{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022pzgruDVlzbHHT9WBZsSuWx5KKTSvGmSAXh3q+CZJegaJN1gG4KgpsFP4RmbLMsJuqGgXpvoL0UVmQufvmPyIh6h\\\\\\\\\\\\\\\/ElR9coU3ZRaO1BpL4WxZPQSf+OlD4ExRpOptiGTSexjQzLXgIcbw\\\\\\\\\\\\\\\/o4FoLDahJJQLs4\\\\\\\\\\\\\\\/jRmspV+SrrG6SdVY1xFK1wBaZbcXhjSOaW5ho+iclLagdBqDkltg0X86H7HSR1nqY\\\\\\\\\\\\\\\/ugdbs3M409b\\\\\\\\\\\\\\\/mucJ5PPf3HQSOnVvn\\\\\\\\\\\\\\\/Fwduj\\\\\\\\\\\\\\\/x16LR51Zdu43xF+yz65OA+ArwQhQPdHWfuRSUZcHKgX8CR0EntEwO4xvloBdk2q29XejsTnspuM\\\\\\\\\\\\\\\/29+b2mNHhEjZ1tzTBuBVi5tBDe1vCTvH6s05S1IdcNmocyaEplfdWmAcct1na84XSIfRgFBP+dKXq+JWDjtLoAH3LB3tB2yAhfdwgn6b1myxZJaxNg3+qtL41+eQ7mELjvyMGpripnrvKjhg3FgsZNXqaMWhxXZFCXvBgt5rQU3OySDK38zksOf8jZ7WqWeWn2zsES693rmE\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/B3+6SbZ97aSmv0cCpPVvi7aIRnx7+BBAvs3ql6kUrbgUh1NjqmUkqAmLfSfrtR14YAd0QpfKofH+nhAKAD4zFt8mrI0nheBsd3M5KmuWZuwfH68go++RbB\\\\\\\\\\\\\\\/9yF27aPB11xw2QOYMiI24EB8uiaH1hkL1LRQZpFILAZy11cdV9AZJtNij3H0xdtUGTe2yhDApx1XlrVyg\\\\\\\\\\\\\\\/f77lPz6jj6IeCSus2Ht0qb6Iw6A5FWxEWGccaNmL80iu7RWb7y6wqU\\\\\\\\\\\\\\\/0Sm3X8kEIBzABZ9H\\\\\\\\\\\\\\\/+6cAnhf7nVuGw48lGriSw0bcHCViO\\\\\\\\\\\\\\\/FjKjxpIu9PiCiGA9zUcSuNUhGvjPZQBhTtINsx7mGtXAmCHJX4RhEZNZ+3hCg7EZrYsjXYeQIYKvjX1UmTagLdx6S5bAZV7Sy9ghIBTA7YP70Ddy60IsDwhFkHI1ypZlZiBaY31ccmM48vPKCWFWuFagCliW1fXYtMkYypvoZ+CwzgWc2cQhvogINDDWSYiN0+uVtax2LcMCbcHIHnIlD7adwKiXlQuY29q5JUfUH6DBbiZExqqsYficWXm6+n2wVWzJIJm25u+y7qwrW2EkcAS+Yb+c3T1DXl3yK1\\\\\\\\\\\\\\\/xLEppELQ7CreDiIW\\\\\\\\\\\\\\\/J4YIkwlPf3BtGU\\\\\\\\\\\\\\\/hWHt\\\\\\\\\\\\\\\/WMg43AhJye6Nee4CvQJSEab57UGq9Hu8ClSUVe3b+jGznqsFm1tl2CcHh0W\\\\\\\\\\\\\\\/B9PrrLsr92SQTXFD79kMApy5vK0rTe0tHIxA6vBOZv0Dez\\\\\\\\\\\\\\\/Pn8badnJnF\\\\\\\\\\\\\\\/fAfgoRKjYwvzBkCXc5TOKFMlrEB+\\\\\\\\\\\\\\\/6Y2cxtb5qxk0\\\\\\\\\\\\\\\/6iF4KxaBn0VGvH8neFrB8\\\\\\\\\\\\\\\/e9adK8IhQgag4kGYsruMsWkQ\\\\\\\\\\\\\\\/7v0H3J78iLYX7aUcJKUkM83QeVIbDSjiwcM9ymTRqf9OSSLTLqAoVuTqAMLFImpEBl77