{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ldQ3yEb5R9gMiXtxQc6DOG74Lx0soOLsijItL7bB68GTFo08h0euNeTHSRjsns\\\\\\\\\\\\\\\/C2R4863tsSZhEyaPrvV1t03JtNvirnggDOl+0g442f7MR5MDoklbZpBu\\\\\\\\\\\\\\\/kNj4AxqZDaH+swIQ65s7e4C9fRkTQq2RTLmJKj5vP6vStl+WiDg8b212M3sNSxl9S4usMyQ55QuKDwu6s1iFafQ2APeLGc\\\\\\\\\\\\\\\/xBfqRVIQvu3j7CIm055eFNYzGYgGjfhDEnNUEA5fr4dLAUmtwZt0pihXoyk6cQp51pP4M0EIEsRjyFRMOpUwj6zUl3g4rWfAy1c4XUmygXaIiZi7k\\\\\\\\\\\\\\\/s7p+WiaKJdRe7PrS9THUBDE5iy\\\\\\\\\\\\\\\/JU3PwAx7DdG60nvci\\\\\\\\\\\\\\\/ZYquwGGlOT38l4IEHxV3we+Taxim8RBsNUfjdPYYRtuePS2CJLeU+fTwbPYM3rFE2lHlvyvBj4u1pma4vcp6PtkAw3nZS8BwL1ukDcZhicFRpyQlySiQRbtpQX\\\\\\\\\\\\\\\/ld7nmOr0jEW5gtUdWd2Q1qEQjKs8P0JJvoHvSNZszY9Fwss\\\\\\\\\\\\\\\/i\\\\\\\\\\\\\\\/Hk2myTN2jW\\\\\\\\\\\\\\\/zbwfTL58lPn8w3vS249bBXcJTmnhZS1mRjMGApJdhYwPoHZl94JMlBpi0WwZfVqKpFsS0vaigxf38qAf4cowV+qNYyhtuV51rvJsLqkvZhowPygyqWJ54l2kyNWcmyg42Q4oVgR33iwNwUUnmAbRGhcXP3y5bcZARs8jEK9f\\\\\\\\\\\\\\\/Mzn1DFfljUwWbJiz45nVCuKZlLSOcqxofX9oHX8chKNUY8S8J8Dt2VmiY9o93kNgAAkwGQGbPrVBftA1EWcMZimAASVAqFr8jaWg2GR1fbrtaCi2xXz6blceDXKD4SQ+IcwIOdSxB9vPVn9gsC\\\\\\\\\\\\\\\/hydeVg0aT66omFmJd5Db4zxnjU\\\\\\\\\\\\\\\/h08apeuhjnk5NRDLq\\\\\\\\\\\\\\\/0Xz8INYRKiGyoG1hkoWk4WnNGvOW9b9Rv6JNEOvboFmyZe06T6Gt5SBQpd+81I+67ADs6T9r6xEgJPkkC7kckwnMWyKy7nGM3e3lLzgCSDLlbnTUVNzU+oIF4V2tJL1BUYk7Fn3xTHSUV2pFnHaXoLb6BinO41rR\\\\\\\\\\\\\\\/ekf3mmWC\\\\\\\\\\\\\\\/N4zrhm4R76VhPU8il7sGfyYmAXQJ38X+zHZIAnfPR3QMVf2we+mdQzHurEjzPwrV1TCsvK7vZaC3YV4Go1POxQJCt9m5qXZmKCE7CXLMmqVMDOLGR6sOGj0gU4MLDZ+DU0xxX56Nspfb2KhzTn+MvwqPUSCM\\\\\\\\\\\\\\\/TnBpGEvedm8gIsGYMqiI8yHgbynqVjO2NUHkX32aob+wKDGLJKHDp7kjYzmsVsmpZbFXzk7z3pwCoZEEEXaciFmC8gtxvzUOLQ4deh60t2pwRauYEnB3IyhxQbZpS7ayzuvJwWB7fSv2tngdGqq+G3CgHicpPLZvlk0gJV17qIH3FlXSj1LeT7Vgkld3V19uhg7SJCJPu\\\\\\\\\\\\\\\/rt6UIF9Ew3bNrumXF4Ma05P+z\\\\\\\\\\\\\\\/fveKjuwwXwWsOKHcNBOHQhkwH7f3go8uVk+07TiHeda7ixig9echIiIK\\\\\\\\\\\\\\\/Vca7\\\\\\\\\\\\\\\/HD+