{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022WCJRbrwhvlhEQQeKPQrIVd7gaHB1Af9a43zvCEYQ3EC6QbWAc+A6ITPICBg5HOHi9oemPSnyJfn4fDDDcvmz0pW\\\\\\\\\\\\\\\/qbc+dWzlrc8TEc3IQBFgwsUmM0Z9dXsf56scbXAiKTk+0dX9wVx2Z6oCUS8g+wKHk4elqRn45fcnL0Lsfs8QT+WK2rg7CQRC0nId+BBsVofRnHTwqwEaWTsaI3Fug9A130jtNhbOBs5L89g1FzbchzN3TseH443dbxaGeES\\\\\\\\\\\\\\\/CxqK6I74uooeKTtLHciU\\\\\\\\\\\\\\\/PBG4fK84KUifTS3Gsk3rtm8layKUcXO\\\\\\\\\\\\\\\/xwOcAh57Gk5kU8yeHTOunxaoAZTBQT+zqw49r6NNs2TOCHD4wHRY195b2vphe7Bc9wcY9gcs\\\\\\\\\\\\\\\/RocdYdnDWufyQR5N06pESngMDwtJwFFADgtMWhB\\\\\\\\\\\\\\\/jYlKqL2dii1gmwt8p2Odk7WvSeWFx9OCQQZ57JlZtTUKZfbLwvuyvq\\\\\\\\\\\\\\\/LS3+3H+XQv0HhFXywdFkkValdJVvOXwsp27DuTItpk2FvzclDwqE7nmgV9UAR\\\\\\\\\\\\\\\/5pIS4EVi0RJsGfbUW9iOdR3ZIDrESBgPdfshr7AMybgIl+u5fDMnYgjJWMKm1Kv4RZtuc4m5Sdota44h\\\\\\\\\\\\\\\/WMUzcTMngZ3qmEFSVuj+vu78\\\\\\\\\\\\\\\/z1ZDXnmaLkGMHbizj5pnXMiOnpP2Ha7WlBoXoVwLr2q+7M3w6fsdF0vYOOJ7Bf5bpbg8aDhR6VhODiIrThXPIxMrOdsTXU9tvbI27L2Fp3PlBV74Fz\\\\\\\\\\\\\\\/6P1wS7BKemQiB+7hvtNmm6kr1TnuKsH6jnnd9c8JI7z3z9ZTTkn\\\\\\\\\\\\\\\/x2WBuME213I2xUFcajzadEIsCt7o39bmP1PYac4TtHZ\\\\\\\\\\\\\\\/cLZiuvAStG8Z+7hoTofUUdri72nrYC7L\\\\\\\\\\\\\\\/xtAmpowkpUeAswKOd1pI\\\\\\\\\\\\\\\/jUzXEYbR0M5uoQKZ3+MX1T6mqDE69\\\\\\\\\\\\\\\/296iIEGGZrcwzDbPYyUUUHHdwR98G8Rk3Zonaq8GT9dtBkJVkA9xZkmgDX13v8SQZStgzJ5wY52OQBc0ZkqIoOutsz7J1rl2XTHft8JePxAQLgMsQzi19EtHZjM1iOhmJvLVsq+jZ1dVhEc747C6Tz+X54FGRHA\\\\\\\\\\\\\\\/U4r\\\\\\\\\\\\\\\/LC\\\\\\\\\\\\\\\/fvxRlnj9llIuZPpKC1jXz+H4UE\\\\\\\\\\\\\\\/GkmuYB3gC\\\\\\\\\\\\\\\/bZueu8LX\\\\\\\\\\\\\\\/HQ8KBTioH8kTUyK9C2DEMBfNzKDpx+LI+Dhw4fM0BPL5y++mQgsucCjRxaNsC52xcySaTqtQpooCTNJoLSwkmpI9CT13D622YMfnig9ECUFj92qFPm1dUQdNnn8V1QVFJDIznl65Z4p4QptMHvI7Ln\\\\\\\\\\\\\\\/eRff++JKiXlEgUWtknP\\\\\\\\\\\\\\\/h0vw52pTP3GnOTy8VJHxZ3Xcy6JmmAV0pBnY4dWovegN3oQOGWbfYot+8RNzZsdwN6uqNNqS0cRdWRanLhV8cyKJC\\\\\\\\\\\\\\\/HTiC6saJX0z8m7ty1Hd3ClxJpd+uoa\\\\\\\\\\\\\\\/78YiY9dmeLnblsucvl3Ueb63brGf1Aj