{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022RGqHUZH5pdE9gQrldWGm7E46jvHWMTtv1\\\\\\\\\\\\\\\/wVHMVmzARnYMejgoe56xoEIaXIHwOJOaZkAB4ihFlG2i0OFbZxb1cQjP1MR98y7vz0d9bEZxd1wb8bvKPjsYu2o6BNdON2N2djSnOAmh5RQJEoBpUr9vEOa+TpVbq7b8ytgGnK2Ba1Y17XSf35WUhrjBjMP4HndpCTMGiHfdrj4tNTMk\\\\\\\\\\\\\\\/tvNYwhCQDzabg5RBeVdGV4bWapEhjdhk1\\\\\\\\\\\\\\\/45IBh6Hq4k5wwAta2g22leWhSuWxix61rItoBgQIN7ywWcAXvWAOnESXseVbPgtp06D00Px8vV1xnyPIs5Dg3htmqLmaEsowHLRZ7lefokbU9PWLIegTLwjdyyHYt8\\\\\\\\\\\\\\\/0+4gd2Jq\\\\\\\\\\\\\\\/txSG0qFw5F4Gh6T\\\\\\\\\\\\\\\/oMVk2D5T491bqKJfk\\\\\\\\\\\\\\\/0NTnXRn4mEg\\\\\\\\\\\\\\\/eT8HRuIL07C7xnmiEMu5OnfbM4B1W5EOhInFtfVie\\\\\\\\\\\\\\\/Ix3iomncvtBMThC2fyjiEo6vkIhnqGX\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/4VOIA7cONPwJF54e+DEU8HECbNVNmP9OlDiYS8h48zfQ0n980NmQK2o+yef7OZzKcW3LVOzCVICvYA9PI7JdvQVFBQzK\\\\\\\\\\\\\\\/W8Nr6lp4dgpsVWSuDMDFd0Vk9qE59HZTDtgagc2vmyHno3k7P5hRcFQSCfmDiUNdAH+uOZpY+CnY98ksKgE9k63wKZEnnhwihZrlksmaveWTyJjw+W030wq3nAfDuzJ4KtIW5uomzwY7wmgsbRzu81aAMoTj8WjImHN1BAZCXJD49RIjOB+1AfsKAsS1qP8JvvmUxM4019VPeHNI\\\\\\\\\\\\\\\/+Ndj+H4IB33ymHGDLzQaWqFLp3SkU6MKSGOzqf+JR0tq7RlZgrEKNgp4\\\\\\\\\\\\\\\/uPm5VFWxrJTw056aQMFhtPy174oUiH1Qk23sRjEb3pgDh2BkdjJjdEbbhT8K\\\\\\\\\\\\\\\/2hl1KBRPwjUhN7s4SHdNn+RMggipatEksdTgMm\\\\\\\\\\\\\\\/GxTYmAUkI5n5023Km2Mapr3KpSlO7qaltIosa9qqAi77+1MPa+BVADxuZ1gDF1uSAtIc6pSi+uX83yHNBgGRb35\\\\\\\\\\\\\\\/vHHpCNAZtbvsJXRtSxK8Xe0eMqpGc1GJerKxCYsNtmT7w\\\\\\\\\\\\\\\/nrjUimrISDTCRC8GHGYf7KBKMywUn747RfDmuQgVekDAuXMpTYKvvz2IeVlqUIU26FLnA2KrAtDkx0vgW\\\\\\\\\\\\\\\/AHLp1kdRmRWP20zA0DcXxqhOAtI9rXfn760vE8hJmrRgaAJ85BlqZzwnaL+cfwxfEzxmXVtAY0DLPiDt+HOmXt00BP79k7V9E7a04AdOgqj\\\\\\\\\\\\\\\/b2j28cJPednk992uKuHG8N0Wl7rliKuPiTDNqiDPrHmk+8S\\\\\\\\\\\\\\\/idtn6zujzyXXpkhMynDJa6GzDGJp1E7sRJ01L6xf9eo\\\\\\\\\\\\\\\/N4VxzZQWxaMb3FCu244XR03fDh8c8+25nLW\\\\\\\\\\\\\\\/8re+TYwPCsY7CCIVQGVRnPJFb1sZfcK8wxeMCag6QuOL2UJaxWXnhcI+ovZjVJummA1lzibl\\\\\\\\\\\\\\\/5+9eEd9ZMwstbB8J9zA46FfDo8lak7nlqufaUaXAM+WIH1oTMJStR7M0ZQVpRvPgliDXDnHZI8HUuGd6he7afByWSeSYsxwkYFVlYS5HvMRAoHWosgX1pO9QrhdAgtQPxl5209PdXyiPpfWdMn4vnKXOqhuGiYGo46IGh7av9lZRxVifV1GGoC+fhUrLYjoDyZOlzvdQmLyiC0C+JUM6iuiutdlAbZlmdk30xwIZ9n7aQnezveJvzInQQkS+KtHus4ZE4AAdHKbQxNyneTIYOOZ2pPgwTetEaT4C1jvyJAIwMk1y\\\\\\\\\\\\\\\/ycJdGRkrou8ZVxOlvLqen9rc7nit2rQUYiOpeh5ue+fCuzWvduXe7FwAp61VZVa6NV2p69ze2Ovp3rD3ZsD630IMiRksWBcapJ4X0NX6N7d5tIEwl6eBREZHH4d5W9l7A5Tya0ExgziWazsc6DdgZz6SWpbM0zMmDmvLORP23WEcFUe8SXDBgVzwQP6Pe3CW8x0TCiYMC8Cpz2UcehvOUoP1UUVs91tO\\\\\\\\\\\\\\\/Bb2aMh1+Lux2Ocmh0kj9UEe3OlGU8XXU1g541PUq4577JxGW3cZvfIrvT01H+gX\\\\\\\\\\\\\\\/cKvuCl0sS358yyf22PuXQtYnWnsJeIBKAipBLHcHyLD6k3Ub7Ob1vUNZ8T1FT16oaL21bvQHv6JNbE3tsTPrO0aN+Z1OzAggHD9hdDb4L2ictxo21DX9nhxceV77C4twiBJuNQhG5gqw9GnYpdsGbom5O0snbURniyFeNlmytuEtXsGNwA9mxV1tWLjoegBXICFOQ4GgYlvVWUomQZMw7sMM+BsDIi9xNv23ui69PafZId\\\\\\\\\\\\\\\/az2RdpoimaJUYMUZNQjq\\\\\\\\\\\\\\\/RbR9BCz\\\\\\\\\\\\\\\/rtyphxj07aRxbS+29Rc1YmAonyjdlKAceKB3+CmEBk\\\\\\\\\\\\\\\/X8nofZl8XYnD80Y408eBlgXi3FLMVYgRuvdBlV9q79yQLBi4xwrVUyMgq6SNPho9mcPWQNPEoEH944vnAGqZFT3EpmyIC3zfJsf8Q+kB23eOKdf96fm9JWGFR6XqsKEBsT9IS10gUm4LuAbElwEhNJ4ZeTF8Ggv74+uVlV9pzMiCVqkiyt1tvNEb8CuElcNeJ3yxY6HLb6I3hUv8IPiU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022a3So4ihxaD5O1Yo3kaOJsQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00224ab596da1b583e165c4738634133e8e98b86e442c3055824c7f3e87c4c620fc1\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A291.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A291.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0475\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0475\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0475\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}