{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022f+rUk8R95lvtyNnwRP\\\\\\\\\\\\\\\/vQhGlFLcfSjK85+FmVma8CtND+vRmzNpeAxcMPGRYiEwmLeKMxxxB94D\\\\\\\\\\\\\\\/hcQ83\\\\\\\\\\\\\\\/Dgqa4dHLTjm8tVh7rjJTtcIcFTrPuAfyS+Nr+H\\\\\\\\\\\\\\\/KJOjpYsimx+a+nQ\\\\\\\\\\\\\\\/QGFhO3qK+e\\\\\\\\\\\\\\\/3jCzDmLSZJ2FWyt1jCLE0QdwZdfwIpPAarQwShphEWSI8XjMBlJvyXwHVX+UsYgCTh3jCq5J43FEHat9CZf4XQ5h2Sqw9nhWrMPokcRg4Mfo7AgM2SHYODCs6ko2kQAJx4pTGBhqqNkRXKVsHx1QTsQhOn4z5QITmsn1iTx2Qxn4r\\\\\\\\\\\\\\\/vMLsOdnH8JToyC1fjozBr3WCWUcNAc1ahgiMpuxhh1XIZFUJsxsuKebmTIh1\\\\\\\\\\\\\\\/vv+8ysnF9anbN\\\\\\\\\\\\\\\/++sfKa1HP1RVji3FP1ARpttylh4XI0oc5imNMZ3RNhQ4LnY6y8\\\\\\\\\\\\\\\/As7oaGW8CCABnCix0EKbNEJcMsCAB2ZM7SWWXenVHrYaa3mCBrPyxc9EeLD3IrX+ximJ9eQhAIF4ct2u3IF8FKsxJlfh5L7UR1V8gvR9t7RKxDm1wpF6OCpj6\\\\\\\\\\\\\\\/rp+zrhDkmlwjOmkAatT2I4M9OlqfHF0fejY7ZWvDawolONAJbYJ\\\\\\\\\\\\\\\/hVDVyQfbbScEhAOajSEWr+0WynORuK2lVDgBOMTd5VBNf0PGpMYpCqim37iYdLrNU5kkYVmPsoMGbTUGdAhRYQHh\\\\\\\\\\\\\\\/8OxxNRO9Tvl6EUd5AYGk3qg8Uyd03tsJqkpocn8QsjM17VMvQTdw1jraKygM1DqDVdszVC1BVhh6IMqYSQmMXiAsBNjmuw0lE2HboFv\\\\\\\\\\\\\\\/VtR+IywfVIIuWAXyqYyD9FQs0T+ojM+FO2DSqowjg1flZt5\\\\\\\\\\\\\\\/jphXrCMVUvPXiyF0qXfY\\\\\\\\\\\\\\\/u9OMLB7jqJ2IerJLJuT+zWrOFgXPU\\\\\\\\\\\\\\\/8s+wiBVQnRAun3b8yoO+InyPVumyRbgOlKlsaG+mKQgRq8YO9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/vlfafYxQtDvQTCwIGUDgsg9P11DHMpST1ciwKjTCeDwZQI56VH6JoQKtLe9CcyqywXmqZYneasqrpcMLtDBgL4RPdqd5PpSxSSMauCc7FKBax99EAB5jwR2Uiw7rl6jI1QrCLEgHqF6dEFvlLVrXPUb05qCFSnsMX\\\\\\\\\\\\\\\/AwCdr8UMV\\\\\\\\\\\\\\\/xuXPe2Xo1avARovtVOio+RLCGkkAd1RFcela9qw8XhKVgaus62AsJjPUTx+NMW0V1Uh4uz1Ymi8wGaR2gLrCF8\\\\\\\\\\\\\\\/mXY5cPY5eAno0Y2zyd6kOJDKUY42ziFDbSVKA4DsnvIzQyTqBtSThnwICnu5A9CIQt8zOaxjDPhyVgBBdzcwI41ywRKbv91sadBCdXGZVMmWUWxsWgaCH5gQ\\\\\\\\\\\\\\\/dLc2gRkT9cW0KkJkyd\\\\\\\\\\\\\\\/8HYuC0S1\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/i+aYMUmbwwJThcE+Ru70dSuSfitxRo9kPyK226TxkKq16bVxeU3citwB2+ZfnW5LCoCvJ2+YE9kldLODf1XMuvBoSYKgv55mFTBRTnGE7HuH7x98gto1DZ\\\\\\\\\\\\\\\/5Uhi9hJFJP4xAwcLf8+cuoX62q6sln\\\\\\\\\\\\\\\/oyHb037vTOT6dz79sVaUQXC6Z0cBT0b9\\\\\\\\\\\\\\\/c721DZVnccW7DyKyPDJpxcuQjV3OG9G1K\\\\\\\\\\\\\\\/no6nItACThh5ypVs3I4JfqoV2C8O8BkMP0UzuNQZ7ulBuAZpYmateMY8r9k90KlitTaDNyyIyBUgRqhyFNDieikHmZWRWxgOwgP\\\\\\\\\\\\\\\/8+3nHWSa0t+ZjfUTbqiq5\\\\\\\\\\\\\\\/A5dgdahdQcO+Y+hOPkMvyK7tounzG5QHP7z66Fst4L7GF5wXlxwSC34V3XnyNwA46h9Ri7JW8E+vfFjf+xgpk8AVbEbAe0H2Ar4t8dWuzQgysCzV7r5zFK7xdofEr75wD5dhkn\\\\\\\\\\\\\\\/uijwHAzyRR7Yiy\\\\\\\\\\\\\\\/QGQd1tP3X81Q28NTeAr0GOVVKdLgOVWnRFbPMU\\\\\\\\\\\\\\\/DHrPfYiqLHNQoTcfbM\\\\\\\\\\\\\\\/S7Es5iyQWZX4DdNtx2jXmeQ9mucK2gjt6P\\\\\\\\\\\\\\\/+i8w0YZ+pSin\\\\\\\\\\\\\\\/gK7RJF9W9mWpgHF6PmACQkCDr6U+gt\\\\\\\\\\\\\\\/LEmXMo8fhBIALFIoGfKxx5tS59G07QVSVE58Qki4Xp8HejyncVNBu3LdkEH53+iDBRrWHXR1rVFxgxirqbbtrSv9vaJpyrmon7bVBaKUv5ESz3vxcQ3R44UmEbPG+QqDoDyeMOC5J0h7lZ5s4LsJ+LXD\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/8mskC25W6AhjPOuCBoQH4qij9y97tVyHOyztJgiVqI10zLXZj6cgBUiLJxphL3kIlMHIckXBhqAu9Efwf8ro7HMIZbamAbcwBTdxLY2Vboa+FiMVf8hPLtXpgVbeyrWQlHRx3+R0TyUMCdrwdBXgGjTPuBdYkpUAJylS7NlbwWzW6GaRg3ju8uNYEVBj7xuBTTCy1bAsV9J2iFNm9nQGAWjaWTc3TpgiMKr1pNKh6NdkBm5xQlZX3ax5RolMCFnLEnARbHqFqlLWZtd8YEuTXWJfchjIc0RXptZwzd9vxav02OWrYtOQblwIqx0Hxx\\\\\\\\\\\\\\\/P05Z\\\\\\\\\\\\\\\/ywKlGu7mbfmrHMiyFmWNGHE2hp8+O2Uprr7ciQaD0iSjwi0x6WXeoxjjpH1XoTjf0hMbJ3Dbeue4UjafDbaArNDy8tLJHVpv4j19uxrQa3e4BLAC4OhjA0ojw\\\\\\\\\\\\\\\/tWU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022RI8t1UzZUIguOOKNWl2QZA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002268120faa9952dd2681d4957a22f9fae07b4048309b1f387322986502df1662b2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A259.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A259.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0426\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0426\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0426\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}