fv4C1kLE06rkjXQPt+UKzdr4dM8mJ5MzvI+S2FBeuxuP6OIFc26DLmlxeZ9Ev1u0LPd92k\\\\\\\\\\\\\\\/reTzxLnQBb8VDTx9EmvlNYBfdDrQqehBTwgqe+JTa+mwkAHt2KjZJyUMxJCmT5lPY4uQkfkYIPRJ5k15l1YcarfCFQa0smtALpdpjwAFLNtk2Qhm\\\\\\\\\\\\\\\/ohL20jMI\\\\\\\\\\\\\\\/NiTx7eeqglgDhdyLrQOurn6xNNFrXoC3BdaxP89zZeUijon0iD7AzaAfvxRSfJ\\\\\\\\\\\\\\\/kNJz2d\\\\\\\\\\\\\\\/0bBzcIoPouF9Ho6RfL5lTovoim9t+XmtoyYLfcd01AJx0C8M+O2IJxvxcP8TDWZGsIP4o1j0YhudTe9Y0Uv1eUd\\\\\\\\\\\\\\\/TG\\\\\\\\\\\\\\\/1WsjyT76jF7uu0xdiI3qqfsV+jqovkkl1X7ASx2BvUfkd\\\\\\\\\\\\\\\/WCPs4N4LxWScOnRvq4+YuB9eg6eRON8VB6sRnVY18ovQNOPbwm5ruE5Y1IkKr9lpEbBsMjXxAAUiiwihDMd23xr9WNv4y4sXoxBHABog7\\\\\\\\\\\\\\\/eTqe9mFQRK2Q6+EneI+AJgUet5QgRMbyZ6oGubSmjZsRSazbopDsQyIB3ZJr2RYfRbXNNFc4j622rvfV8PDaE8gqvJAbE59ppVOfNizrQKRVl72iSMq1skaoLWJEWP1+oob8a0MY7u4uIgLZ3KnyWmqqzkFqc+MZ+n423djoZ4o2O1evAW\\\\\\\\\\\\\\\/wIjJ0PHdc0x39nra4b3kT+ViFuEepVc4DEyVlSFS92yhPgBUsXCD6D7u9OUPKlKm6a\\\\\\\\\\\\\\\/kwMJjB2xXDLNul44jX0\\\\\\\\\\\\\\\/tClKwEGt3nbXfOfuAf5m51zXZ3w4iBggAdAQCUxoTCIaGnovJyaCokP7\\\\\\\\\\\\\\\/oIBhvdiMdCmL4noSR1xgsnW+5P81y0jpSzgi10j5ZZmeYDoC0s95ZmwzvADbVKGyuJEigyOfnSspkdvApZuDTodvkdVtf4BAHOI9kTv6hJ0Qe9C4DMoMJCYYnCeDkRH+sut6WmhHQ\\\\\\\\\\\\\\\/WYGV82XO5qLcvMiLSS9wNWKQccH9lH+Cm83YRwfYwJEKtnaw3eUogpaZQIonz106Aq86vWULJdXQlDt76kuwjitP\\\\\\\\\\\\\\\/4AqbYtyiOStYuEipHteaQsmHudYjQSnkXXLzBAhjvLMxXWi1dJqj7RALh1rit1NlwrLoluG+Gx6RUrxn6C+hEw0hxOF1bi+v0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022S03DfBoHK7TXjwVcxiUHXQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002213c90dc65d25587dfd51439839a1ae2fa75e1ddd6f1151d00c56f009a7d44c3a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A398.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A398.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0664\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0664\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0664\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}