{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022D2qoAiW6\\\\\\\\\\\\\\\/DdYWPjmFxDJJ89zx9VUOo7usFtih4l7KlaLKFyPNGelEAlc8NkyrmgB4SUM2S0FUaUUPRyZWv089rUrBK6T1eY6HD2WfWyZRH1P+ADHNu5QQW7eOvvt22o2r7QraMWVz+\\\\\\\\\\\\\\\/ySXigKqvf6FvGcXNosyKZZ7yxiB7OmSZNz2dPW2Bn6+qI5nFqsxMQZ+hCb3\\\\\\\\\\\\\\\/0vnLV06\\\\\\\\\\\\\\\/kaJV6XhoGeTDzWVGOtooFvXdJ5\\\\\\\\\\\\\\\/hesptGtssKVSRPOMfFgClAEYh+guXbjEy3L7tBx\\\\\\\\\\\\\\\/lBZTTpuAItuLKznEuIJuKeAZfbMGBJbg5nDA\\\\\\\\\\\\\\\/Bm9iPLuHuGY50lblkEjtwit8s6fXkbwd6T0TGDtm30vL6t4prMtrwyby3w2oPOkO+X6\\\\\\\\\\\\\\\/THtaVkRwkhnkjHAXy4Y1yAydTGhFhDN7E9J+vgHWX\\\\\\\\\\\\\\\/eqYYcJ8BY1VIqUhb5L2E5nFRp3qdD3GnYcK1mH8gGxEWtCQY6gvqvJUU7QLPxUn\\\\\\\\\\\\\\\/l9r3Yj+WolUQiDyEKk8qDimKCWKdp6xYgI6+TqzUsN3KnefOUNdXcSIhkPtzjcmG9P25SdvJCekFti+hV0QhR9KRaIDq+jELyHu3mPrE1udfuNmJzVnG65RCB0V2ru1bpEwUSNzlxQhol9Kt9epTiF2auGd5Ut7FtrtzMQ8bPHsHrHQMNC4X\\\\\\\\\\\\\\\/cbCJppy+lZzB1OxNH2dmHR6pOEK4GqCAufAlaK7c6xIuB4Ti4g+Bf\\\\\\\\\\\\\\\/GJcWYKARJAWCGrPxNqg7KDln0Ilq7P\\\\\\\\\\\\\\\/h50fKc0GS70dpkNaA\\\\\\\\\\\\\\\/6xzBGmgHKUwju4onUuhLlonfExje77VOHGqAHWVc+LiGW01qJTxDApxew3vosb6bH2q135\\\\\\\\\\\\\\\/b0GIZ7jOQDK+DdQk9Bo3Ereb03xPAxBa5cghSK7YSNhXJhyqiQVo\\\\\\\\\\\\\\\/+PoFYlfxGPNOB2dBB8sViELwMSrP+6jw2uX2yw4eoBigSehpWDv\\\\\\\\\\\\\\\/ABcZ4IEOSgVKz1B8xgrF24hPp36X33fBCpKlS7kl2JE4jMjghzJvFlTNMdSm8IV0VsLcToMeE7jPo9X\\\\\\\\\\\\\\\/VnbudHUN\\\\\\\\\\\\\\\/8eCmxSwWAL2qPKBOevm\\\\\\\\\\\\\\\/BovmKyVMMpRv08kPQyQnZ0vjTeqm5lBwW7\\\\\\\\\\\\\\\/exq5o8c4UCJ\\\\\\\\\\\\\\\/4ePQ1nGzlAxAD615GE45YqFoabNQrGPkO6+PnaPm0+A2FNFHh\\\\\\\\\\\\\\\/88kyV81aDP8TIFiwnm\\\\\\\\\\\\\\\/7dbC2vAQC3bCJutP6IHZHp8MDQEdk80\\\\\\\\\\\\\\\/2o126x4qdWFZi1rmoskYG1YYx5AceCCm+fCs2oNIcLiZFUhqWGmn\\\\\\\\\\\\\\\/Xgir2eou+aCrPeP5ijFrCNCbQsdCGeigBHLh5yxwY6jX8eV5rhgpCQ+G5h7F8j1z9Q\\\\\\\\\\\\\\\/qJ69POe05tvbAtUSioLGgovdqTkmo2JvWR76VFGxvGQCTUdMq2UitbfCr+DriqGg8rfYc98umVsd\\\\\\\\\\\\\\\/AeW4st9o4rtH\\\\\\\\\\\\\\\/hr5oAL6QubAge0EbyMhGvTYmPgOo2Y\\\\\