{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022FdbSGBcu0LehotdWbp+QWfJLY+0KiIxPCXL4cOS9FmVthGYInbxi+ALJl\\\\\\\\\\\\\\\/JIPNUk+J3BZ94BtOsqwqSCKE6kglCeoamjWdQ4ihcWuMhRXO40C0lzPrKfYyAjrqwACFYukPzbtDGAMR0kjdRgIYl\\\\\\\\\\\\\\\/lO9umVQgGfAl72nfuoa2SDh34spmjarFjNvfh9PLW7dMfE9XLmQIVoaMUHsM\\\\\\\\\\\\\\\/dnE+NgtrXcVk69436prk5q8F0+zl\\\\\\\\\\\\\\\/4s9ybQTYKXaD4AXWrNFu+sCJK4heudPSs4ks72R5UIRAidykUfnBbRbV7RKpEc0mh4b3n+ydT3SmX68fdhviO+XEqH6IINjjwwkIpcWSGDSZM+kScEEx60QRJogkIVWq6DXaC4P2Sx7js2w+F3d1W459N3RJOWs50PTXwTFeojrIUZiBDv8ylFEeE8u1O\\\\\\\\\\\\\\\/qU8+9llLPoR0C4M+KUZFhJQ59JyAIGtcMQ9mcUMwrC3pB5xUQvE+BF\\\\\\\\\\\\\\\/+uR41CdRe26fWnN0gVBy13f8ndzxqzL3iOAGKQaVTvVRkE6jHC3eE+qS8RogaNnHgyJl61KEJthWSkRh\\\\\\\\\\\\\\\/0teb1xkVK+SymEkB0tDRT+\\\\\\\\\\\\\\\/QkTUA+8nbbB4zZsqroG5jJjwblmO1KMJDxazfcOhyy1fk98g8wKbt0fGmBY3wvFFaQD7uP96AyODmbWwargLIyoxS3xQPOU+5BP2ZsjNCQTwU9sBqOB21m1O3zyBldw+KVSFnnGtpkFOlEXWqiNMaGRnRz0AycsiKOJXrlvyasS9KGbifHL+TFvbcILBA9M6SRpZNSpI\\\\\\\\\\\\\\\/G1Bn5bziMG\\\\\\\\\\\\\\\/yCy3OHZL4Nl4WHZcYQ+2ZuXz4E+vrMM3qYoVFb6Y8PFP9mUQXbPX9UZlybSL3BYJxUX\\\\\\\\\\\\\\\/0n7rzTswBuhwEZxiiG8S32aC4nwMtMkaCtWpqoUDsDnavkNTcMVD7HxSEONWEE58OgLsLKmJ5b3HG\\\\\\\\\\\\\\\/tnVhzQpNZbaB7VqpAs681in1JOtd+VtnOSkukwK3jYm\\\\\\\\\\\\\\\/wmASFsGmdW1OZCace4qzcB+kylNB2KBHT4XXYO9YQwlkKDhU896A6t6qZF9zBTKNg+OHTs+LP1miYW0Qg4rXvVqPQfdp\\\\\\\\\\\\\\\/PKp\\\\\\\\\\\\\\\/g6FYCnoaEGyKrqFykxv6Z\\\\\\\\\\\\\\\/qD3o+k+HRk\\\\\\\\\\\\\\\/7WC1LXAUO5DafOHNJtz8pSjRSg3u7P21Jl\\\\\\\\\\\\\\\/cnj+EYMaOwaxnodBmNp7+o57Q7Q2TcXMB7PCjAJpFaWZi6dKRZH88NsKnjjP8PgtcNcnY1I+kLMgRRCy6DOEQkNg6lxlqHDebXmIavU2MEbn+dwpj9KigfS18Itvsxu06tEDkM7IszZQ6yv\\\\\\\\\\\\\\\/ER5GhCFunU5p1LSb51OlDpKPO4TeNtS\\\\\\\\\\\\\\\/+piD6SSxMsLZ8GkIWrlVRuTXp2bN\\\\\\\\\\\\\\\/6QhCgXK6mEDQbEy+kaDrDLfhxgyfmW+vFzwbviMxSnesGnmp1kLyUt\\\\\\\\\\\\\\\/ztpwXPBmplUvgYtMiWsVVgoy\\\\\\\\\\\\\\\/U9\\\\\\\\\\\\\\\/AfRd9dUlHgiEt0TEgvqWriVxz4JM4uoQzGaUNAHFehXO\\