{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022AKCQ2e7FEKqcSMBzLI7xg73HZXLMQYR5J4KYrtF13XyRTDVYOocDao6DY4hdCIg8P\\\\\\\\\\\\\\\/FZEciez5HQnGeGyxon8TNxtHGZGbRQ1tDdlfc5lP4Yq0XuGAPmktfV6TJagNgkgheLLvL\\\\\\\\\\\\\\\/o645NXOiiRFfScv1PODyVUzXzuKiqxzO4dkkrYUS6spBGEepwyOsTvQhcOHe+Z1LpOPqIxtWK28H3JexYIH10kUbWPipDmoCVHOYN3MBBOuK6jPvXK8Ck\\\\\\\\\\\\\\\/Usa3Dc2gMs67I317p4fA2Lq8egxowhQYksA1N1F3XPsUbiy60UVs78fNmxUYOL6Am0ixE6ggPo1wFQR+7EPuug0GsNa+DHMN0rqSqpNsM0xFQxsKqXca8VzwbAlbTkNgczb3GhR4gKKUVBqx9JeUJHRQ6pi0GJ0czJQbJZBnbyWFEXPBDmjyrSy0vB5bugT1XHa0mabCFmmHhJluDi4f6fQp7ORpFsqw7\\\\\\\\\\\\\\\/Xn9h6XUGS5+ejZTpLK8gs0jwAQOOlxOd7VQBIfYg5KOiceeSJz3ZX7wzec3bHfLxt8zcIFPuB+2REbTWGme6979AJ9vGmU\\\\\\\\\\\\\\\/UQbzFTLhMmhu5Q2+cfuUwW4duU7dN5JgMITEgrtJJAEOYiAzFPrb8lDxmyabM1QvWM5VKXEPz7EPeba4UF+xSYmZvsUd7FR2QaA\\\\\\\\\\\\\\\/2ypIHcFgnKRiZjRlvozlX4f4Ue1l5MtJ650yMLeWGMmb\\\\\\\\\\\\\\\/yM6fEJPwqp4C\\\\\\\\\\\\\\\/9xpKy26f6OsMnzlFDoIm9Nir3SiyIWIpVuYdKFN7+zsjJn3vx2k83LiY1OVyRJ3Dd9SJw1F2AKf84ffYl+kWctuJ7zIEPAUsEsu+zFXGC8i9fuWDOs71\\\\\\\\\\\\\\\/nBR5kXW\\\\\\\\\\\\\\\/au2oDmpN6fhIkMDJ3ZQMsD9tUFYKgFTwXOrd2w8+IUlfSYOJOvgyVNqvWEVDvd3ZMf\\\\\\\\\\\\\\\/bZ3ePheE\\\\\\\\\\\\\\\/vwOhTmwoCmV2D4PwBtUnDiZkwxic1f0wNMyNuPDyuMvJflJxnAdNm+F8e+y4jZMLXAp75QGBUMrnmfwPpqJVXOWFuk431b532mqoL81VWmyvIXYz7D4sy142TqtSc8\\\\\\\\\\\\\\\/msaAjIn8tiiXV+4a0RJAwGHUnJYjH+EMBfEHJBjwF\\\\\\\\\\\\\\\/6BDAO1fQtpxv1DdynTNKbnmYN1yhniMFrUTbKyEB8nP64fsEhW4eHB8kbe89B97kKo5\\\\\\\\\\\\\\\/1ADtxzDDM928bh42L+IqDB9M8RpbG4jyenyGJuyRoClo52ZrQIxXl65KqH+q1iPH1vJ9pISm9aY\\\\\\\\\\\\\\\/mnr4QSSzDKtBj32gjiyL2ir7aKMdSuq2qvek4Akk86FRTaXU2qZs08oJ1qTXnjaB\\\\\\\\\\\\\\\/JwZA6SD\\\\\\\\\\\\\\\/O2gHwwtfWgR3Xpm\\\\\\\\\\\\\\\/H159wsg+6QbUGcBFU99ZnndUUxMO+lFp5eEucvQ\\\\\\\\\\\\\\\/J1MG7IAXQ9VgPjc4eMs92CaH\\\\\\\\\\\\\\\/NpCn71SZGwoeKwDXLx76ljXqFeOGhEuEqNQPqhU5BIgGdcEmJySV1dJsLX\\\\\\\\\\\\\\\/fTaCOMYWD\\\\\\\\\\\\\\\/S8knXbu5AC5fbAt36rmmV1FZ01SEwuQTfewcFs9ujUU9TdYcUcRazQJpqIeT5qI3jyzEeOFDR43sDTudNk55BLXLnKWY0TuD2bA+y5r58egrmcGfTaB6\\\\\\\\\\\\\\\/EyVIBKCG\\\\\\\\\\\\\\\/DC2LNR6Gr\\\\\\\\\\\\\\\/nNJvI\\\\\\\\\\\\\\\/fN\\\\\\\\\\\\\\\/iY8DBY6VkJs5xNb9utFOYLeo9G6mvo\\\\\\\\\\\\\\\/wbPUHoqW6HPB3IhIenU95sH8Hmqk4BxEQWPd0ouus4XmS05aOJZDF4djb7+vFt9Ph+YzqimA1j6FtuOVSoY\\\\\\\\\\\\\\\/UNFG4hV2QksjrBjU+ZKRy+rQrTSDVLGSrUUNqoVvhJ1HG3vx7bfYMqc7bdfl2cq6dJWuzy+EvFtGQTNsHT8T0qCv7+gxtql52SCvFWjXNt5pldSxbtFBw8hNRMJlCjOXFj6icUVGAuhJURrdRO4YmRB41kW7nFqbBVKU\\\\\\\\\\\\\\\/+w3CDZDMl9rhdLxLEKtwppdSkbu3tg8I78Vd7cfu448O83Bti07vqeFYUh2Xj5w75w1GZ++jlPDnr1LQHqyFUn5kfeY9oAsJ2vEvrQLRF+fWMtNHfkEdN5CaGIiM+wqjcq80\\\\\\\\\\\\\\\/DB\\\\\\\\\\\\\\\/qXHUiXsvDk7c9RPwRfEoCDiT7k\\\\\\\\\\\\\\\/MuK\\\\\\\\\\\\\\\/H8Ow+xL1pdTohRJ9tg2rXMmwaZxjKKDYHRBU63oHNiCcRQqzLzKHnKAut4rzN8QT9DjpPgLepAN0cvsuTglSc+sJwBoC0c6vrE+g8DsgsyWbjWEA3H\\\\\\\\\\\\\\\/x9PH6m+wJi8SeS9SwvWOpGnuXFRSTyGcaVufh9mJGa5QHMFFSH\\\\\\\\\\\\\\\/bNN69XkLGxRgsE\\\\\\\\\\\\\\\/4ifRghf+1A9j+jtTeC6qMLsCHvqpLBSiz5ahu9mtppGQyPvnTwtcunT9h7TAzXvDVYtIUb+dD0U1h3V+wmkCfVtP7o64QzzVVkq9nZZ3IsbHRr4MS62QNDkB9O5h4HtFKucOOJSNgtEVXJynTT2PUUDIvmFu\\\\\\\\\\\\\\\/iAQxzwsMhbkCuR6nylWMnHB478k3aDWTzhKYkJ7ZaSsSYO9xJ7Z1pIvFRigF\\\\\\\\\\\\\\\/hbJJdxfrjb9fkY4NlmP9Or7KHu6JaOOJ\\\\\\\\\\\\\\\/8WLcVDZw76TF\\\\\\\\\\\\\\\/GUr9zfvz\\\\\\\\\\\\\\\/puOSSjlOz+jkDAZ+zphtdV+COt6b5e71WfgNJ5AetmRPi9Dw2G8NhIzk6yH1lTEtqp\\\\\\\\\\\\\\\/+nTAQ9T8mkSKUDp1d6Pc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022BjjW\\\\\\\\\\\\\\\/jxd8qhLIXn85SUVBw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002293ce4f32d3b4357b2bd7e61c0df589b7c917b1ed276a51f5c0ff553c24186709\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A108.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A108.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0181\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0181\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0181\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}