Xl7McPs2TEJd3hgM0deT3Cb1bGhlcCwsc7\\\\\\\\\\\\\\\/cLfQPYD6hpccoQNR54HArG6qp0dmMyhGir9M8X4gKzlafI2yD3uYmNqxJG01z77Qo0NirJEOptVaqNiFVST1uSefhjhGebngBvVGbg9ZdZC+KoYLoIOPEHMeX1nnlel66x9b2+NUvRsusfHMznl0EqqWWKl7nrnmAlDMAmGWOmPNm+ODt6fZD3\\\\\\\\\\\\\\\/urO4rSjdws0SVnyhbURdd5mskd8qmNgPmb9HA+9XdGCGHOkyIG5pBpmLk4Blu4tri4JvLRfngAyv+0WueuiSGWp1WQ2Pj8OAPoKzmF\\\\\\\\\\\\\\\/sCy6ZTXtW4DgXjCU+spRSVmk8uw260feZhFge+5ExppZTPr1m1cZBDivnF\\\\\\\\\\\\\\\/mmnHaWLnXeyY8tN\\\\\\\\\\\\\\\/CePeNNkmOUQ3FNMEqF+h5aSLadPW8SFstpwmDzNiWfbHPMtAPbHV83bveQACH\\\\\\\\\\\\\\\/Zb4jCEc4lzRRYGjQc8Vs9i6qCrMDM\\\\\\\\\\\\\\\/PzbtUY0szEDhKeISKFzSujeSzuFOKGIwF\\\\\\\\\\\\\\\/WFQmJo3Wc4aCWCEab59opJ3KOME1dm0919KlHw2fK2wMva9zmag1eZd4s\\\\\\\\\\\\\\\/uyFwgx5c\\\\\\\\\\\\\\\/AJ4BU2OrGqBcxcM7vFFn1LI+tV4vzU52qMS0chYE2SZDK\\\\\\\\\\\\\\\/x7\\\\\\\\\\\\\\\/4bPCV7xJU9thUlblVFd041FhBgoEuDQVfv8r7a3py+set1dcL6rGn0HCS6N52MXNUMU35Qwg4gW+idoQyKBsaAtCj0a+d7nTUJVrHAZ4\\\\\\\\\\\\\\\/08CVnCBEWe+BDKXICdSurHu\\\\\\\\\\\\\\\/pDuKTy5\\\\\\\\\\\\\\\/6hWgDUI5UggDaiv4AAjvTdWygZTL5cHSnsKaVHTZcCyYqrWAJ2\\\\\\\\\\\\\\\/pQew8+kbxnCIHibKonb0phuOmZtb5QudKdK6oj93kmKgzyOUddIt\\\\\\\\\\\\\\\/Px4o6PRfVFFVKT\\\\\\\\\\\\\\\/sVMKvfL+C3tVAmzMEKwpThQ09U1JiewUboo\\\\\\\\\\\\\\\/iHfpCBuDO1f4WW5MrzTViCGRb12Uafe6kihVAwL46wnz6YzOnWGCUs0bj8UZHYGfc2Nl1j+\\\\\\\\\\\\\\\/iVCH+eZKGHA8QNTNUDQJM4Ibx7AHXyLEqVv+ECytsIdXSz8LdBNaHojCMGULBE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022FgvpId6Pt6V1JvDHgujG1Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002289ddd39862f9fe571117def7e4f4c257986131a37b7a5fa5e61caa5a0f0dae68\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A454.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A454.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0758\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0758\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0758\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}