{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022VHc+fp5cPkjFLH0Lw4n2z8WgrVkweYgQoJ8jRM5rYdc\\\\\\\\\\\\\\\/BAgVp3PvcxRgl5XH\\\\\\\\\\\\\\\/Kfn4qmy48Q+r0OJGMOrik8GaAQShu0Gg2vRhsexfvFOPlDdOOcpIbcpzj5xCiAaf5QM4LcekxbNY3B4cHxgV3CB7KicBza2T7Rh9VdImi604WoO79IccrnViFqvmOPeHx7gsE\\\\\\\\\\\\\\\/Hf0aMzBxnvy5264e0485+TFBBR\\\\\\\\\\\\\\\/TxujMSY\\\\\\\\\\\\\\\/6L7LTd\\\\\\\\\\\\\\\/rto5765OU\\\\\\\\\\\\\\\/c4dpjj0h9mlm\\\\\\\\\\\\\\\/HUzF9Upi2LnpZgBNnX4l\\\\\\\\\\\\\\\/L2rxuDqO7AbBvwKg5P4ubwnmQn1s8OjL3Dab2e6EV3XH5ts4C2NA6ZA7587W38XIwPS5DN6+eLn9hACe6W\\\\\\\\\\\\\\\/1\\\\\\\\\\\\\\\/cz9CtwMVYBiq4n3k\\\\\\\\\\\\\\\/iIbTBe2zIG\\\\\\\\\\\\\\\/H1BkzNkoQsxxXvGnKOR3RnSx6b6wZte1ilNI0ukDK3\\\\\\\\\\\\\\\/WGvivPs5FUimACq6Y+mpC5z+Ro6KXPdbPzHL2TpvsvGl\\\\\\\\\\\\\\\/HO0ECl4rqG4GJ7\\\\\\\\\\\\\\\/4fzd79n4RoVFjuvonxYOBxRdbgEq3dJkONSm\\\\\\\\\\\\\\\/XbQIZOdFCQHLETBMzhvL1FaJ8QqBIj1CrwJnz4EetFp2TUFqkhe5sVpwbaadWY69dvA19cEMThGe89DacUb9LbJrMtMKjVrV\\\\\\\\\\\\\\\/C4Xw6QOFG1LFOVRi4qvHvyGcLkg7yiK4JpheOMwP1ppztAfWKRX9UKPIvHQ+TfHne\\\\\\\\\\\\\\\/VL30\\\\\\\\\\\\\\\/FzOFjfE75TbZiFSdILIVU5cZnGLjeRxvqE1XARBYiCqpL8E7Se01vvLcOFcoXPDSmegpColRP7PI4cAGN2VwrsHZdlcRZpJ3EmF\\\\\\\\\\\\\\\/ycGaT7yAFcANKeUUsCm1G3zR8UT8kNEpm0F\\\\\\\\\\\\\\\/BEsM1lLrM8uOnPx7zEuj4mLsKQlWcIS80NgnlQZuKj4UQ2MbEbdllvzYEItfyvgMno5s+bW0q974KT\\\\\\\\\\\\\\\/CdU9\\\\\\\\\\\\\\\/MNCvsq2bsDHYgOTVEMwNwI1K6EhGPsbsNPmAOJOUkRMYoSWsgzZZpjsnhgodw0YGoFO2kzA3rlP2+RcHRU4XW0c5BZNN1B9JQszWw9iv\\\\\\\\\\\\\\\/6no9Ial\\\\\\\\\\\\\\\/lbrZRqSQiSogMAE0Y\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/joGp2s06spDu8tyuf7j2FJOGFGq59wKyf9NfovaMrGp08VpahLAQ3xLq3g8TKAaNrPCWl2txehEWYPOH1kKLeZz1miDbQx9n+bFKsbyh5AXrvbZiVm1wwC+rF67ICk64k2qfKjYWDGtM6KnGKrz62bUKtADIfS9pzspRHH2vFRsAN5yOz0Jj\\\\\\\\\\\\\\\/+5G9Vt+EN5HkZGpqsJulRcdJvXZtInsG92rssv9DINqLz2\\\\\\\\\\\\\\\/WW+FmxOEC7xveoQ2K1KEU09UEaTO024iNz\\\\\\\\\\\\\\\/84ow9eCP8eSsdW4AZ3I2vmEB\\\\\\\\\\\\\\\/htqgtDXPD2aYV5CCv0TY8yo1okD3qhfuEn5ist+MtNWfB9MIWBjdReMMIAM0R5p9Fg\\\\\\\\\\\\\\\/xMWyOZvzHOVId9xBgi0bIWiTGzcPYrddAQ0tdsInA5+P0S8QdAFW42OUBsXLsXCmr63KFLpxdL0p8x9Ol4oxsYCT340796kA0r6ZqRh64DanTJA8Nivb6hZht15dKMMDTNoLLYI9vxq3QGDa3eN8rUcF\\\\\\\\\\\\\\\/dO5DbI01K0k\\\\\\\\\\\\\\\/fveXNosYkeGcTLWYbqEqaRvQqsqKc86lzu2GZAAwEee0CL7mhAqY6zbH7AJ1k5DyfzSzAPOEsTzaDln65YaWF3or7eqWh7nJ42E8A3fWrq443Rj5WFHCV+WEd5U5OkTy8qK8btAsBNuKpUr76XNmiyanmEFXBOUiXBT+V3bpXRMAxYcCkPeGDmlovhPztjkqJ8RIUZVA8qFr1kNN4GcNq5RiQQNQf6lPrfMtR8x2QjbPJfWR15xCAeRBISnrQHr74np9WIEq+wH8uYKPNO3wXP7jR4X5JUphjjE4JlN7KhfC9KG2G5xhkKmlDV4Jn3a+R8LUy+nUDOXdCFIO+zj3oanrnrzdBWmYjq9Ljvk4VKpB8zlLzwqydKamaI9RnOoRiYJqeg8nk08YttxHrG1jljq8qe\\\\\\\\\\\\\\\/tQ0KNcQoGxicLNlFIOqmiDbmzT9BPz5+hx62iH956HO+xzeMqolqkIjNkIl6H0RihbBNUv4DUqvLJl1i1Zn5D45QDWsYXt4KDjy5bo4QiWpUaUurQf89f4\\\\\\\\\\\\\\\/ZzzMIghrmr246GkyhYjJ738oS5VKUNKGEbLZt1DakezzwsGo4KitRIA3dwSgk8G+dOD1kEzCLP20Qnaqhleh6QLbFnBtviTg8S+sPG0SLyND1Jb6X9M+SFx1Th8aoyqxaT4ULAXm8hIyITYKK5aQBvjMh9At1RB2mran\\\\\\\\\\\\\\\/mGPQz8P5rj\\\\\\\\\\\\\\\/4vOV5aXyRkWQfHpRO3VgN4YvFAEi7+35K1dbneMvPLXMzwO3w29ypbLQWAHLTbBSB+IC+04GuhG56JvxeV5epmP\\\\\\\\\\\\\\\/9u8gmc1m0+yoc0DXcLkq83K5sevOspnHfKNb1gDp++OJx78+rpoUU0YPEQ+I\\\\\\\\\\\\\\\/2Rz03h0eKljPIXG3hZyMWrLwEHfdu2xJVQNvSgOu4lRof6SCPA+EMuQ\\\\\\\\\\\\\\\/9KQNLbiPyc7y2ac\\\\\\\\\\\\\\\/f83RqVxNHLa+Xq6VGoZGIShG0cnlW0\\\\\\\\\\\\\\\/xYQmL4NQc7YtkI4xby1+faBdIT5l7vD2SsKUlJT8Xhpw+zg149yw2CdrSouD3EPGsHGD8BE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00227fYArEMW72gTYQyOozirhQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00222cf9b8646bd649c7166b36990cee6cb826db18a6672a0074efc0032ea550ef33\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A80.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A80.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0130\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0130\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0130\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}