{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+pss2HVODgE88uPp+TQEk861Qsro5029MbKT4oZIwGAAeC9Jbz09IDjQaA8UzKQqRQUag1aBMkrV8kuAUGAPW4KKbjrKiu1xS\\\\\\\\\\\\\\\/E2V1HdKzs\\\\\\\\\\\\\\\/uTNIUAM+vMgPIeA8DjGdUiCr3UVxVLrDPftRzqr0dcr57CPsfpaTQdTfYgiydMcCqWFshjN8IrM2J5cnwJmFWC46vMMKtH0jAUoYnIo3cwpbRYngq234y3A41den7IUORENEFyUYXS0ItDvCQwuD84ywkmk2roP3WG0K5LEe0yuKyL4s5en8NGdkkziW3jgzDMUqqxrkDnAQEugLJjKUoJR6VK57xydAFWBHRKDd+Bp+HZdFgw0sIyicajX3m4isdyaAS0m6i7Kbi1eI\\\\\\\\\\\\\\\/sMb348ci7Zm8dGp88pjdv5IA52sDAm2HnvejxL3vPhTLMkZSsgu9wh7levG3mAjqpDzlSd7sI8BPEli\\\\\\\\\\\\\\\/W2cX2aJbeT+IxJElUic0bOXtlNqBrwmOPRoH+B14b4dx8YMuZ58YhNpMj8XOXyqJyj4xfZir5NBx+CZgCwCp+a6BCUp\\\\\\\\\\\\\\\/AeQK495nCIm2mvK8C9QWqAb819sY3B0Zsl9F\\\\\\\\\\\\\\\/fD8Htsb7yxHygbTRsH59kH0iBKw1pTFre3gNPYaMUQEXPTe+qMto08jmkM702UdW0gsBYkBRppMT1rpG3i+J6IkQ8I4ZFGcjQwsdu16hBcigL2SHVNTiHprWFFze1dSAdiUmoTHw5xJ5QkpgQ9\\\\\\\\\\\\\\\/8ZJR+C4mtbImKo5YrTc9evoNrS+Ub7ckND4rBLXDLircHlQ5GGGXU5QP3S1sVbL2qipIRJS0FBsyrmlanUolut5g03lOhqlvMLVTwqWtV2cXCC\\\\\\\\\\\\\\\/AyTL6vPayvzjc48QJTfIe6g4rVwPSmVTesQ8nSc3nw5\\\\\\\\\\\\\\\/DdIfj5aPPRWCnzS\\\\\\\\\\\\\\\/C\\\\\\\\\\\\\\\/jGyakbK2n0lFaNY6dyQX+9I1vVpJ8XPOjBaJASMRRoi6Q17ftd1wsR46VU9DwpFrvaMhRd8pNYMPxLHanZz03yXsC87fqT943IGFg2m3f7BGLEjWhWzjwznvAB2GV+RPety+kX6PyXvuHe2G6CVhPWBQh+EUWFTu+ZM+3SV7SAw7GvqKWoK2At1h1y7hIw8eCp4KGimAPui\\\\\\\\\\\\\\\/8TkbshCOsu0hJRGLdkL8kJ87cKWhPvHbs+ok7xkZ8SX417VNRuM14VQipwZy7XZp5mhUbf8p1Tm4jw20UuiSwc2P+bMSB\\\\\\\\\\\\\\\/6Xo0pIXp6Vv9tSwhq2cMRebDZ8Iakq2TQw7Iuj7NqcdZ80BjLmUFRSKSSP5HDVjPD7SSQ12CZMLBFiu7IdQwRekzN0iOQaIQYEOw0eLmJtSyTLgDsuu8H1oduspY0tKZDC1AwzwM0ycT2L27769aFIz2k\\\\\\\\\\\\\\\/ELdoyae2mNCcpeyLEOtJ3CMht1eTmU06sdY3IflqHl\\\\\\\\\\\\\\\/c3nSgmHLf0eg\\\\\\\\\\\\\\\/RwqnewKKfTbbYbqKsdgQf+tcUAO0XaL5Rt9zj0CWmIExpP2MFCpW2MhauFXU\\\\\\\\\\\\\\\/HxLT19T2cF9N+IcSwfuNrkAVdIG8mb5JiCmsVD6J81vkGHDRvPKefD89ymvUSaW8YzY4AMzfOZl1wdbmFM25WyTxipr0fSyGqUZOG7prh15eEUlNq9w89TwzJyPoSk\\\\\\\\\\\\\\\/KjmxkiWV2Rc3LSoqXecGesP6qP45TrxoKgoexsXrBGfiLAsJ6UyQdegVxr\\\\\\\\\\\\\\\/NZ\\\\\\\\\\\\\\\/cqVYFFaMbAmQ8BiAo9hd8haiVBnda4s\\\\\\\\\\\\\\\/g0THVFL00LIJm8C9QzPs56bVdYyZVKUQl0uThvLwfHbXTMePgwA9G+XAOl2wO6Sc3MsEWLSPIAJMQzTnfKs2zIiDWaZbqq+a5G8+CHkx4DENm0YCZ7EhfXZsRM2H57IleuMLdZsqP\\\\\\\\\\\\\\\/PgBK1FQ+7TtptUKovgePGaWal8hAZ+ZGcEk+3qTI47jynqofrF462XQdwpfi9U2D3ylLX+o\\\\\\\\\\\\\\\/9rMc1ZuP8jBBdD1iCY75PJGFxpQu5gYjfX3xSNiUSyghKiACaN77KxJuH4sdv4o+2mSbbuwHtXCUSlVOLfqfxMCk59bUIS7uq6WjOoKK0FIJ1xUE4eu95HzlgrI678hMq4Zkd91\\\\\\\\\\\\\\\/Pa0CymS\\\\\\\\\\\\\\\/wXekjXTC37xBeyxpORCPWME1\\\\\\\\\\\\\\\/Qhm3+7n6AlzFcvfarMfdv+b57An3XxaIDXC2EOxDPFyMWuEtIwcIH\\\\\\\\\\\\\\\/GWcSwmwUcY\\\\\\\\\\\\\\\/FSZqdqeLoH7dIT9vBCYeAs6lJlBdZICRpulL\\\\\\\\\\\\\\\/wsHw0fcIMlZXNWa0BM4IhSE1pjzYLXcILnVMqmnrDa67vQeubY5iakxhZi4YmFmabeWJSnO7mELeE3p0s0e\\\\\\\\\\\\\\\/ogf4Y+Ixdslh4i+tqPq88408ZCYJrh\\\\\\\\\\\\\\\/kZPxGSNdkBEInZPoV21f9ggeGmjlaIvQ6DRf5Urn7CqxbyOVf7MO\\\\\\\\\\\\\\\/JrKAO20HyX9\\\\\\\\\\\\\\\/XBsv52n2qRfpJv7l3yb\\\\\\\\\\\\\\\/GMR3mShNNNyxRiLp4N7TbdmWbNBLskBAMJ0xusgQ1EQevcrXcwptipmj8BIE\\\\\\\\\\\\\\\/JqTJSnfV8hCc5NpOhl50rOuNOotUj1OAwGwd7eyIUmLqBsNkercQKeytT2yLtCwSPV18\\\\\\\\\\\\\\\/1ASnExrb0GBiYtLFoER3akmf2HVD2uzNL1GSXdH6yU9Ew030idPKkM18TgtDtRDsD\\\\\\\\\\\\\\\/KWUxiwuGdfx3qOUCignnwIGscA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022cJDiKKOuh\\\\\\\\\\\\\\\/vAtIi6btZ2tw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00224467e58fa4e2c4896ccb367c29ac993dab7c6aa2cd412b4eacc751da7b992054\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A502.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A502.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0842\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0842\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0842\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}