{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022hJAMAtjM0jC07IhgwZ7FFQcV\\\\\\\\\\\\\\\/G7QhR6pLG+E79WT6k361E1XhkxbFX9r69bpZr+FtoORRb4Q3P9WCB4nRNAu6T\\\\\\\\\\\\\\\/uc0qkQ4IGGr26udXKI9T+I5WRAe8ytvJt3Y5tjRVNOkKrOq+BimwljWF9pnDSMyBBRi1vhaXLmdW5f5IVX7zie8lyayAkz3tp+FLgtjo9Gz6j3wi0dM95Q73Ft3f9CwcoOGLz\\\\\\\\\\\\\\\/cK9bp8uMcNv5ktQAAZgtYGhB5\\\\\\\\\\\\\\\/pfPw+9JG3RUuIOBgxCdr4SLd2XjlGer5kPfBXUlvzRaUymoEF9YVSiltW+ssPIYOWLhdu0QQ7fKh7s7Ls\\\\\\\\\\\\\\\/NfUMbPvf\\\\\\\\\\\\\\\/ss0ltLynRfHdEphnxD1SXiDueg3jBS9B9xDQQ25nXDEYfrJNAvtTQuIg72aVL+L7SOr4cNZ7+BzBBBEcZ5lBrpBM91VqSJ46yh4ht9mjy2toY\\\\\\\\\\\\\\\/RwVLemtZ3vJV83LIwiehXxYuSo4gABVJS5fKLCK5YbqynBZ+oyH4tqszytViAa6s3JhsZegUUuoFFrD2bPuZv4Mn2nhxln3na7Y6v+EBrmF8YqyGdXueHIX9HfR+84e6RFT0mrAYGIyvhG2szH6eoGHwQmvejPw3YLfxt7sHfhxUeoe\\\\\\\\\\\\\\\/QTZPx0rmyPwOkbY\\\\\\\\\\\\\\\/CyrRZs9CIc5GTbxUvj7yfxBPjM41uBQUfMk3liPNN9hZcmCFUU9oWsZSaNEPLAqxH\\\\\\\\\\\\\\\/Nplw3\\\\\\\\\\\\\\\/wFjsh5FmnrduDuUeSYLnULvq62yM8dSnr\\\\\\\\\\\\\\\/aIRf3P1ZhtFCsflvrlHcWjhDsMobpcvyMEsrV2mhH0i6nuUgqw\\\\\\\\\\\\\\\/5wnt+aHxqD1KWfwfpkG4kpogOSSJORaZjEs34MaICL0\\\\\\\\\\\\\\\/VfHv6onHQRNu5Dk1xD85RCrmPNKlHDUN7dgIYl0kRr7f+k71hIfB7G+BnnjkcX8KLGzP1uwaUfHYaHZJGneqWVuk+yVf2SJexaliM9Lf46arV5d0oLyiB5Rpa+OcK2bOpl1G9wdJkIvtcejEZrPJ+mtDICFmhiinh0neTfmm4mk7jnPTWQTpjQ9x1OFKnTA5orzwszH\\\\\\\\\\\\\\\/ogJP7hZJ02vuEBpKKbdm6moNpbbA+TW4ImrzPCqJoIRRpXQipmRqyJy2absv0rRr2qRAZJoJOZlH\\\\\\\\\\\\\\\/IjiXJ9\\\\\\\\\\\\\\\/7S+dBom\\\\\\\\\\\\\\\/3N4VQPWandgaegt40tAfERbF889x1XbdhgMZYzsZ1Bw0UCJOciB8BAN7\\\\\\\\\\\\\\\/JHaRGY6M2WhrbmlHv3gzpp2FGbEKNJOtXRAJF03eSE6JW+rrguwlw+k2uj9s2FYCb9+ymtb0S8xczUkJcirOWAcRdXyfYgKUKk8rtnPcxCGPdh4S5bbejVkr9wM4Kgj2yj+fT+PmH7wWlWLpkmztHiO0sACLM+65YKFP1+NfiHalRljhmZU6DYcCsvQBOOQ9vxbrGsPXKgn0qRiJFGTd0AUOtF5\\\\\\\\\\\\\\\/azDE4FtsVxY1XhSveZzTALE3+PZKfZd9EIQ\\\\\\\\\\\\\\\/4bvFJWGCv4DKAPlYiidgSkePH56ZgbSDMvL\\\\\\\\\\\\\\\/SET0kxIqBn2kTstM4tqQWB+d8bCT2gqnfz7CBxhuRckyMbqEUlZTZUj+bG+wFUWfM5kv\\\\\\\\\\\\\\\/OsOOf7V1kYaDfZoQbwY0Rc0JKJEsl9amr5eLt3tiBNlocVLyuaNCxq4MpnshJvN8b+2pzgjIquDhs2N2xvYFk0eaTNLSGS6MozDwS0Guv3gyRBS5Ji5Orvb+pBaloj34VJM66PvvHwezvY+2fiLfptJJZjcqBJXm8i\\\\\\\\\\\\\\\/HNeiKM61xiuJ1NAMIwqGXNF3ZkoN5dPwbul4UAbCkLj0R3M0WzKWW2FNPMOCyNcwoumUcIICYgZA82rFrbUU5HnqzHPV4UGtofa2ncUyxxFUVoIjN4+oh1sThvcc93fTdBFvpAyq7El\\\\\\\\\\\\\\\/GucXzWQZnOkuFlKqHTBbRu3gouWXQOykWvst6dteHBkbMW0vV1kFfj6tiI8S\\\\\\\\\\\\\\\/sYV5y9mv+A8j3VQrRrXzz42dOFF6hQKv\\\\\\\\\\\\\\\/XWK1IZDbvyE4c5ByETKQtmCkJn8cNRXmE\\\\\\\\\\\\\\\/SRPQJlu+4q5Jkn7XJppUQApeUhhSZsLTzyUingA+4fvSdHxu1rxDgLkMnSnUGbz6S6DrJk10Z\\\\\\\\\\\\\\\/1UA40OG6fWEtk3X\\\\\\\\\\\\\\\/cJuzXbrXaQUpCL81kTgCbHpmyg0X0gvz3GH6hrB\\\\\\\\\\\\\\\/0L8NZFO1GdjgUe5G+GDomx\\\\\\\\\\\\\\\/YWKDN1q3Ojv7PoUTVv2yPIZs0vMIc\\\\\\\\\\\\\\\/SQ8Kmy94ke+s9i\\\\\\\\\\\\\\\/Z+EWIuYCoLZHyopMSlZCCDexhPvjRkus2PTcgWUr\\\\\\\\\\\\\\\/HdElEhUG+A4oqF5QWnmsi\\\\\\\\\\\\\\\/cI3VtELUZanlk8I\\\\\\\\\\\\\\\/L5+Q8jbCVjV0ZdcxEVZjNgrpLC7givAaa1BnHkkx1tCMlJ\\\\\\\\\\\\\\\/wdMiP3sx\\\\\\\\\\\\\\\/a3jBaQHTC13qhU7tD4jpaPfELB9tDD73ldyiIzzz+HU2wB\\\\\\\\\\\\\\\/gGxmXO\\\\\\\\\\\\\\\/67pQw5AnqNvatHvhwxUXyS6lWIEHS8eC9620GTUeFaethclwQIKBqihghdVmwB+rrCFiqvrhOKZrE9P\\\\\\\\\\\\\\\/+ZCMV+d53ApwJBPxX0WBxkeuKU4DeObM5mZ1gLA7l8tHuiw8NRXkBLjMaH73QemSRfzobDklDkD6SqK5f+zrUExAc4nFGkSBoXI3TJfpG\\\\\\\\\\\\\\\/48VqdMDArZa\\\\\\\\\\\\\\\/Ybat+GXPT+XIDgjC2XgE3y7AFv+FryNux+XA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022X\\\\\\\\\\\\\\\/lllPlqjt29lJZuTxNJLQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b9af9c118932b37124b464e823041eb033aa3780a95f0c6e9730d672ff6b52a7\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A25.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A25.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0042\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0042\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0042\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}