{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022OzrM+\\\\\\\\\\\\\\\/QIwGpcHqcXXkdIHqgoI6rbZrbzNW2FeV9CYvRYA1fGdW+RV6pRbKYXF4pqsgqg+\\\\\\\\\\\\\\\/7BBPH3hLv+zYj30T\\\\\\\\\\\\\\\/203P5zrYHPN9pG+kYjZTg1iBJTE\\\\\\\\\\\\\\\/uNUwaQK1ghYijuSh6qSesWWYX82ZA4tgj9lvXbgLc5rKyRAazylMuq4jNF7YMOz3flQdSIwTUHBnAODKb4ClJWm1YJ0yjeEAiWQadFuLgKQWVIKPrfcMZNzH3ost24zDe6nkWpK\\\\\\\\\\\\\\\/IlnCg6TFIQnaJw4gDdyo4XaNcyQVRu8pBwC2n3TR065x82IUnZkn4QKaNew2QX\\\\\\\\\\\\\\\/hMDZsO0VrdwWIhJTX2Uc67g+5EffvgjsRZdjMZVkY4K9Tup8Em6NCqOfG0D6ZfHtiNvV1Gkic7P+kAIXHPS5nUrcOJFsQ05GzCzYF5I+gS3rCGDcq6Ax2Hu4SJQvScwNEOxQNBnPjArf5o0i5tf9Q\\\\\\\\\\\\\\\/7\\\\\\\\\\\\\\\/Jcj9cNcTMWOkH3MOkVfvuUfYECfoo4YChPp868EDEC\\\\\\\\\\\\\\\/XUNZv1NCxyU64uBA8SvrnHBqByNRlNCAS5W\\\\\\\\\\\\\\\/i2rMlkaWMtkOapBQ8YI6LCu1qNa0nCh9TOcg4PLPKAHbCz9LLwvkZ\\\\\\\\\\\\\\\/pS78Ht\\\\\\\\\\\\\\\/W\\\\\\\\\\\\\\\/NYhmzxYkcMR2fc9iUjP3iM7bTsw9PMtJCb5noSsyNwu9Cld4cWt9K7Go2\\\\\\\\\\\\\\\/14tKA5+xzIJTfh0sa9xZeW8BP\\\\\\\\\\\\\\\/OXmXA3Z6jTtgUXE2nQ0ZsL11rWByH4ER\\\\\\\\\\\\\\\/fsM7l1U7j68xSO5jS70eEJNJv3Xa4QWuo25Ti538InpI8y4P0yhMIbnigm\\\\\\\\\\\\\\\/+Kww9dHVtFkTO0KS7IiP3\\\\\\\\\\\\\\\/LDbx6f1x2a2WGQr87ZQIxOQ2nfw94VHfgsj71iZOvzX6j2qDq6C5SBZ0jktdI+khCE9xBH0xnubxy01\\\\\\\\\\\\\\\/WEjYoXfWy6lV\\\\\\\\\\\\\\\/okOVhns+bpTokdmISYCTYF2ixmCFKToJk9XPCeC\\\\\\\\\\\\\\\/mGtNxreTdAcTTroeFYQTxNGQ58vVH3W9ETpCitbN6kLeTCjVXOFyQMmPRzARY0s4nS00bmnRZTMBoQivUSxR8WP1L25yQHIKgy5yte8zBq8uFVR7RBdMeDPBrztiRJdIWvoSFbA3PvPcrfW6E2X9VIZbX\\\\\\\\\\\\\\\/2dUM6Y13xe2pVqBWnfDfGwXX8p4nPBGGS024Cw+Deh7mX2nX5yAeCCahocdauOP9aH\\\\\\\\\\\\\\\/6M4VSBjeDZj2ZCn6tmO4w6+k+N3qfw\\\\\\\\\\\\\\\/aACWdLGZNtZl3Cl6HbIG9JUddvo4jUJubYIPj0NLq86At2EJ3lawSLIp1IsQAOSVOE+M5jhpZzMwWAIIqDysHxlIQtcUOO1tlg33YuIKw3Np9fS0DwkAvz25rjVC97xJQ0z2\\\\\\\\\\\\\\\/6NNB3S0ETAfOAiQQMffLu8p7qSZ8jAH3UOQS4iIDd8aZP9SfXH44LdhzM8iKwY5MyYXbfsJiGX3CYanLw050htnZbEj0BJ2sOIsrDRFo5CgW3ROglr8hknphicxD352MF1dgvLEiSMCCnnC\\\\\\\\\\\\\\\/G3GmTHJ3+w