{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ACyWUU+QNnjXAbbxASkx3\\\\\\\\\\\\\\\/sQmnzjCfb1UvorQt9OzRSkYlyfyp5Z3oRR87yq7l4TYXV9vPoehzVnO2vNzOFXI7Y51qpF7hH0P+AdDJVcn7MKAuATC1j8k1x90pnyzjzRhL5cGVNRzo2uUrm5\\\\\\\\\\\\\\\/oyAD7e\\\\\\\\\\\\\\\/SBj7fSMvWFGBVFUKwJXyQDthumZ+IcSFEro61bqwxyRs+5d+98QCcUkpPk\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/c20wZlNiSaxFyE6LPXwT2vEZfMv1VSVrukPWd4u33ziC31EWJMh6qa9QemDu8ltC0ClJcrjlbUhuwZ8\\\\\\\\\\\\\\\/dVkqhGnqIOLWPVdWULFAekHVN3j9f9KTbMGrPNQ6hSodqN\\\\\\\\\\\\\\\/0Dl4otpK7JApKZG\\\\\\\\\\\\\\\/B7LeAwy\\\\\\\\\\\\\\\/1mtQYDdH7kUVo1z3aDQA6Q4WfOwc6rZLJTtuaT31WwFrXeq5v5qqh8kU8M2obRaZHg8NtehIx7FhNeGoFQE4Rw98dbpm6ovVbQ9ZmiTuKM2NwTJWJKgdXZfl0d4gXpYWDKpePdmy+7e1Ox8MFqoXStl\\\\\\\\\\\\\\\/AaW9YSBAK8eyeJajZ6kNozPA1DGdWPma8P8U1Wja5505Ghpp7QMrO01lAo+59UCIt2ozzTH3qE5aU41tw1\\\\\\\\\\\\\\\/hmCayiJehuK+u6DeRLn74\\\\\\\\\\\\\\\/vykxWbfAYYgD3PV8jcWXHemmCYx4oMJeTUmGcmUrFDeIdZj0FiFaGWRXuw06EkKsVQdsfSOrJ7l\\\\\\\\\\\\\\\/8OLIVIjgVkAyGIc84NBIq4KDZwmL4gfDZCxjPVwFFaTvfnHK305IjCadnORas1GrRY5c2IJMRYamWcrSQt5FoXalyU7EpLk0YteMiia9Q+cEANVx+pBHzD05+vlz1M0UvdEsLyqezu5b4TuW2KuShAQy5vs4yrelmkRjA\\\\\\\\\\\\\\\/cnnTyUcuM5zbIbqOvPjYZ+RsNic6YWqkBfLpxUEm6jvgDM8DFyTN0UJdOWrTYLU8yPBaiJaa4Ak6bD6Z8LFl3BdSpk9FuxPVSkvVy9aXGfElGSe\\\\\\\\\\\\\\\/OIj2n9TB9RfKVVhWWh51mJOU+xja6Ki7Rs9y\\\\\\\\\\\\\\\/cHhX9GL5cisfGrDFRhoHk\\\\\\\\\\\\\\\/yaIHg64PUJML6Zkih+T\\\\\\\\\\\\\\\/qRF0vNHKa+OLa44DahDTH3SftD4R3hakqV4pCWy8rZOHDQSWZbSmN0Mq9gZhjtjv8qpw4wG7zk8bwKCLmMKUE7S3q1HPQbHAD5Pg8GM18IKcamhSTBiKvVOf+IAlmL8YORlqRLLZBR2s7r9xiVYCukLn5Cwpv5Ay3EJxSBdCnijhOLiCNtEpPhkHsbXmwkgBwCEhQBvtquP7792Tz9d7nITRCwUWGLcN3trdOQnEOaxbssPlwBhKR9KzpmJjjh\\\\\\\\\\\\\\\/LQLhqlk75qQH0B4Wg1JWDulJRMR2PZLvLEyj7pY3KRMCLIHpwaAgtNG\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/BBdjlDcxc5HPnBCPZI7OxLk4RYVmijJgSWjlZCQz7lJkP57mTib+b90syOOeBO8eiZ38xG\\\\\\\\\\\\\\\/6ZT9ngh7y7d0oHTovynDdiouMQsI8C36KvLBuPdaQHgZxQ0bJPqKVqsWsSw3ncSjBuewW+VCPYp1byCinjGPBAMbdzAHhmz+lBsClB+ekNqP9UQvwHu\\\\\\\\\\\\\\\/w10hiOeJ97hSbofa42YUedGa2v8yVc40p1glxYyqyBIMFiTbDwFK3J8GpQkevks25hfYiUMy0UHiRD7nlZtZgwZAuyNARDWBFYdTdYuV\\\\\\\\\\\\\\\/DL\\\\\\\\\\\\\\\/G4oa9QThnQ214bmYyDG7nm9OUWI8iPK2NTLwFZJq9xIRVRVFGI9RdYJbKHaFVk2Hj6DdEnwKc2zr+Rllo91OUl\\\\\\\\\\\\\\\/xzKIXLrGFL\\\\\\\\\\\\\\\/WpkoMdB7+aOf4qH2gma4H38F8zV0MuDqT1er1nINmtv\\\\\\\\\\\\\\\/nW7WHZZmFh1frFoONtXU6lTwwyWIfxwx0zMlYaIG92iB5slAqncktiaqjIcsCkINlYHS8Bc1pMDVc\\\\\\\\\\\\\\\/eW6fIQuWYADHXMONO2HEK7KvOpVR08RsSAANwa0EhAt4UgIOu9gzDIqX069cJ0Uze171LRh5Pg4vwafd6+sdg8sptMFR5U1jv2zidt0Mh\\\\\\\\\\\\\\\/IqfAvNIDcQSJwxDw8fzOJILj1KXEk\\\\\\\\\\\\\\\/6ASELLh9Yq19s5G9Ab6A\\\\\\\\\\\\\\\/3Xr9+RyVLlkKRldrD\\\\\\\\\\\\\\\/6mUnliqAtlDpBv8B9PTPtEis5Kh4+fyFY+E9ibEhwW1E8dyixgSQZktzIwjv6kaknNjU0saim+RO1Ndn3\\\\\\\\\\\\\\\/R9qYARBil1YAWXSeni4s5Jt8uDsyyRSa+3M6nnyLLoudhb4wCIAq194kUsBFMP3qoTA4HqANtJVvZs0qu7qVSgyG1eAmsQg+zzKF9VlpljvtDT6Tv3Al7jhogU+4pdq3nN4Jhq\\\\\\\\\\\\\\\/cIjSRTZB612re4Jvu40Cf6oJMxe\\\\\\\\\\\\\\\/2rxFu\\\\\\\\\\\\\\\/IYkr\\\\\\\\\\\\\\\/YS7HU+dQ0mkklmu4KaQ2joVhlxuN\\\\\\\\\\\\\\\/sCzn4Bs6qWrUiMm5FzwcQjyN8WXSgApld+BxYBgVahhYKXEJvxpjWER43R9l+JiAXb3qJsbB\\\\\\\\\\\\\\\/OtiG0K8iC480TagY6sfdqg+zaqwhdGmlPPLvtsbeMkRZJRBeNI8IC55dl+HTMTKx2gnYTZyY5nyyt1SXUZjVnbEQaZLTROPIP7f2dY78jW6k7yOQ01lLRZiZRHiqSLnNuzDWF8sUCmzJk6HBxlJO2D+OSXUo9yAIlwuYRfCa+0zS6PDZHSDXJmIBS6Fj4s=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022DIJ5mDdwLJpnfcGhy6bc\\\\\\\\\\\\\\\/g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002250d43cf11bd9802e7b8c32d6b6ccb386b6471dfbe7ad497d03e26ce2f037e209\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A272.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A272.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0448\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0448\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0448\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}