{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022o8GQ2jR+yjk\\\\\\\\\\\\\\\/4\\\\\\\\\\\\\\\/l7hTrBB0cLX+N0TrSp+HlvgGc1Z5H0EQb2FJa9YvFfg\\\\\\\\\\\\\\\/B8o1KQrQ\\\\\\\\\\\\\\\/MI9yGu1nYvjhXw2ar0QkpWHqN+xtmn3uHCRf+\\\\\\\\\\\\\\\/iTgcbuQBFQ1Jb4cs3+YA02El+1mFfPZ2SjGXjCzk7VmqQi2oPJg3s35qNLVh0fj2s1aAJx2QhR0lRxdcQrlvCV6TDzwIYVeFt14Fs7jaA1m6KhEJcYWQ8mrJ4rFQ1BSLq1\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/1XgZY7FJbTBtIvfYQGUqNH\\\\\\\\\\\\\\\/gpP\\\\\\\\\\\\\\\/YqBPkOIoba6PgGc1MvPQ6\\\\\\\\\\\\\\\/iJRw92h1ZeNVoPqn+m\\\\\\\\\\\\\\\/BALwoIeQvGt2OoBS0PDGs1\\\\\\\\\\\\\\\/fTcTldtJxrSSSUvGHytuPRgeH2hGzzAXkrIN\\\\\\\\\\\\\\\/SXJlQzfKw\\\\\\\\\\\\\\\/jqVIy4mfX0RLTVFkzca5F8fhxcMMpo4QT7fMLdS6EWrMhz29hYoDGf38TJRpy4DG6pLrZgMEY9cPyJE7DY1t\\\\\\\\\\\\\\\/uNnj7NL5+Fxp\\\\\\\\\\\\\\\/Exj6CfdrAJ18O6gNVW2Q7iAR45bk+XbGq216RInAW8xEHqdOw8sE4WIXArjB0Vo162lnoNxvtG0al+\\\\\\\\\\\\\\\/yI\\\\\\\\\\\\\\\/r+uXa7WiGrMaheEJ\\\\\\\\\\\\\\\/OsuxuVUFNE9z8i7lqHwfz\\\\\\\\\\\\\\\/fJojZBJA9Muy8CZOAJV7rg4rhuHheHahMmeqtV2nUTDyLWk3Q7hqu0W7ueOI0ZZU7t40Ah+OG2VzWSEz2ax+lTwA7btEBgQdjAGoN7SldnLahbsl+DLa5PTAqurkJ+PDFOF14LnsOh8AsbBTDDPo+jnygxUX1PCRV9+rRH6tXbYcfswNRSw\\\\\\\\\\\\\\\/0aHFVaQ7S9Ug8mfUFI9JE+bhI1DbHt+GDZlK6XlQLvBPqfIiIoOkhTBjysCwn1r+Q9pPq7VgDPPLhSrq8q79TEgrYjTkpwfyGSOq8kP\\\\\\\\\\\\\\\/7tJ6Jmxb5eOfsQ00RFb+QuS6S1RTaJC+Yk3YFX2mUFKh67GsOz2s5CwxwznFAhDaHe11GDFB304otmmm6nwYoQz9IkMIUxuhv4hLGhxEO\\\\\\\\\\\\\\\/xutzemjAx0iVAXAOZVyo9erWljfMggEMLQiAx4LVKEyTkk8mdIw1LIkFUz+HsIxBvUwGL86P9eT4AusD0b7XRO2HUf3WO69WXiEBI2yLg9LslGQuv7vPDFBECE7jvDary+zQk+K3dwSixZSQ5iAY\\\\\\\\\\\\\\\/RSji169yV\\\\\\\\\\\\\\\/PqZPPlVQdxibYrGZnZA79AHDdoNx59WEauozFPA+\\\\\\\\\\\\\\\/xxiYlPr2rti1PWvYAUMtfFa6f9qpE6BA509hAvYxJ84vXINpkYzZmjfKz5KEE2S0aV5aBEJNtBZK4Zr3yi3D5Xk3XVDQDVMF2MswEteweCNEmhxJygWZhRn8UtFkuZtwqCU6pgFsXJYszBocEjLVuqRYA6C5rWB6t0AZ8gyRZ3SCGwVAF+nV\\\\\\\\\\\\\\\/JUyerpBp3ADsJJwhArydoN3yc6UFykgG4\\\\\\\\\\\\\\\/1sOTAthDa0lMGgHDLg7MkOmGv6UNq