{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022aDB3HC4zAoWCbBqkE8NPnqa\\\\\\\\\\\\\\\/wKF29JmOyErc0rAWH1y1B0QbhJXuILiZKXDcGvCNA2Ft3PQ07ou2QjDd0TpBPuQJkAoYi5uIYdd4QodMH7ExZNSNDLOe6NQyGYCthfBVuUMzTv5ifen43A39aJArl6XPhFPda5+M9nDXOAUpwwpQk46KD+ZHeFfI\\\\\\\\\\\\\\\/6kvXQ1W7f60KjNysKW28AmCQV4bpd7FKC9lzyvtsG4tDEraJVvTKNO8xB0VEOssJiJy8MCdgJsBYxKhMmdp\\\\\\\\\\\\\\\/tC3yHoussYpRThup59fehYSRdyKfWFL5YnjmU5ytEF\\\\\\\\\\\\\\\/KM4QPq7n6m\\\\\\\\\\\\\\\/By6tVpILRnua91Vv7PARsrZZNmtr4P0Dw3k+ZDo4U4hbq7Z+BqIq+eve18w6boAipZC4VM8ObSTgggQMf2Y0zbnTcgnPe\\\\\\\\\\\\\\\/3unMEeriAV1NtchmTlB+O8ejdkBmkisndTRxX2ujcg9JbAEC1UwRRW4mG9CoP+M\\\\\\\\\\\\\\\/djgqRmyXnY5AQO+Ug\\\\\\\\\\\\\\\/4rYe7JpuqS6rt2z0XN55lwZpUkSOI6VXDc7LvUYGMkM91jPI0ctvyNCSdcDCvO9M049tNrOsUqBiP0zCIc9gXOjYb6ED9zdIsCla5vKPCu8+zQzNRyJtDsE0qOXBkoShT\\\\\\\\\\\\\\\/N3i\\\\\\\\\\\\\\\/PqsZ2j8wA1BEPnRq4cVGHPqnhj8vKSet2X0ZPcxrekY8gQ7\\\\\\\\\\\\\\\/9yhGw6qWiyyKBTID5SJ4vtjmdd86af+dBM1qZcHQ2jwqsa7tSHYrU6flDyv+rH3TxU+JRdaVPfmIBfTSply+81s4DnOrByvJbRW6XQ5FxYhMzMgHOB259w\\\\\\\\\\\\\\\/5\\\\\\\\\\\\\\\/6W2HnfJznA3KXnCvelsz9SYQYFW4ODZholMCuFlV69ncK7M2AT5E1R6SNDjlxGudOG3IPgQlSkVqsfXXElnrRMmVpasIvGktl+SZMAHqE3LdOwyxRyukIRvUId2PuN6PRSRMdYs2ANCrH4htvdYfPv6reoPiSnhEJKqM1+tB680DYJQcbnMoapwVB7QWLsN3PyJ42kFwlmIuTgBnDVpH8Y9Lz3Wr5KL3YxClhx1LxWkupAIULZkCDdPdtislN4+lV4fxSXA5il5C+EcbrWPS73AadonQQLhNVxAarJzRmQVFSGFYo2UAEV8ricL\\\\\\\\\\\\\\\/i3s+MRJQY9xFEoVre\\\\\\\\\\\\\\\/NWlr1G+X6qAh4fxmZL6uZobtQHsj5wq5GJoemdHQLw767lxbywI6mv\\\\\\\\\\\\\\\/U4TLy9UHInLuMKT9Zy58jRuNJf0yl6mizAoY4SxX\\\\\\\\\\\\\\\/mPzE\\\\\\\\\\\\\\\/uBf2k8\\\\\\\\\\\\\\\/BDnImOVh72gAtvzhZsO\\\\\\\\\\\\\\\/Nm5LUwQL8FlGKv97iZU7uyCYNdJfjKNxjdi8ZPVDs5zf6UJ4dgPBxwVgNK65J9ff4p8gwNw5dplWu1b5lTZUz99RgPuR+xJOAZET3u7PbAFqbFpnuB0B05N+sU4Hfrx+3OFnXaAfu0luaagtpxLQ8iwxFN8tcE91rZxehMJxBgI+euEO4R4++KU9TgBnoPlVQQFmSmKZTjBviFJ+v9B5S2P3HFYCP9nBh2OiEZOltRK8bBWvy5S9tWW\\\\\\\\\\\\\\\/lMZ6KvmrQfhZyABESM9D8ay0hUr3Fx2xPHZbnzw0zlPLwRVRMxRKs176fO+gMjB3+wzIydm8GvBcrv0lxZ2SkqCb\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/YlGNcgKl+BYQQLSFpEzveuMPgw9l11TI6CILS1d84pofdB3nDN9PCYnEgkyk\\\\\\\\\\\\\\\/eW9dnkhQfUCMAKWw9KTd1ks394MCl1sAVMD2GXlWJzTcqHrUrWFVgHDju3xYAZHgh5bgHLe5oOmNXQ3ws45p0jZ90LKy0HDf4vmffza3OrHVwVsKm3xKvpVxgHRd49aeVykf5h\\\\\\\\\\\\\\\/t1qsymd0KtwU4r7b5OyOCfoxHM7CDlhf0d5qK9JKNnUHTddYc1EyA+7ERTXsTue6uFK5REyNhBvINjzcAtnv8ujBJT7pTqxJszXQnrnqwKBTBALjW5urk9vao9Uf8F5BW0p8fsJ5rptaDqgFAWQ1oOD+1iflBFeKahqb+5rxkAzxlifqOS7+6eZVlSRY1hywOMQdI6cTLO0WxpiYCA3q2qroSJGanp44uduLlt6DpnyhXoUgFOLsGqQnqEZz0TXChu0zaf9moyAjCFcZt7Hd6DJvfskGRqfFpmK8gC81FWCeImofzbB3W4rbMwYne4gzxRgZ3GQGvWwfV6\\\\\\\\\\\\\\\/FDYrV6KDIojCtBJHkTi+uShC00AS2aMXCurfb6TLpykUElMhc27jAoRbHNJoAXadEPTNHXRdouFy9MC6CJ7gPD1vqLPmjLxJca4BPldeB5htXr6Wwi3SRru\\\\\\\\\\\\\\\/4poJWUziHHMKAfsHjcFyc54FxQ1toR4khMMXtnhUe7uI0DY7lm2j\\\\\\\\\\\\\\\/1rd3TmsM6tKRhYgfaFoaehHMYFBWnyqFilPKRUawnJ7kT5HH4oledO7g7s42J36W31vfwot6LESqnYzj1mzBaB8WiE8qDW6WmXskBKuuaN+LvPC+u+wRN0yw0fsEMF6VUVp2G42q29AUVDzrRvL7e0whSSN10KpTqxkqXx202qahLpKlRUTOzhVbCehB2Bel5XpWs7jY33a7R9sQ5MK8N3pcD2iNUnuiSBUx7GB7vqulruUk2bXI2rv5Ij0Y8yKBQ\\\\\\\\\\\\\\\/gj7TK1Xl3TmVmr1p2iBM5LSIPOc4FechYI0u7Dk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022fJweUaDbQvuy3rJDFoXeCw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022152de95778082ac3a1fb7042d280e8c0611b5bb7fb5a3e1c2c9b0e5df4319ea3\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A496.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A496.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0829\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0829\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0829\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}