{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022IzwzDIxHVCh4EMEamp+pXDPs2SLi8m7QMzuerp2TWbCwxp25opsif9ATgeEPiT+6OIEN4uMUgRkmHJ4U94nHC7XkhQRPB5rPmrPBAAtG\\\\\\\\\\\\\\\/ifWrFup13Cnj6RcHq4T72ezP18ojfND8Y0eVrw86fPGyIHrW1adlxJaOjrFfrVxPOKWtjcQHy2PhhIh8ltC1hzmo\\\\\\\\\\\\\\\/lxe+iZXL2RrEz+Swd4aJQVh59Bm4Yj9I\\\\\\\\\\\\\\\/hn4wNqqYvmvMEPBGEUlTBYnbTB7+5WC0wD2AvJbVImiUSw3DWn8Xrf6jpx2pfcrh5oDkccv6b2YvMUo7la7uf958fjtHRmkwvciuW6BhIRtz4+ZIqAfee7S\\\\\\\\\\\\\\\/r443MFgP0Qngrh9SeGoEB14WYiCBZuc+5vAv\\\\\\\\\\\\\\\/6SnY5E3upMPpDJSpziTudPzho5nNwYKqu0rxXbc3cBfA+jZf9av\\\\\\\\\\\\\\\/aATNrcVNWq2AOkqlQhA5LKJpj9CNB1hlE+7MCN5OsFqszos96DI5lB6uG8vDPN+BN\\\\\\\\\\\\\\\/owikpHStN1V40kyJsRfvFK2JE+LjsqSgiJ95TOAazESxGHbslNW37rAk8XNXECJb4mYYz8lHeEfDoCGOz5pFFPF8tojOHaadmQo1BzzxJeGwEIRmWKsFBXnTZVUWlC3GqmWO5RHIYKoIMmil+jaP4kFeJ3AORNMg5BHuGmHu6hS5I0gqfZ1v5hQ25ZEFX1A90dLaMgjLHZxMAskXzdh90ZbrHDrAoZkbYckIjrnt7M7eT1\\\\\\\\\\\\\\\/hwjECSAi9EsFIsj0p1m4J+ZIoQb53HL9Zd7xGdvE3Rxy4WhYoRKmf1SEUm\\\\\\\\\\\\\\\/lFprJHmH6woZZ9PvNwE2zpdGKOvsqkESt0q0QFJIKXcNdcWJX09Ekc6Y41q1vPW4KjsdtkdpSPTq6+mWJsGc3LLSaw187PlgTyVmGTaUOXFYWbFqpiw\\\\\\\\\\\\\\\/pRsiH+4M2EOOPYPOF\\\\\\\\\\\\\\\/+YshnFIj73OBVfC7X6sYD14O1iFnJuc02g6LxRF5Wmbof\\\\\\\\\\\\\\\/dx4qizheQytp2RqFQ1\\\\\\\\\\\\\\\/bbteypbAFWsY3g5KDP0BkRR2kf3GVZjH\\\\\\\\\\\\\\\/3ORpA3LxI\\\\\\\\\\\\\\\/pNqfD9tixuuhYAWv2kTM8acN4FE3TJ5\\\\\\\\\\\\\\\/hZNLKGl+sQZUjXtzauqyc1VtTQou6i03ddODppun6yPTJ\\\\\\\\\\\\\\\/Sg3jZ\\\\\\\\\\\\\\\/4Bll4ljvLQQhlxmw90O7Jq56QYWqivrGQdRaK9wUE7HogU9864hpd9d\\\\\\\\\\\\\\\/C5vYa15qJ\\\\\\\\\\\\\\\/+dafzJNayKjcZNY90or2VAb5h6sRQSfdmejcvv9JdhjQJeKny6\\\\\\\\\\\\\\\/FpyCEx\\\\\\\\\\\\\\\/WNe2DlQ+P\\\\\\\\\\\\\\\/N5K88dH8t2u4pCDDVx14EKAGf5yXVBVniyBho9eR+4idR5EfvipQ2jAl6RYwP8hKP33UJKKWom+NfG1IhOhdSOn1dEjLCS5Vxlcngpwu273gEVanINcptlbEZILK1KMc67e5gFEDH5dF5mNjYWcGsaEJkplA5BEO2b07rctJmxzOfEL2XuAhI9WOsbFHeS1MjEC1zQI7emqcKf5pMJSC1cn2rqvbxORLFbSCRV+va2cTpdvGQ66CWyltHe67uFjNsAV50Yfrj3JY02p28+ZhKM3IprFV13iachjRlDlMuLm2ChS08NkN7mhkHOZf85md\\\\\\\\\\\\\\\/hg7\\\\\\\\\\\\\\\/F2BMBHqas0Cs+qb\\\\\\\\\\\\\\\/mAAxVtXTotX\\\\\\\\\\\\\\\/yd\\\\\\\\\\\\\\\/JN7bTIAiDxFx8JO2qGljQGQVaB1aLNwhz3QvLMX6M3T9A2n0D7e2wU3h0AZ0q9q0tMr2jXp7ngzoi+4NAgKhQT08ypfqrYueUZU8IRP8rXDrAtD4qGUS32blFO7OhXO8U2YePJlPSf753oy9L5M4bhWT9Ia3GTqP4skTESjuD5tCrex4+B7+A7G2dc+INTX3zal6\\\\\\\\\\\\\\\/T+36WHv4znSgfjHB7x4EXFaUenkszoctGD\\\\\\\\\\\\\\\/FQ4cnxAEdOeAT04OxBUIw+lzKOcKSDE0CEoHHa8aZsgkA4t\\\\\\\\\\\\\\\/yFieYaoNTCKD5MMcCPhyCpxIldIYGBxuLWhgCh76BytSaxMoa\\\\\\\\\\\\\\\/lNYGKqhEvgXOhgUX7M3v9lrxAk3YAMxXSqZx8++QM9p3ESacwN4epO6DoB6l7NU6mYMBVHZWAt05BjPnKDwqEEkdlqqa+DfpO1YZAP4e9O0fHIkoZsGnp1PX4eCruVYJDDnAmouAn8oKscaVH5xH4vga+FpmkaKB2erPSkbdPu5NXoHWg+8nJrQCOYxGZr2V\\\\\\\\\\\\\\\/9LeZ6BSIJXCfJFGkwVEREpxTpo+cgBXDVV6iz42KAHq8Xh\\\\\\\\\\\\\\\/sdWyy6pFyflwDbmIMBYBgTSZhA8LSQwixXlYLGMMS\\\\\\\\\\\\\\\/W\\\\\\\\\\\\\\\/eYP6D0TxRb5smCC\\\\\\\\\\\\\\\/gTm2+83BBS85+td9g7V6CdpCwpWPysJA+jnCETgWlgJOUJIPUCJBzXHx1y+Wx2D3zdAESEFBGYI06CThqIMlBWftx4pHOvYfA4o3O8jFC6vKqrt1Nh4Sy8Dyfcxtl9cNvVYZUWTbOs+unsuY3qBHWfB+cNebbc9hqr9HCshbxtLT\\\\\\\\\\\\\\\/MFFuMo7ycxmAZ9UcUH+3zJ0VTAmjePHL6d8XdWs9scmX0d9rPzY39eTdWzYYD\\\\\\\\\\\\\\\/CpK6Sv7eIv1\\\\\\\\\\\\\\\/nte6duJ2JUZ4iSnjmvud1I2fqFp7iT4EJsdSFIIcmwlFuHXFaABCxroIzOTEgKXlTEGTN8RHB8NitQVdG0JTZ7iYbouMsNao6uZveJ4T5R0N7U=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022bJJaRAXFxgda51VxcaNVxg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b1b6156a3c8f518849bb62cf289c141aaf39e483ff6db89c5f5159109aea957a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A412.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A412.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0687\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0687\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0687\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}