{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022aMU63PSk4iYcV3LtgLFUAhjpYZ39ZGtrpeOWL6aaZxcmDv7J83oimNgfV0R6PCQ2+4BBlAtK4cRIB8ZDn\\\\\\\\\\\\\\\/U\\\\\\\\\\\\\\\/KlccM+nj86+XUhnw+LfwWBMgoCGFodGeg5kqh9lmdOL8NQThmU660nqnWfxkwFo+O18UnNZi6jxse1mHgbsIWOvIP+7hM2+w46fYTM31bl+BB9CbbS01cm9+dlBdlaQUmtGlO+m95hs05ylsV06AOzSfjSvscFana2i1KprmWBDDKA8vHW2cxLy1cIqVl58ei2uLvq6qYss1u\\\\\\\\\\\\\\\/OajumjHNBNk0sfzgqnToVumbnDWE+doxryenyVd7sIyNU8\\\\\\\\\\\\\\\/Fbc20fqHLCrXhGeH5CbIVHa09Y0dQGNqEIfZSLSMwW1HnmvdR9lyRM9HNel8BJ8PUP3pvtL2Z\\\\\\\\\\\\\\\/DP+Ytgbl\\\\\\\\\\\\\\\/cX8KlWdAitXVE5jyEB\\\\\\\\\\\\\\\/w4rdW3i+T9ZZTbwHDRdTtzpiJKrSnQnw1rGEegM9oMhUDiovlXE9cpc2Cgb7BXemn+ui3HPQTz6wX8Pl4QobnuCGy93pV32U1nUfiPYaRbMyXx4h1Wlg1tleZvYNBPGuwjQQEC990m+rHCHM+jRxP27PTX+2baxxKjffYnTwwLuUL+ofZ2pBG5d5WMmcMoKDIhfT0DjKZAAcr\\\\\\\\\\\\\\\/3ib5U1oRtW7Mf4OM15o8UDY193jAKE6QbOhHBkQXNI2+UX0rS97reaUX3YHfz7EtdYG86cs4A6JBc1T7FBbyu\\\\\\\\\\\\\\\/jfl1QJCQnRJqpP2kehbjGdRfRR\\\\\\\\\\\\\\\/d\\\\\\\\\\\\\\\/DpvzRLmiJVTAtut0tz7sA\\\\\\\\\\\\\\\/AVW+40e3AyycV6Kt5Tr2TQ6+e32WbzdLfeHMhKSPXParfmy2P52JsQYoaiOwKMD5xrn\\\\\\\\\\\\\\\/BxsBeg1YXCozi6qU3NETt1dbnLoTkh1H5aYoQdbNpuVtfqofDLFEdvmOHaoqv72KPE+9evprtJjNUr0WvGoURbH8EESkUL13AMWiCV+T3gqpQTljVmh5Y9NPxGmsmsaGKDU0\\\\\\\\\\\\\\\/dWpDlmvIJn626JNEZw4SwqjnaYck9DrV7FV17RjprTdl+huy5wROiOc8Zd7DvOl6HvQg\\\\\\\\\\\\\\\/fviMAlyAuA3iWeNUVArjEv1KOXap8Q5ssfEWPkAWhVu9E84v92AXqDoiQ3Ir+NWpKOScq+ZngFCaHIpBS73F5L63BGxf\\\\\\\\\\\\\\\/lLPsmA7q969I9hA6gCjQZGDwGtA3Oy1rmzHJ0cMfrkD04CH62+VXbWkG2umIfrzndrtay\\\\\\\\\\\\\\\/OFmfwqkRKhUnMLrdDGBrc7zgX+FpRQ\\\\\\\\\\\\\\\/PJEzDm4XpMJDrKT8QLk9f97WAYM8eWk0MKzFxQqlLIiBL8+iWkWk4o2Ums4QzYbrLo5e2EGnbgiaSCGshN8vi1l7KEopYdkoJnVk5vbc4bZ8hOP6PpT477GW9bd49TUf6qk96vlqoBjJmVS5pwe2nBMUg9vJOTvYWnbJCIvHbemmeQmXvkWFcjwWe8qR4D5f7Gkzh36n3zxdy\\\\\\\\\\\\\\\/uu0fNAXJONWL6il5PGr2\\\\\\\\\\\\\\\/7OltLYnXh6+i2VkTn6ZVVR5gw4dFzqlttCLyVpaYhOGG\\\\\\\\\\\\\\\/dShf0iL\\\\\\\\\\\\\\\/t5P2c09TUK8aDbFbiFtFjKnhB2mQE4Zv9iL0XuCdVbIZ2zo\\\\\\\\\\\\\\\/waMuL\\\\\\\\\\\\\\\/LBlxdRKwANLGeyE6xM5UQxoIcGkljWiTjHGuM5moDoN6r7rbk9V71x58LJdU99XkMBE8Coh3DvNaWWfXQHwdi00aW89twWIRNHy4LyCQoyn0PoBIYlQfFfqZUG0Yt\\\\\\\\\\\\\\\/O80UhbItiNBXw2PUjZYg2Y1W0Ngp9rZFewYIU73wKviFKLs1YTKIVDcYel2M6DY31x7l9msIirE0xsrQWxEXOv\\\\\\\\\\\\\\\/kZFs\\\\\\\\\\\\\\\/ku5rtkS1uYgvFDEy+Ccy4HRdPs4e28Sht5s7eu7AidjKdJfiC1LZOv8rPasm\\\\\\\\\\\\\\\/LQrTW5Wf1r0FI5wKmBd+GVFIempsvDviCEpGtPlY2KYsNlUBYT4Jv\\\\\\\\\\\\\\\/5SkxVrJ8rD3Ev1UI1+ShV5T64Ty9sdtB585SXXlad4TmPGAlGeTtVSQUN0vHkvsswy2Vkk1D74p\\\\\\\\\\\\\\\/YMjNGSD6OrO1HrhqCwQ9d5Dj2Pf4RR8V1KIeOxXkYjhBecDrxvl6JTisYUW5Or5e9yd9kA3fcUGC82HdqzPpTyrq7qlrWuepGGCQXFCXSV23oTxi\\\\\\\\\\\\\\\/PKQsFQYovK+O7kfEPIehwcqCCw\\\\\\\\\\\\\\\/kEg23fWFTicYy8PUX5vx\\\\\\\\\\\\\\\/PKOvy4dxJfeWQFdJp4bldVnJsxl+ZmhCFaCh2kpaRkJROkTP1I6O+pKFkRCSDDe3K\\\\\\\\\\\\\\\/QgXw6fT5RvCkwKwNwk\\\\\\\\\\\\\\\/8z8W\\\\\\\\\\\\\\\/zG23\\\\\\\\\\\\\\\/nIKeu8ggTu4xbLTwvSTX3KDeJvjbQ2fOpx3OJJ933Nyxx4NcHYWl8IRyWNMnIEw\\\\\\\\\\\\\\\/eL0erqivAcyRiTo7R5kg2u9WKr0bKG68wjxdc+7sMTzq2wPZ97\\\\\\\\\\\\\\\/ZiJx5FhRJL\\\\\\\\\\\\\\\/rgZm8mpOVq\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/aSYao3snGbxpdqGicPfJxRn2\\\\\\\\\\\\\\\/lbmHHFffFe0a104lh9exH9VSy4AXVaGm0lZVXjkkDHHVSeZiEpTgG9AeDtv7obfJTEyrt3Maa0NdJ2PxKwfd2U9Za1jdgtdBqE8bMUHNIpOhuk4M3u4Z2vpa9HJECXjGIVWqFEeGc24VH+wo0cw7EHx8zW\\\\\\\\\\\\\\\/gNZhBPbfMy7E1hollAQcx+1nug6lsAKz1cE8Ji6I=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022pBVcrGlvuJQZ2609Vv++nw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022cf4fc945cb97963e3582c690e28935ff42f4031881cb4c91dc6962615b4e8e43\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A102.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A102.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0170\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0170\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0170\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}