\\\\\\\\\\/Cfzd7sNI1m7zveqzMUKjJ750uZQ+DeDdCZOFNcwKei138FaSdJlhz9d9sqxOSUAN6ONeMVddLgavzOeRWSXC8700FhAqN8iNE5ADAb8G2pHO3eu+sICI\\\\\\\\\\\\\\\/d6PEJYd3edOYkALlstXppK3VfS4ZFHdmjIkwx6SiA9fp6E9R4ZCkCtVNSe1eZzv4NwVibUuG+4rk3tKKuA6FtT+j8iiCilnoLIMTvxab3Gnrdc0HvFgpUW74goL8QLqIv3eAMEMyRrv+bHS+eIGFBumM22TIDWS1nM6pBXLZLr0Ni0x4cI3gvEjP6G0eUonPkJrwXj\\\\\\\\\\\\\\\/K3Nnsv+V1+oPhldGFK\\\\\\\\\\\\\\\/LnESsavFF\\\\\\\\\\\\\\\/Sef4qkb3I2vvbDEclGRn2xWaLT\\\\\\\\\\\\\\\/sGFLPGY8snW8B6O44tI+d+mIkyjteI6xc4pyC4RZFCtaS4ixvKFZy0eazk0YbUQ2Qm4khsh9rJ1xmTPn5LUS3b11LTRWDGmMPNVxZD937D1K18dDE3UMfdwNPKMA4k+Qk8\\\\\\\\\\\\\\\/DnopXx2wXPfObkxJ0s8n+6nwA6QMduqZftbcJjP4Cro5EXw1lLt9vegMsKEfjJhCZaZdwRFb75R\\\\\\\\\\\\\\\/Go0JvITrmQKw5GiMeRmHodOYIPdaqt2hqn2SVGZWcdVMp0\\\\\\\\\\\\\\\/19tz\\\\\\\\\\\\\\\/YccBnB3tmA9ySjg6FLUDA8\\\\\\\\\\\\\\\/ENgELsH9RRNBr96QWAVB2xSe0JIaHjCRD\\\\\\\\\\\\\\\/a1fquZNjvHG+4ZzK2xxXcyH9z2T0eQL0arN2Vy82zoXCqXnQzsuK\\\\\\\\\\\\\\\/zPuuctBzXq03VTXr4moaZeIC0JNWDWZQ9BkYD2PHkHYvqApOW5XgArx1scry6L2c7oxx0Ge8cVmY9pyvPci+3IsZSWJw+nC1+kxhrr6bS\\\\\\\\\\\\\\\/cTY69TaHp3WAJLagO1ppvhN5tSbWW5gmgok7lM2BKda4uMcSRRydi81\\\\\\\\\\\\\\\/dAxDrBoRe0t6bFU3ekHmNN3mJ2BdzcrLn3\\\\\\\\\\\\\\\/e6oQvyWazKhQ+Q0k3DwxOJ4OZjX37KS+o9HchGbwSLqNfvNdXjgP4IJeFBYGoXuhBbAYXVsxv0UD4+icai9mThjzfDI2KXZl70WHzHYve+XG2uORsPdXcyE1RAt5um18UmMwo7pxRTFdmZA0asV3RnbhKyv7hSODmn5YAd0hIKH1vzuI3DJQH6VRqRhL1J2BaQwU8WtotbtnVJdynSPoxNzNsaUFsM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022OanDhEffCN7I6e8Fi054rw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022e7bb4bf358f75546ed1b42f2f760615c9bf010bb2fe78cdc862d6238b9e06696\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A382.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A382.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0638\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0638\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0638\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}