{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00223FGXsY+J88cGY1tTd8vEKknAUpGGC7MvH7Z1fx\\\\\\\\\\\\\\\/SlprKgVutyh470XeBOrutlfM6PFjYKDNFmR2RU3f1dEh\\\\\\\\\\\\\\\/m12tW4utsEDNa1T2ol+XHtJRsZnRFNYGTZ5R4eFinYUUSgY+EX8mFFqjcoN2fSlkWmE0\\\\\\\\\\\\\\\/BDduFKNGrB4uxCIo7RqSnM7kpnrgc2UYn4uTMhTLf44KjmXmrJ81kM0iPEJqN77C+A+bfTHUls269TilqDlQ1QSrEgQ40jlWQU5bmnvPuRLWiuABacMnVe+3qdw0cTe+Kc2PKZEvXD\\\\\\\\\\\\\\\/bEMrcYtGYw\\\\\\\\\\\\\\\/LFGKlvkOCMby\\\\\\\\\\\\\\\/PYkEAOBA\\\\\\\\\\\\\\\/6kbZlUxql698nXSytdxegw1RvB3S+vfsir\\\\\\\\\\\\\\\/eDl1\\\\\\\\\\\\\\\/mLMVtrxVfUCqwWey7+FK1hdNZni4Ju1rlUEfRBpkSGjNV9DJdKO1NGhRZ8L15ytzQ3HiTX8JTDoSS3d7axbIM66SzP49cYFGLVq54lVT\\\\\\\\\\\\\\\/0VA61tGAdJTkdxGxsui4Kj8QJmpUzuRK\\\\\\\\\\\\\\\/s45LCg42cittxFknWxmjOyyVQxp3Yrl7EMuZqxWuTQU2QZibF5bn21CT5CW2ItEIFLxKSSuRhks9X1sXxbvgI+wIpcNdrYoLzgxDg+bdaD0\\\\\\\\\\\\\\\/tqBWOd62j9m+hBm+SkzfgBGEmPyWIkzIUXsttvYQ+u7lOmHlvLwbzC6RNcjEsGZFIY6haeMXCUA6uSBaTj+xouqealX8pEMH+U1dLTkgUK2uEgHWhFoLRa7VDrd+rXKtbqqa6K7QS93WLNQbVufyG6NNvRHF0bd\\\\\\\\\\\\\\\/dzsSGDzgLPEj\\\\\\\\\\\\\\\/DSA64AwnC4Hay6eGt\\\\\\\\\\\\\\\/Vn3Wi4TocEpuV37esR3rskj2VHa+X3y\\\\\\\\\\\\\\\/o8f\\\\\\\\\\\\\\\/Vg9B\\\\\\\\\\\\\\\/Kcab2XIN29pGhBPRygXHf0v06qwzV6nSU\\\\\\\\\\\\\\\/GcaqVrYHhbufGFoU94TABqXCl\\\\\\\\\\\\\\\/IX536c+vVxMqezZXTqczbBwpwJqFn6BlQTyX7YEwZMCB6uE3+OjtgAjiJvF3XzGp3YXo99bmEwj6EQxI2X36CbcYotmYBjeYCymOIKytCXatmgE3rs59GoOHf9ITy8xq2DEQiiY965j2+0C9E6yLA2vhaUxGFOTKTYirI9h+TVTe7imfBkWqL4ZyWY\\\\\\\\\\\\\\\/zqiUlK6gsKybqS\\\\\\\\\\\\\\\/BOXiUwGPdDwbp6NqewGnWuE6d6inQkB3QQgkNRELimy94lr1pV27T2pxszobbgZF3ugWdvu4X+tvVe6rt8U3nzW+MncbdMWfbhwmvLqohy0U+5Q\\\\\\\\\\\\\\\/XFlGpbdZSfqRGWWoGZAcuIGXAsssz3dOYVVQzejJezHOQvnPjaNGdSPrfn+TMr+O5msC3Y+ebdEGQdJ3aDCMLEF\\\\\\\\\\\\\\\/DmAz4e6ZM0pVmMQL\\\\\\\\\\\\\\\/qnFWAzVrxqxFquN2Gg2ghl+Lrr+RcjRguj4WWWG6JWWNjtyNghMt5wZ6uEnMuMv3O5kLujFiw72jHXrzuJRfy57aEY3acsDaV43fWJeeT6g\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