{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022xTYhiaSxqeVKNee9oP34uKN+laXGkFq76ukUZSqUVlhDZzFAjSLNiU07DhslRMqmeAM3nEr\\\\\\\\\\\\\\\/FVruivRsyvtLUf1mc9klwUS0KN3mWPC9OrxYfZYfS5deP\\\\\\\\\\\\\\\/F+U29B1h+C828qScA27IaM\\\\\\\\\\\\\\\/yl53oQIAOwm0GW8ZJoy70Ikct2eyquik3NPBt0vWnDFU+unb07+R05e0XDwIXXN\\\\\\\\\\\\\\\/2afd28N9KKtM7060FUHBaMjlYHqtYFSuQEhi3VI8\\\\\\\\\\\\\\\/lW6QTrP\\\\\\\\\\\\\\\/La3vR1O2ZaObBH8j5PYaK9\\\\\\\\\\\\\\\/IuFD88U7qDb1dNKMjy7TbCZS2KnQKwA6T9PB8BKuh8z1D8KSZ+Aj52LbXHDFXC2l5XSDLnrhodzgFE4vH3xIpc14D6rx7KHgd9X93X+aIwon9A6G5rI16bfMJNNgHmrLTq0qnJUtf5nVzW9XahfFUmJESxc51H\\\\\\\\\\\\\\\/20N+pQvsaRsSql3XxUTNwHg3Gb6\\\\\\\\\\\\\\\/nKL2EcZ8jkUGdQ6F2Z69JMg5DDDte7KO5jAoIVo9NSjdtKbMTL8e+yzaYecxa6w1D8+VESq+mrgWdz4jQgrqpMzbi\\\\\\\\\\\\\\\/vUN+VutLT\\\\\\\\\\\\\\\/7WpBjPDu8F9f8nNavcpyL0LpSodjXPZJQjG+3rnAob\\\\\\\\\\\\\\\/sHNctaG980WeMmvpJcHvu2VILK6dQnSqhOlWvwA4g52Cn5NZ\\\\\\\\\\\\\\\/eKsreMEcWJaRiYgyyQx77ozbgm58fj9ljg7GoYGWDm7kRxeB+9zYRwXg\\\\\\\\\\\\\\\/JTlPZnK3mE7aLjXB2hxH3+XTEV36WmYGCzeYvAi\\\\\\\\\\\\\\\/N2BjibjUFqK8RR4OzqYDgmztdi\\\\\\\\\\\\\\\/JEiepjSMOKnyNWX\\\\\\\\\\\\\\\/xfppnxaMbkBN1ySaVrXEIktupAitcI+diw677Mnsr2igzeLXUBLmKthQgVzzYztyHQCh1BiIHAUSVaSuF0wJXxnLvAmDQuazqm0eh4yfip15rBeuYcMl7ol5Kbgblj0BL5JOERTHcHf1qm64xTtR0kCGskS938OWi+SzEBIYOMgnSKDVgZ5ePtSxtXu6j8WxMXKU0nf3yr9UWJXU3vZDe4cL2Mceirc+x787ITDEcX7TvC+umwjUArnA9tXw5wQgJMUoVHk3QAGwmpN8kHIWKSffE7RZ\\\\\\\\\\\\\\\/fbRfnl6HaPOJBOehoxn9shag2RdhsFOlN+OEi9gVfp4DoXtKYdOLHRAI2nzJyMp6+YHIeXjreu9f9IE4xpdgb+GDuz8i92i4AKrNG2PzO9xMbG2MzxcRfxa7yQfyrSlLrYc\\\\\\\\\\\\\\\/pgruBHdwf\\\\\\\\\\\\\\\/93Fb1mitF0McM+3VPDmHNncMglkCWLA9I7vkmWilmZxon9GwtNMZg6mfsn\\\\\\\\\\\\\\\/pjT0bwR8dAKxJ+QO1+SVecY0qyQHj8J3iLlnnl9yc32qvdh0dn\\\\\\\\\\\\\\\/ysq+CLOD5MLKtlCdBgkN0mqGl1\\\\\\\\\\\\\\\/xSkEU0irQtRTwvWqiYgD0M0qLr+dsyC0iRkw3\\\\\\\\\\\\\\\/Z5fASwxIIms9KtQi6jMdcHAtgsXbw3Ng5+piiK7mGHAfjP6QQvSP788AuUMIC56iEGfeK295Wf5C8PZeWuvQIG9tAuL\\\\\\\\\\\\\\\/TaOceA0AH5Uw5sjCgC+bETqrt7KV80TSQzuxM8O0sS26FZhVV4U2sSS6DxT0wd5jfnvKWG1ai8Vsp4aPwZYETTaxAZumJSjMvKo0VUH8BOzGamdrUBwHBiK3avHSBqprAyEMT2Tmn4V4e5S88Mo69m2bvE5X7CY9OZj7KQXoiOCIQFgIepedvxmNQxfVwWZtnAGceJ0QVtZ0SmHHyc0o5M30Z1agVp2Vft2n3iSZ0dnhAR9m7vklJDeP6u5AuRBvwLCE0N\\\\\\\\\\\\\\\/wnK+DcMoJvubrTzJpZ51e15I\\\\\\\\\\\\\\\/gA++ZlAANVtOK178C8p8xTInVw3Xp5FCvaxgjcUq8iAsaN7DojFhyClEiidsgBNK33zrK+0Orqc6I270hNGu0mBhS5VeokYbPnv761RZKlNlBaJ4QMJdsspEFiJL7hHBc0NGUJFimK\\\\\\\\\\\\\\\/vKKKr\\\\\\\\\\\\\\\/oOVJtHJqExa00EUx5QiEe6bXsgp9VZ7Is6\\\\\\\\\\\\\\\/EUJjKUC64FWlbi1UlVk4CxfQzrO9hGhvDd0z0pXVLcDj6vVOMKHKZul6tf2JDka+pVR9erpfrgss1x8TzwetoL22Mr2f7o59IW3TGqRq7n4JP5v1LAQhi\\\\\\\\\\\\\\\/t\\\\\\\\\\\\\\\/LxrBBuWqPnfX2GL2KYfALqsaNEF\\\\\\\\\\\\\\\/Dj8lZ6W37lqB5iWANIp5JEGMTqfDCkHXUNiDHO93Pf220lhdGi9\\\\\\\\\\\\\\\/4M0uAPgy2IhMI\\\\\\\\\\\\\\\/D42MeO0vDlDewWHcM7Ft4H0Lezoy84JoBSWruB4hByFIa6VoXgMOqYEsVh8\\\\\\\\\\\\\\\/AJ25dicuAkJVQo5+I6teACy03V\\\\\\\\\\\\\\\/TCTgojBxaIWHgDnwR5J+W5Fczt5L+zJTq95ycjN\\\\\\\\\\\\\\\/p4\\\\\\\\\\\\\\\/XpZOoPVtXc+jEapFoYitHtldYOcj2p\\\\\\\\\\\\\\\/hrgZ25++xw07fiVhHeJZI4oLkMrdMPQwQ7JXUNi+60MfeiWFU2fYYQBjl2goNxt\\\\\\\\\\\\\\\/6oyacAtqQRm5cSCdJeP6mm9vlapnYbSPSRNt\\\\\\\\\\\\\\\/VOpViwI8hx5MOfb8nx7oUoa+DnaNdB9ZKbMcM0azxzWMoDBW28j\\\\\\\\\\\\\\\/ytIdt\\\\\\\\\\\\\\\/Z1DOoLGbpkekSoVsPnnTh3Q11N3VLmgi\\\\\\\\\\\\\\\/HvcJT\\\\\\\\\\\\\\\/7sAOyOMcDTgCtgKf6yuDdv++nVCYwpnTUysYNP2AYQCuT2bGzE+Py8SviCR39YhY5Hjv02GQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022U93\\\\\\\\\\\\\\\/jPo0JJSQX7j17fcIXA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221562de1cb27ce7f260eeb7dcf7846fb32e40609d9fdd20d8e299ddb3a385bcff\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A161.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A161.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0270\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0270\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0270\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}