{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022uPH1mxE+H6EynpmQ3OHeCm\\\\\\\\\\\\\\\/gXDAuWqfnjaIPmTxJ16mZLOaXxUO0q3vYuGgoQSFRYAUbWU6+qtAVM74w7njvIMte9HdsU4ktmOuIBraolA3rxtwc2ZOXgt+x3jBd4kl20csYKBEdrinVd5glqNdXW+myBYSTpW2cZMiZMTMRN9fy6HgqhdDB0e32P0s7KaWOXvSwYzg9Eb5NE3ac+rSkUAdkeHj6bwcnVenjAxUTcjCg5XazEPPNbAKrjFF6ZsPAu44xfH92KBR1h2CmAbCnNStTvtjCpF\\\\\\\\\\\\\\\/nTCr9mh6iMA8BIVGul6dUVqmPw\\\\\\\\\\\\\\\/cEcjA+Ty9q4kGLW+fKmoIMm6ogmtIQJ8O\\\\\\\\\\\\\\\/5h68iDZbubvkyzMsov7CU+AIG8OLdP02Wy942bJbNlFjts2S+\\\\\\\\\\\\\\\/i06NpWVhrcpADv61Txao63VM8TYzO8iX3RAbMCvz0+Z3cgcKraDqbtxaRips8aKE3rYi7R+FK+GwsKBTaXSfJv6WBUmZgVyovw7voHXwlSxJaV9M+4abeCy3cWXwoMs2pfapMUjnU6Kd0QVHhoSxWTmes\\\\\\\\\\\\\\\/bhRWxYrU4fnFCol40a8KGDyZXBoj8l\\\\\\\\\\\\\\\/fnNE1TkuZVEvQDgkLWufSLaKFrqkpUsm9jknJr9iW5qzgU0M0Dz25pNrBfvwbL1aiXXb1jQAxlXigLEPKvex3C\\\\\\\\\\\\\\\/a\\\\\\\\\\\\\\\/Z8l9LUsQA+YSpb\\\\\\\\\\\\\\\/kFs52Ydn6UfG\\\\\\\\\\\\\\\/J3h8c0SuVEeiBoDj8l4xdsnNZpcDhhhAu4hJxfVTG09gO\\\\\\\\\\\\\\\/LhmcQjEjmuE2U9\\\\\\\\\\\\\\\/OYucRM3Yc2iDhprlaXZl9e4dIBIGIOZ8GyGavMrFAmQagheacOFtCw84Ou3fn1hmFsY3J+IWPPhGMcjndW74g3BKOkqc0QTI5fk8okbimLGfVe04MdLGLL+x5VRyCSxopYET7ld8Hsivk9ySeocoZJywtB1XdXonRcuvKtxell07F0d0di938x2z5Mt549hRjATV4BA20ARF4ORLjuGV7I8bIIiJBsCfwsgZJdji6wcoKPDRMw8foAzzC7sLi+yUXv0V4SCsaol12ReTztbATOE9lrquYLHEn10zIyfKrt4W\\\\\\\\\\\\\\\/44xiyMVCYbyb6n9w6ZVPU0n0T1rrvE0\\\\\\\\\\\\\\\/+Sj5N3prqZPo6nF2kC+LFKt2rZJ7u+Ar3pxof77moQ+nXEIsp\\\\\\\\\\\\\\\/or2nGDFGwDHTil6dIUWDZi7WkXJtgoTUUDmz8n3O0oU80gjnQaOUtWv0Yfur4B9M0LMFk3cOHPF31lU7IFP6o\\\\\\\\\\\\\\\/uQ50HieYwswDLUIDcBw5ibfMd9OC38BRTPbD+MWwi4QO9sbNDnoAM3Qskyj4JdxLxgYdxNKG\\\\\\\\\\\\\\\/bQsquwZ5rRjvAOwB6vQjrNwoH1F7nYF9eUZawGJLM3b6lMEHA77n44cP8rr0v96xYf0qNN6U10EVT0kizV3BP59\\\\\\\\\\\\\\\/LbIW2qOoA3Tk63nzCPmWVCD1FRYIUXNdvxjlFcjhrfPozY4wUHuF0Y59QC\\\\\\\\\\\\\\\/xOBRT0c8pMIN3Hk85U9xMKsZRnG2xZ9EsWDZbngHqcVdxqxNoVzdfIPAkQXQ0Ql7wqPGR5jgPi8sXIQ3MydjuABT3skUuBXlUFuiAjvwpMFIi2OFP\\\\\\\\\\\\\\\/LTwdpPo5frrAULqUdYGP0+iFoB7mZz7qCyc\\\\\\\\\\\\\\\/c4UgpCZEnMQ7YauwcVpFYofzBcz6kdd3JOMlSqv4wxdmidRXSU60vAwQdnVs05kAM5N2cueuD1YZdaMiDnstrCLlGbL\\\\\\\\\\\\\\\/68MjpSmPPuyDkq\\\\\\\\\\\\\\\/b+xn58X\\\\\\\\\\\\\\\/txKvkYedyrAsgqQsp6FnmQjTQWALEIPek8MLCEC8x0KCx5zgEn7sDlPAzflrmT1Y5at\\\\\\\\\\\\\\\/bPZ9xCNATJimUMgwK9bB3Wxuyq3nBjHjgQkm7s8Ox2\\\\\\\\\\\\\\\/1YEin3T0gnz7Lii7feKOToJPAso3EePCyG5W\\\\\\\\\\\\\\\/smfZMpnVhS\\\\\\\\\\\\\\\/6YdnJH\\\\\\\\\\\\\\\/UP7ToXv3FClmbAAZ1c4TX9JM+5CNC2\\\\\\\\\\\\\\\/ZhyDbf+JFvuSNIzJNGtiezEQQH66tDnpB24UQE7n2\\\\\\\\\\\\\\\/wLl7MjyN421XccEE0xPDzY1MRWtOd7LRIowQc2ObzH58zCOizO4z1+rDpYBlRyNuU8OMhjUEOu5YOwmXmbtBGRbeYLiRNnXuG\\\\\\\\\\\\\\\/O9q2LCYy9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/qojPGEjnWjkGaE\\\\\\\\\\\\\\\/RWF2mv6mCqZS2mbouboXG\\\\\\\\\\\\\\\/WG4K4YqcQCUowNr+X3zMQAzSC6a+\\\\\\\\\\\\\\\/dECdCILUJ1HlBi14zSsX00NxOpVwcDfNlTfbCSQawfWR0KjcclR3n31uRL1Rwb08FS3yx9D52sF2wRxNK6eHxB98mYbXzeKeY3hwugtOZie+Khp6AWjGbxHhwJ7LyqwEStjZubrmf0SKgVK8GUv1y7847TQ2r55HbzIES6331wIWCW\\\\\\\\\\\\\\\/lz5LtYmY5MsEjnXiiTlOQT0F5d+niSat9hajiw2tMxdoC+aktIXyg9AFw+Dw35qGQzr088ytUzO\\\\\\\\\\\\\\\/ezCHPX2PrHYgAvOIXGPbJOyzxWHj1HakgHjzXcf1rgDofcVmhq6gQzHXMvm1DUnOjDs7GmQmzvI\\\\\\\\\\\\\\\/13nA8\\\\\\\\\\\\\\\/4n52kJl\\\\\\\\\\\\\\\/NDMuZlGH+BmyfxieSEhZahJAqGiFzG8Xx\\\\\\\\\\\\\\\/iF9WXtCOT6eiAFs3HoVE0IjmG+bBFNBmI5A4hysz0UUDfW5Olzb6E0\\\\\\\\\\\\\\\/FwkFFd+vruddXTncopTx18Cbz84yDF1pSUJ2h2JanKgc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Zko3DK25MGPBu1Z8dguiiQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022f0a0ae46dc94e6efcbaa3abe9a2606ebd5663d8548d416d6663c102d7d658e49\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A392.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A392.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0654\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0654\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0654\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}