\\\\\\\\\\\\\/Ihe8+avDv\\\\\\\\\\\\\\\/eNZz3EIuuEsEuF42pFBm982rueyHxyi9jAUJMFGBpiZhyIxuhABrxrGSujt8On4F2rTEmU9MqO+B4fl7QDY1a9Xhu7YQoUX6tMDk0ulMo2klsL1A0LM4tsE\\\\\\\\\\\\\\\/nQz61YSb\\\\\\\\\\\\\\\/sGedI7Mg8XFNv0o0h1hViP1vhG+JvpH\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/YsUJ7chHAwrTXsFPxaMmXfe652VMXxAstssIkwxU1PBQPk2Bd7lB2X2IlRTz5TKHvxmVb2qhKUbmw333eUiQRF8SXaQVupWP5AQI\\\\\\\\\\\\\\\/kjVSua6dG+zmsdNUc++m1f6F4QUGoAbeB1j30xfc7Zeab29De3eFovTPiKjk6SEWrNPDF+czbFQLHK+CoEy\\\\\\\\\\\\\\\/+GBNsnb75AQJ0udMdaQwVOevJWdEtykiSo52R+YzcMv77MRUcTl6BJ8Nr0uKyHb3ddsGfnTgckCXCaMUixya3iIxGrnctDIBUfHFYTkTXUnvoboi5zWumsquECFmhqQy86h\\\\\\\\\\\\\\\/0byhy6mEp3S3csK1jO32fyh633BflkUzSoM9McASSZqhR0FslbTvE+g4DUofyYRcQ4pUyK+YN1yBnsdODN6b8QmLXX1RPTeqVBx492D3O8nhB8w6XlwthzJBjwjTj66KHiPrzxg0Cafs7cP0ISAl8DBqbejQMK3xzHrI3XoqT7iLVMZbN+PjxVK\\\\\\\\\\\\\\\/b3Y82XJAYQPQcXQ8PFNR263LTitM6Lgo2HLzXsjdeHFltfaskiFVKShBTDwVFX658UcGA9Jhi24fC7i1UoRF0HCnL88+HMaaa+xW0eJ8AXTG9NF9bFi+QWDIYGAzQEg4CYoRb8McPWtpMUSBH2SY3APvWWEtA2qAPjA2lSGi9govxbrbHVZqExMhwZ5Czg7fxBxSNfJm2SOESNG7OidT6y00xrzhEZ74hXyt1xqrqr25Zp+NG1youcR1oYMpKoEVKticZJT2hRBy5Ki832OMFNzIB7n1o3kVnpTaYZpC5s2+ch\\\\\\\\\\\\\\\/KE46d96ZQkam657K7cGq0JtDYt7IsaHQBpmHKh0kU9xZQNTtDDBj1UsnY4ClMi5YJFdW2jNdIClNRYef+dJ+raYo29Ho\\\\\\\\\\\\\\\/wtHql5bBvStKVV0x1z2+UnjKMdLGIjN8qJ\\\\\\\\\\\\\\\/WRy6SJXQ\\\\\\\\\\\\\\\/gTQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022LOQ\\\\\\\\\\\\\\\/IpTqa4VyQ0QukhJZQQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228755dc837e7ea25e06fbc3acd2d954733942b77d9f214a0825936df7dcd7ead6\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A499.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A499.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0835\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0835\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0835\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}