1\\\\\\\\\\\\\\\/WuETO6TU9JsZ0UGC4w9HgCHh6dcbR\\\\\\\\\\\\\\\/hRSUaP10RaGrIYed3TeKzYKwOLDW7yRNF9I8acOVoqQ04qurDXUO053SQRaXKVA5F58A7dF2XFtDQaWAy\\\\\\\\\\\\\\\/yZ2G48y1i2KPtHyLHX69amvAl09Cgfj7bz1oM3vDjWnXnMv\\\\\\\\\\\\\\\/0OdxlxmVGotl4RxDdsXWkYyO4r23ItO1a8Sd+owqlBUDJB4D2biWvwntSVCHSoh8rbbH3Rve7r2T2Vi8p12hVQJTGV0Pfv6FFHePa\\\\\\\\\\\\\\\/C6Vz3\\\\\\\\\\\\\\\/o9RNjE31j\\\\\\\\\\\\\\\/mtqBo6mDEKveGZN5IdEyJ7V+AJyYsyP\\\\\\\\\\\\\\\/275vvUf6xJsgIaHCqpKFAXsMyNGJUFMx8UrJW3iN5G4JHcXHFmNcgKdb\\\\\\\\\\\\\\\/6GCe\\\\\\\\\\\\\\\/eUNd9QkqICcVjPbksGCnOFCesmUe2DqMp9mN5t8poXBJPq5cSZg5lduTOMQcVEmF+yaKn0KOjoHdYcxSpV62upc\\\\\\\\\\\\\\\/ibfzCarfwGvuPxJ07XOet2EbY90+CmHu09pxg9KvfjKiUfPuRhJ\\\\\\\\\\\\\\\/Z1B5f+kk+EdQs+VGcbqD9p59T3XLn7oFMvE9B4OYAZeMgbc\\\\\\\\\\\\\\\/ZPdVYHkLQbkMgL\\\\\\\\\\\\\\\/5DcxfHn7+hA5eJaeUcxFspiNE90imEaHZv04Oh8dYJbjLFEWLOllSg\\\\\\\\\\\\\\\/EXiHQ2DBOqnohBNjOhz6f3AJ3J3K4eCMPehA4dj7pyR6xgqt9z2j12idSnSEfNPX7byK3R1iVQYjtnB6KP9RA0tG4SWLhC5gIAxPyQBb95FWFCkO2D2nfVv3RBS\\\\\\\\\\\\\\\/dxdFNDafprNLjMrnFuqF64SrWU9JGsEjUjhbdvIRkUk4wALnH6EUhBUHbL0jWtlLRuX5xdT7yY9qMNLkOkXyg5wlsYHY3d9boU2KrhGMvEHarvfX1T8qjtP5OEKaHMfSf3wV57Ewd0p9WUXIK285ouqGTel7s6HXsh1QFaBJUcRpgGHAkP+3MMqRjtEUpRi4HHAXrbrb7chbBsl+VYP70lG0KoLOThnqvzvMHoAEBVxiP9rX1Qn3HFgpPgxbhu9fkSZ3gtvy4Tvg3YCnP48QtCY2EMfEMDU0BccT23qNeCsxQYfvAnVH+t7hr7tvzIP+pgncYPVNg3H\\\\\\\\\\\\\\\/skYEdMpXtV6wUUpWp7xxGSVZLH9LY68wLIL80=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022JMLYKAjtsqfV3LFDgVNxsg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002200cc42addf701841aba3df6201869e0d07e83bd995b3f5e2aac7663aa39260ce\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A7.3.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A7.3.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0014\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0014\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0014\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}