{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022VBlyH7FdYLnEtVbNfxkAM85tPCf4APBRGHpqkRyW8dv\\\\\\\\\\\\\\\/muVPhZCCw7nYqNH5fU8B1QgjmURBmlk43JbztWNYi6tI3jq5LSJmea1iNSpyquwr013+4R7w1\\\\\\\\\\\\\\\/Tu9ChGNh5tRzYAM5oKSAEiJgTVhxXXoYkYIXwvi\\\\\\\\\\\\\\\/ftEe3jCQYXZlAEK1Y4HJsx1zdpXIAO\\\\\\\\\\\\\\\/7KpyiIdh3ITzAWns36RkYk56RUVZUgTA3n1YWVRbNZflw0sN5pw4NhBx\\\\\\\\\\\\\\\/tfxtaD1rASIMuB+dbezcZZSAmzXeDElwISwRU4nj0X3g3\\\\\\\\\\\\\\\/q3MiIx5zUe4nD40PKgaz9nCmx\\\\\\\\\\\\\\\/UR8QVZwrZs\\\\\\\\\\\\\\\/3aghXrxxImt9NF7Ut65eqnamy0LwGzbULRx\\\\\\\\\\\\\\\/yP8MHChPNykNmiWUX3zdJtHPHxiysBp4AFvy0jlpmJiIVJk29Bck0RFPHFJQsp5iU7ZSfwC6w9M7LpL+QdoIJ9P7HZE71uzvm39JWKLz9Tipq+hxbKr0YhaOaP6FknZNtgzmD5nr4\\\\\\\\\\\\\\\/Moyd9O2uSgz5Zmc2fze4YAnun7jq04PK1WB4859O+MpTBbm7lHImy0LTt3NByJZX6QZp22tKZwzxYB3PCnVkEgR324OQget0GGfQvr9TNInIoIKd4n5YPXP0056XIedZVwhfVIUfVZhs\\\\\\\\\\\\\\\/fCfUdvDXhHyrHpfJZdXVzS5uHmB+Pm\\\\\\\\\\\\\\\/nY5xumv878E\\\\\\\\\\\\\\\/7On7BsCHHlZHGTIitRQOkSuy+xXryU5yRBKpQruCs8wETxo9U9Rslwiluc71f8HLGHLUahlJE2O3HpyrlpkIekot2iNM+hfL7zZ5RO6tsBJk\\\\\\\\\\\\\\\/Ri9PM5560o1gHsY\\\\\\\\\\\\\\\/LVHz\\\\\\\\\\\\\\\/DShE\\\\\\\\\\\\\\\/AzuUUR\\\\\\\\\\\\\\\/ALNyLZf5nQoMYbhbfXDNnuIezBBrHydldyru0Fv0FSrw9Kfjjx0u7yzkIPh9yr\\\\\\\\\\\\\\\/E+HZRocF0PaAj96cRf1fd1BTh5R9bS\\\\\\\\\\\\\\\/dmeF4sX\\\\\\\\\\\\\\\/Xke6alij1wgY12lwJzpwMa5hHsNcmeBFtgoKIcmc0NRHEMWuZ1KfL30SryDQYVuYdms3I0J7DRmlHzXtNMilAWh2W4tV9+nMPlAToZjv2RLX+LdbaQZcAQwFm9xO0RWCx6tARFAqLTe\\\\\\\\\\\\\\\/otkhZSoWZUN9jVqLNaUdGn9jHiW1lAyGb1LpkyDkHeoRR9rEGv+9YQ8rXx+rg6rCSDKbo6gJ6RBKRRu0r+OHJeOhW0Vov56dCmA9PExAIH6Cd5aYclpwBd5I1U8VUWuLzaNqus0CJsTs54eDzE4wgRNaWpzYGLV9MKTf2NyUA5t557EmYZ+mSWEi3LUTYtCzdQDIym5x1+fzsq83iZw26wQJhCj3zgPOjhOd6WyDhq42rf1re6RzCclrBzpbm1zryoU8Y12QrGfWPkRzmtrqBkmYe5oRUuS0Py7S+zVjdKwLvh51O6+nRqbIqI+inP45TOkzZhUv0V9tqNdLxL4VMkBtN0z2Ik2BA\\\\\\\\\\\\\\\/uv3di0jHSW60yRMwtkUiYqzIRdiiYWUnmva32WG5g0dtGEqntcJ2oivxeUTtV\\\\\\\\\\\\\\\/zxxShJuGjeYF+2M3NhudS+dX42aXN4lNFjufYj3PoawXU41q3hTCGr\\\\\\\\\\\\\\\/TbVEXUhCc\\\\\\\\\\\\\\\/E8uf5pvPrAvyizK8+IoxoKvTAicwrLCeXA6alMeji1OHSH5KpZkvIe2eOAUDfkVdOc992j7HXhBXJbAEpEk7\\\\\\\\\\\\\\\/lBuGqc2\\\\\\\\\\\\\\\/UzWrRDzk9Ndvl4sX1Y+zhrCa\\\\\\\\\\\\\\\/zcn0cIyT7JlAQiKzytGeiJ8sXegBmdhAIMDOKvZRQHtHxYjWdMPyFE7AUKQBtI6ivDEePvFVVLfFPgRvqUiktrU5Hx4VzAc5KH7xWFADg97+iA9EozFQmN4o9o81rdWKkrGy\\\\\\\\\\\\\\\/XqwzQQVEQRB5dpNHzc2emiwZCx7rsnmKFBvY\\\\\\\\\\\\\\\/7qLSxjAJYjoqs\\\\\\\\\\\\\\\/VuHXRXshQGoNqh\\\\\\\\\\\\\\\/St9UVAJD6qlOLIv2NNcqKZs2gB5xlYdOyvrTc4XWVDBiE77sWqtX00PzKc764Nap7dnh2fhhbqx0oLGHNVQDDlbQ0AQuLm6zwOmsMlE3GWa7YQwsu+U0r+JBHYbP8c0yrVXxepJxpvbrhFDfxHgk+hPvrJEXXdapE+2dL517xQkINzigeBHgvM5fNqXVT9ZZhbCbgeM8JkbXoP05vdh311G\\\\\\\\\\\\\\\/hHQlCYaQJulNd2Sf3pDOcTPQP0Onf\\\\\\\\\\\\\\\/SB4dXczKlVWoipzq6zD\\\\\\\\\\\\\\\/s+ndVOTi0nAmuhDzB6SgMJWJu14HDDoGgL3GNGhd1IX0dRDCx+6dsJ+zd2bD\\\\\\\\\\\\\\\/iO+xNdBZ3Pt12m42JCcJFP0i\\\\\\\\\\\\\\\/2q3S4GSW2JpWwnO8f\\\\\\\\\\\\\\\/SqeJeC9+mWSYX4bE31ClxoqX9CkMzvtw7zURr2TWRIN4JEDuyezWaMbl1+\\\\\\\\\\\\\\\/sM7oHO7KGRZ3mmaz51VioTwWsKX9kTg2R\\\\\\\\\\\\\\\/bPUqN16fi12K84TweLpF4ABHQ3MmH2xs6MivjZPLMWuWah0+X\\\\\\\\\\\\\\\/aa+av0dMlY+P0rEXcM0t6HVtOcjF2pNSuaptbvGyuE\\\\\\\\\\\\\\\/FwtDXIyEWdk3uNg3Y7G\\\\\\\\\\\\\\\/WXuQJb0QWv8XSCMh4l861Xh+atCiMb\\\\\\\\\\\\\\\/lFg+P9qLc684NkWkqGrUSYy6WkOinX3UAfTFkcJmEPnBQBzZKbAy9voHQ3VmOYTowY8fdi5dF23RPTfFIZhJ+Hx26uczWhido09yKZiwSwSAKR707JcGa+VSh6FMTtQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022pIst6VTTuuKDOW+ErmEwWA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00227942699b6afa1ef44d74cf749367673ab886091a8b80dcde4cbd0c85df0fb934\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A257.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A257.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0422\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0422\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0422\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}