\\\\\/H7C8D57FUahb9szB\\\\\\\\\\\\\\\/6cWL3hkUNtIH+1Fgn0y8FtaropdWbvvQH1O6MjvT9wHRFSyoVTTr6pj1lMD4pPNaDRH70VNbAXFiC4uGz9scLslmFbah2kMeG2Bz04UkwqYzTKTNsCDmRcuNYtQZenVa8YF3VLeZ8X6jj9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/wn\\\\\\\\\\\\\\\/mLhVaNw6GMZyfdM1jpN9r9dD7rFT\\\\\\\\\\\\\\\/m154\\\\\\\\\\\\\\\/eMlANT3v3Ebktm0afdFS7EKFrGqpS4ZIREfxggjFQc7TjnJKB4XHq2BLj2RyWFzo72NfT62mXh+STzVu2l+kwF2T7BehXEmi0j\\\\\\\\\\\\\\\/xSwJxdIgbELh941zo8m6t7Lv8i9v4oO5MvdwLAmtv7PsvBsyc\\\\\\\\\\\\\\\/92h9pKyvL\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/URwCZusNKXnZdgEDPA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022yQsg3I2YhP11AXxY\\\\\\\\\\\\\\\/ggHcg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022bc0dad3a5a1b4fa757e53197b4688ad4d2c0850d7409aa049b2823142820bf85\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A425.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A425.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0709\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0709\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0709\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}