{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022KBJOZsfV9R+aEoy3mZXDt+dbGKAanxwlu9eJUsHhmRN7onJgOr9gcyN6OeGfy\\\\\\\\\\\\\\\/PqygUdo0WBq6rnuIRheyU+hw\\\\\\\\\\\\\\\/V5AVLT0x7OzPs9lmHtG6pTjR1jliBwuljCQvfjcwGF2kmxXg8ng\\\\\\\\\\\\\\\/6x4avxCTQES4m+ZZChHhdmRDxGNgI5aA\\\\\\\\\\\\\\\/VDaVqzArmB7B6nfY7yZlbQDvvy+Av4Ix+4ogOss5i3y4JTtR\\\\\\\\\\\\\\\/LGE0s0Ejpj8wTyjXI4vugOYF+y\\\\\\\\\\\\\\\/P1mF43JcDBgBJ5WX+loGgXmyYtWmC8Z38Th71dm2mkmGo9WjCb+WDDmZ0X\\\\\\\\\\\\\\\/5d9wmd1lg2QoCDqSZBiDYPhzxT\\\\\\\\\\\\\\\/XZvI27Z7b5ymuikI+7FBO1CNj8QnQrI6vucPP8N4QLk0GDvmhi2FfjOYD\\\\\\\\\\\\\\\/Ls+yw\\\\\\\\\\\\\\\/71iarxLAni3l64qOQc\\\\\\\\\\\\\\\/pntwDU29KpQ+uPjBndBs4IavtfNPXS6kusLpCIR2M9EHGVjpMJZLRii050j667YAlYtsDCWAXE\\\\\\\\\\\\\\\/LB\\\\\\\\\\\\\\\/Ljp3nhG2tvRSDC8mAqQvTJCRiJJaiZrp3UcCykOLg2k\\\\\\\\\\\\\\\/d0BYl6DW\\\\\\\\\\\\\\\/uphO0gEQ5IHMcEzwtIQYA7bpM5Q0avw\\\\\\\\\\\\\\\/DxMoRzvkemIW6sDMmHjkd1AojB9AGFgmJGzyAwKJqQ80U4W4IYHfXEVTeervFYYgqySQkTxZojJl76zA7DxeeiekPcKMl\\\\\\\\\\\\\\\/Y58UBXQiIUdosAh4bKXAywWvSozD+EDR9VjUbqjtKig\\\\\\\\\\\\\\\/RSKsq21KXEk9l\\\\\\\\\\\\\\\/vnYbHBMwYnm6oXq\\\\\\\\\\\\\\\/j\\\\\\\\\\\\\\\/6xzz6DRJP4lZm0QAKKnp7tb4i7a5Y+uHwUl1MERuu08SkhTY1xeWYxisF15PLbAMTSf+yalq+vz+xvf9BazsdmVqLRIjYGtNKF7TGkEX8Pt4Q+UuuBKtQdiIPE8Q0PupoW7Wf7le2Lf8RPS+dJsv0G45+gHgnsl2xHKRjdj0nyFkE3HKaAoR38gkGdPBqL6iAwrJuGH\\\\\\\\\\\\\\\/pUWeH\\\\\\\\\\\\\\\/iFyezFoI3b8oXUl8ONU7vuOEOKw4aj+QHJfgZkv13qdrBhTZrrbsGVQ1gxQzj6VgkJowcoL3jdtZAn4C5PKUIdP1A49nmcWhjv3tSCxrSBHLKlvqERv5F3Yh\\\\\\\\\\\\\\\/GIRpuRYA17cLZvJO9m61nLfsmwjqC2Wh7+6KgR6dnIKUZpcsdWqXRRfjtr28+9PnlzBuMKmG+t8+GA9s1P16lCaHlbLmlwh+fy\\\\\\\\\\\\\\\/w2sObRb9MtO4GZ4iTWNU76UbmYzhu3VGSgagCsgGusALXjbdxw7qT\\\\\\\\\\\\\\\/+NwfVlg+Ghuz9IO6YJdA8OlwTxiiDEjgjWMhJE4qWaP6HA1fL77lIlR\\\\\\\\\\\\\\\/aXkvrQkzEIIGnMF\\\\\\\\\\\\\\\/fltc6H9p6lu+6qZg7enuURHm2\\\\\\\\\\\\\\\/EuKiCD0DEac\\\\\\\\\\\\\\\/cciseIz2yXSgo55F13poMyaMZffLzKVkeMmuaNhIw3jcrLU+mq4HUBlV3bxj+SY7yr2fhTqRGE71HRKpgUd4LJGjZL+CBwrnsY4qT1il1EL5PtQtieSICZiFagVl6p9BhZU9AFoNnz5JexeCsw1dZVKLGkAHcVX5\\\\\\\\\\\\