/vcsp61owkPRr2gXNMOprDOI795LWeJ+VRF7qN72vEA5zCNyYTvJHbJCG1y9DBvwruDMGKJq4KgNtMvl3MSGY9LhWOcAkasZy3myyUnAV66O1ge+AXGio3pyd\\\\\\\\\\\\\\\/Gf2e6aBj8o3ppn1cv4f+UkewUldiugaP4Wxjcq1WXdLzQR4AnJOnxObiiq9TFVTxo3Ft+yfXLItxKVi5++sXGKkwLjy52TxEziCWUyZT4HsdhUeQC1ZuRTwP8BtrtCacMRvlSg2OA90uMag6u7F2RO64soNMZPId8DWMhpBDRCdypEpzEMbymyAs\\\\\\\\\\\\\\\/E7wbugAxFDnKrMoPxZpicNfeaesb09HV6Aj987fIhmZedDSe670VntSszry16n1PczH4M7Jw4YrL3xQBh8jzrzXZ+P0g5wGUvFo3\\\\\\\\\\\\\\\/OOj47DeQ1Dczk4n5d5ZIcoC0qhhmdGXRZGuOmKRuol9XSemvre2rOpijWtd1aq9AHgqKJjIF5LsE4ztkPH2FIX6KcQCLlUwbKl05UPTBYeZn6rjVCRKnYuYxJcTHk754jvtEslXkokFZ1inzwLOq64gi8rwDcyYjZxDpsawfwU\\\\\\\\\\\\\\\/yeLP0xSijAwyUadwFVO1P\\\\\\\\\\\\\\\/bteiV6w4xqViH3h7G0Vy9TQASwg+TOqUJRJZ71sh+ASY7obI2NV9F3BrlbZOqy\\\\\\\\\\\\\\\/m7feff5Er7wgwgBnltebOL0FE3PXKvvaYATE9at3+7T5GQa7vKXimJoFDyhlKEpHwDKGT49IiQ9Qoz8\\\\\\\\\\\\\\\/X818ozYEHJZk5GMmDpD8iw58VhVOEIUcV4KRraT5uUvgBIUWte4mvYfiKcNDOgByICTr8TuH4D4RUumm3MzU64nHEgfmW6G4cM+X\\\\\\\\\\\\\\\/1YXef724N1izmM78ANO8N4jIZlFV4rp8vRHivCv+UkuZ9M0YUUasXAptf6BMYMxzl+RSz17SFBs3ZUv9qEHIq87tUo2fLP\\\\\\\\\\\\\\\/ow9gBeKGbbri4ddzSKC+CLpFepfIa2dgZtbMLwpannPCYNM5KPHM9yGChYsTpp4BKm9yc+37WSFtLHsX63bNumaOe5xYDfhBTHwHF+BGHuxr+d3ayh1KI5kyZWdKnFXmMkhkNXDSam6zR7AoonbDBnX1WDj\\\\\\\\\\\\\\\/+Xx3n5BxiRkDODIGqr4gF27YbZ9KUIzs4eMqrJWK5Dk\\\\\\\\\\\\\\\/zxnA9wep7B3B5GFG8Cc9BKrjTOSrr2yU0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022QxenKxid5P8S5Gf+Kx4M5g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00227c8dfbdb410b105dc23385051c0a984b27d83c05e4ff7d977a2fea46a012b861\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A506.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A506.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0848\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0848\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0848\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}