+uWUcWo8U5aQgHhulax+SrxV9v8QkAv44T8UccjR6V2bNn76s5PPqPWHH+w4KWcyx\\\\\\\\\\\\\\\/7N3mk98JPJf8WPzZNfxq+KnNVSHJHJvaubN9EqMVBOH0cqKY5wrJH+Jol7GUMKEx3+2+Gc3SNrGthdLkhflA7IbEhNf1v+GmHgTuch3XUrj6r2glLoKDi82Cj95gVCM3AQV\\\\\\\\\\\\\\\/PRIzp42SuB4R\\\\\\\\\\\\\\\/gmqdUQIctKFyA+HUBauGD75q314jnSTelU0Ymw92aazyxaqTKw7xgRfiJNoE7tJnBsXpy\\\\\\\\\\\\\\\/sgF33nWkX+H2PCU+0MX9S\\\\\\\\\\\\\\\/nJ79DyfzNcVDU7n2ZID7uDoiuKnsqc9Noc8gk\\\\\\\\\\\\\\\/r+MFTp6eiUq7zWEHZkxlaFYok71myK\\\\\\\\\\\\\\\/MkEkxjexldcYeNdjGMKLNsoktFea5GnHiT8jPna+X2rTArleaGH8W+DqSUT9pL8LTP2bBOAgkJNvsZlIlk6hyrq5EKppj9aMIftGSttwQ46LHgCKEtD\\\\\\\\\\\\\\\/XHAJomgHsnrdvZ3LAzbCHCOI2J0q8NdU3CIq3SyllLXpOVWKD9IBWZcrvqJPdZRaTnPcHnAga+Eq7UUhVdeQnpVUY0gQt+ceTL1y98Gf485do\\\\\\\\\\\\\\\/SkSELnfabz\\\\\\\\\\\\\\\/88WV0joZhvoNRxss7csm4PIITW2byrhwfnOZfl2oWh7L4cfrfpNhDTRZw+z0PzftzjgRTRWccpHHgN9e2qE1PSOavP0nf6sdwzDoTPUlKp4WaJhkshZcUalsCWuZsIVt\\\\\\\\\\\\\\\/pynTHBbJ5S4XfL6rh4XSr35ub9A9YhssAUwIZsI2JreGosJRUDgm+CKOiNpuLcnq71FfoQVFd0ZcpfRhVOI6oPwfqkqadmuvklU7LfqKpabjSpiJunZXp3HdjWtexuD+44Kr0c89szFSrrs9zIojy8E8jPb5W1SWwUpg0h5geHdCl90khyDQcIPj2J6sIkD5wVbECNuTTPneAEPZHceOqqGnArhIDSaow6kwh0HrHY\\\\\\\\\\\\\\\/DSA6p3svA18JMFV6+LduYgvPWaKqUwOOrk0xA\\\\\\\\\\\\\\\/J8ws1vlX2zBYmAZgDpVvGvjnuR1DvuBz7iGh2AnCgTZITYYDBwH4BuL6cKDz9e0duh8qX4Of2x68sBAA2dwDk2vdykvYKLhmaT+jNr\\\\\\\\\\\\\\\/DLRsEIoQjJGxDhnsYRw80EDrokG3e+BNSUeK+j0fTLYfX7JIc0vQysIx1NwZY=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022s2ufe5LlWhSMMqY4PHEcWw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022823e2a48f35e3f477bd8dd68a35c1f7501b68566699da015e0613cd7122183e0\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A85.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A85.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0140\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0140\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0140\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}