\\\/CwHpze88bB03sN4BqxDYXGCX988wqjMD4xO1ZctHBYP51kD1V7qoSWOuu5cMpkkUzdDMzdR\\\\\\\\\\\\\\\/60ESn9O6WyMs18hhiMTuoKqy8oeCtENTcB1Gd0sDxdOd6RFNZg\\\\\\\\\\\\\\\/EhzDq17EgQ4wmC3w0jgrX1n\\\\\\\\\\\\\\\/NYpIAXUfvas6dSnA389NNeUY2DdVVaqyUa2UB9w+AP+XjhfBiO+8juAz5QQOVfpSokSSUiSE34\\\\\\\\\\\\\\\/eAwjgZrYYpQpjRJWSCMnvXpSNwSwQWPOSZ3NSuxS\\\\\\\\\\\\\\\/0ynV851lU3SXuP9HMHC1e0Ra9vh2x\\\\\\\\\\\\\\\/z\\\\\\\\\\\\\\\/9Q6fjyUMe4yVDYMpJ3aYHX834HiDCzLGDVhh179sS\\\\\\\\\\\\\\\/PR1QDkSH4cpQOxTBO73T7dfGNtVQnSWWs+EtBYKA3rvm+SYIZ+itJhz1ZaV+12nq67i7b9OccnFp7JfLUaALuKM7BULDFJI1yl\\\\\\\\\\\\\\\/i3oQO4+s2GYv\\\\\\\\\\\\\\\/iGN2UUMKjX+L4YhnZ2I0D5otJDMLQ+ucFPlQvtTzFEq1AOMfVi7Foe4LCg2BiuFdhHkHuAHakUaks9T7ISsZYwolrk8dJNfgEiQjo64DHT5\\\\\\\\\\\\\\\/YkomCyW4JT4vNc6LcmjmNBTyv1s9G+DkOpdJ3XWQ+gFYtx3k\\\\\\\\\\\\\\\/wEiTV3S26nvENK7kTv5A9zdY\\\\\\\\\\\\\\\/CO1KNH\\\\\\\\\\\\\\\/EoXDQFHAeUoche5GW1r\\\\\\\\\\\\\\\/Q4A10QiiYCgsZxaZxcZHBdyycMH8X3OTErmmwtPLYd\\\\\\\\\\\\\\\/6g9\\\\\\\\\\\\\\\/P+PecHXvzg8VXsvlXpA1GP71i0lpd9B+Z+efnNaNfnsmWPdbyTXpMQF1PpRimakdZ97+xYaiQlvk2dDgRy5yrf\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/g8vWNXF9p\\\\\\\\\\\\\\\/iSR2ioHsl45vCmmcRKi9R77g0LYkrH4jiqDFI0kpSFobZNRDwc3O6A8+JvaQHUYtCMok5PEfy2CLk77EsRcRQ3awgckn5CZuUaty9p2p7RIJQGEsmkzdPQc27jbwr9D1FJycrV4vUxO\\\\\\\\\\\\\\\/0RJvwqj2VApWLN2RVCKjpTlvgG+lr\\\\\\\\\\\\\\\/3b65a5AFK9vo6s7O2NE9xfWR3T0TUB7c5wybnOlS+PYgtWyO2svboGvYqxO7UNsLqYUFQtmSiYj8a5sNm1SpWSySXdAApYjWaQTmUhHpOklg50\\\\\\\\\\\\\\\/mCU9Xuer249RkrmhWY=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00220WU1hHIxMAlBQhc6HdF81Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00227e477e4db57e1472b1dc0f7d9c814a8f4e9ec6b3d91bc943aad259ff28e877ab\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A300.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A300.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0275\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0275\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0275\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}