7MUnsLKvrDGKTB8c5xfalQSZ3UofTu1DPoQa4FWzLR20HlWu0q5JYg\\\\\\\\\\\\\\\/7BxfXHCjIdy\\\\\\\\\\\\\\\/mTI0zIrx4TlkB2\\\\\\\\\\\\\\\/JlBe3FemoRFh3EoGlqi9CpcMEMuo8+\\\\\\\\\\\\\\\/svXjfbwBtWmrPAbCg9eJgSkSaf2pq\\\\\\\\\\\\\\\/OljSqhUYeVW2Cuv6LXfFszmvFMkrmi4Vz717ZRkDR+BwX3FXbxOcbiMH2TRcIpHcZYLC3wjNmgX74FJAd2r1gLJzSrUZLR4eWaeh5ISfhSPQf3CUY2pShN5rbCfvW3j9J4CiAY7wQsAyC7pS7VuUlRvPTPtPGknMuV31095VWYgqWf0UXQxELd8WOvODoy9jzbi72cKfSzeSp8IcXzUKkArAIXi+pKRPGkrfGj2dvgPTdUBNgklsUEXCCLGhIZL9yqDnu\\\\\\\\\\\\\\\/0jdtvmp\\\\\\\\\\\\\\\/OHoI5Izl2dFsJrIrTa4OyeHkKpdAogdoDkOqLLbL01oFl\\\\\\\\\\\\\\\/vgGN2XmiMPJaoDvAwtJIcJ3P8uUy331uX7RB0cT2m+kKkKAxOEaWrgaDoC6ZXeLLgG1y9NcILKKsoWyCLcdSpxLOgWOM16Q+Ygy76PH2TpDLDfhddNyP\\\\\\\\\\\\\\\/JmZ82B0GN8Rgu5vHYQ6\\\\\\\\\\\\\\\/wKGvHNJ\\\\\\\\\\\\\\\/mcw1AjYFHA70922sGSsHmwZHUamQryRKd\\\\\\\\\\\\\\\/f6c+2KlFDyAIhKXjeOeP1cXi1OLL6F0pQU2CTobWHhL5JAiP5+lJmM4j43WXYkAR1RH6WotBOG8H3MA+CNzrly0YLUulfpsg+Q\\\\\\\\\\\\\\\/JqtdCp0M9hPKrgCUOfPGxSv4Y1Y5R0tnLLPeV9lnW9xwj3PEnNv4mpnBx3AHDMTogez1t8VGXcwj7y6hQqoCn05fXlIMduAkCaxHWMi2+R7cXbDPA1CuO+dIxf+Uirv6crZW5Wrgeu5LiC3Wbe1tcnEF8RRS9vDSQ89rHnSCYgvzyUz0rtNL97\\\\\\\\\\\\\\\/1oWkckmd4Iup2+7nO8iTAfurlcshbVIQDTX2+ong1yG1NlBGE1ibBRwn35Z2cUHbtdAt57Svzab2XvGmH4mdH6KXFqmeCFf6n+49yM\\\\\\\\\\\\\\\/Pkry+O5Dk7Xq+b4Murtfb\\\\\\\\\\\\\\\/z9\\\\\\\\\\\\\\\/ixvorgThEPhm3+NEm8E8Pzq0igC3o1uZGtSdfbVqsFeeVR8QDc5Go6AaRF3lzEq52fK2pKB11VPsAHI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00225tSaVVd9czqzRcqAZsvG2A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00220005c1d8475cc4b4a2ce62115e9c1b61c07e07abec30f0a3bb7d891fddbcedd9\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A9.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A9.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0017\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0017\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0017\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}