{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022t\\\\\\\\\\\\\\\/JoSqXoIN2P5\\\\\\\\\\\\\\\/aBDpXBFhbrIhp\\\\\\\\\\\\\\\/m4\\\\\\\\\\\\\\\/RFJ3ud08+sFGkxnyG2vavTDEAlC7DVOpumPdStsRsPRLZLiljrVom83ggsCCGa3z9fcCjNn9DdGEuPv62\\\\\\\\\\\\\\\/qjBONWYsrIEJxUanr321Z4qx5Gcy6m\\\\\\\\\\\\\\\/z8IA78Zb69BLJpattR5h0RtHIoxKArwaj73E\\\\\\\\\\\\\\\/UfKaE+k0RlmSm0yw8yq5QnUfkrL3wyzRLKZiAr+2bs0KnHadotEowD\\\\\\\\\\\\\\\/VR80tmEhwBRXid0kFANqpnOK5Q9XE8szzH\\\\\\\\\\\\\\\/PaSImfL6y+C9fz+ZGfKopa96Jkt6VFrxautBLIiMOjYFlVAbgqytqFXf6Oa5DN7I2hKF\\\\\\\\\\\\\\\/D4BQhJ5YILcHAmzDCYWguLqXiuW1IjCrxl5z+zVTdXxFkOIp8w3TsHFAScZzUxk7Tkk1JPx5GH4Qn\\\\\\\\\\\\\\\/1Yxw+\\\\\\\\\\\\\\\/hoOr4SfngsdXcWYrWLLa0S8p6ovJ9i5\\\\\\\\\\\\\\\/ltUJgNBtrRJwpqbC3U50JoGglnkYyRONmhu69viLZ3XWzKoK4zSSZHscELSjxDiQvWlwzH3Yn\\\\\\\\\\\\\\\/sYIf0H8vL\\\\\\\\\\\\\\\/a9IreH\\\\\\\\\\\\\\\/2OWlgZSumohjBdFAv8YB3vNaFX1utkW8Q2h\\\\\\\\\\\\\\\/1b9+FSILJt1idHfaJR4vQa8\\\\\\\\\\\\\\\/xwBXeyC53UXbC8nwHytOLWMLz2oFMVSdWPjWVOHlYW8\\\\\\\\\\\\\\\/t+5Hm4pFSN551rAUJK5wgsUIPQlDVcPOvwRXBpVRvEfSRY2EzPw10pgYix9ZtkNVsMN\\\\\\\\\\\\\\\/UKikq7jS5KBq6kgOnIP89VlbM8Z3OuyA6aI6Nfw5EgaMEEeQ1SVaSZNPnC+7mhO5SkNw0XuCciWhwbamCmvHEPcw9BfwB\\\\\\\\\\\\\\\/GRhoGZVrfy9NFvPAXlRCoXIRbkAjGGic2pxXpeQ\\\\\\\\\\\\\\\/1cUz7pyQBo3eYTOWymucYNgORxK3xDWj0yV4sDTNl4FJx1m5aJQC6EuWc5YO\\\\\\\\\\\\\\\/jUAXjunM1sTznh4FPNXqVH81\\\\\\\\\\\\\\\/dLdn4zsAG1o9HJPRPA83KBsQo10Rj6GfbWY4pH36wrvXzg+aOg4ceMH3Wit4H2OdHbxJXZKA\\\\\\\\\\\\\\\/VG9e9OmL+Fv4nu+AZHo7ms0X7GxDkJoZvLYBu2RNNepby56K5z7BXI9F8CU34noponHaS2ZknlcHjxbHFRtCHHrtzKvAsEoeZjsMdK3jEKHnsoBU9Klw9suwGxDKL2gE0SUulg0sbMYHHnv0f2cLUj22aeR3kGSQreFtssLRCMqkT74xuj6HLMcNU1CaceoaGchYQ+nQnN5\\\\\\\\\\\\\\\/SvtF\\\\\\\\\\\\\\\/NFoQ0lhiihQ5dL+KBxzPkQtrkdkmnVSSLsnsN+dx5O0gUTn63GJDjEoHCmtd9LDGpp4bOQNl331tTurPeTwTiqRvBOTash6WfCSYB\\\\\\\\\\\\\\\/3EV1NDNpfWG\\\\\\\\\\\\\\\/zs3yBaEuSFUkq4I7gJmDMOgKvYcc4o0+ZVk64WrFAEJ\\\\\\\\\\\\\\\/Fb8aQD8MQQ5f0fmxvyLfE1BWrQs3TgwmF9B38oBTEMdXLrWYW9h6+wTVaSCQCaB6bvJtTs5T+VUZBGpjp0JIr3StakKOdegqa7REWpRRI7klvA67ZCiYUvqfaPFBc\\\\\\\\\\\\\\\/oCFXJ7CQOivTyBwPPsZYm3BPB1Wl7wqTcwymg48j0LUqN3McFAdFiQ+GYwhAsJiu4Em7JJfhhdPZJCMglxroUq3354bz3f0hDEjyI7rd6mhPHeLek5Tf+TCxQFROscFnbJzAE9UlBK23EY7XYWfwel6wJ55PXNB5QsgvXvZxVjf7hT027HJe5zY6Vmdy85G2Luag54oL0pKT+lE2Anz3zfpFtSCG2\\\\\\\\\\\\\\\/LypohZBbSxx6e9vPXn2teFr7Gcca395i4zRJqyqdwQIsYY9VnkvUpKXrWDeG8sgjoFBb+QTKNAQJWPQB6pcE2+Vt25woZa9PBWsZrUoT+OpzmU54TjnhCepdniVeJdIsNfPLk8G3kGYWJNTHar8xDkkJC4zlhePCKHh1RbraQxzm1WbxgjhxFdYlKzYC2VSh2XLbfA4hQYZ3O+IX+3GrBHrijeyN7bBUmkvj8iFf0yPRHoQ0VEFT3bUSDbQoINbNbQa4cWFPob2WCw1FM34jAlxcbR4SRirlZHZ4iBbqDvuK1wdAwEhA6mXiwEn47wLWIo98FsChVWhIJSYa2Uv4GPBN2\\\\\\\\\\\\\\\/QYEjGpUhAH8JZoNteVrj677dOFOf6W1KXw7MrMJsOv+LJehS0RxsgbsvL8e\\\\\\\\\\\\\\\/qrCBuJl+o121fTGDcFpgIwflINd63BLqSH6sBytFssOEk1uMWqe\\\\\\\\\\\\\\\/6O06wirTAuOtTGF+B49peCuOMTMQSQWZGkOgdp6KvBp0SSH0ZZ2c08tKyYTaheDg+0+iejzeejZhZaExre63Ce0g+bLo60OqJ7LfUywugGOfEM1JanmdEDSm4JG3Kxwg89cnWQpBReSkGo7fxTsTKO7Cf666Lxr5rMgKKepN3bzAyLhET2lfPkjMqsesaFRKFLkAX3zguf3I\\\\\\\\\\\\\\\/n2E+081OKIHhnIBJeYVFXalh3mIeGwVnvlFUiQR7cWEQ84wOBpdwCFqsS8IiqXBos86u5c1h4OXmJ3Ot564oM3zPNgXOCwXcC\\\\\\\\\\\\\\\/LeKTeSMU2O\\\\\\\\\\\\\\\/oVQacw2Z0645xm4RBymWbSVQNR5R82irD7ZwyTXv6aqJOTeLIFkEhEsLrSVbZfJCIJi\\\\\\\\\\\\\\\/Q9i8Xo\\\\\\\\\\\\\\\/JsWU7f4j+89flhZGIn9uImzhWqC\\\\\\\\\\\\\\\/0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00224klvdxoRRK7UExzun6wrUg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226f876c201e0999d49f672601bf8c9338e0b18aecaef2ff821e353de63597d89f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A3.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A3.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0005\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0005\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0005\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}