{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+KacmYCSHovTVJ+NlzjXY9wpxxgqPtk21a\\\\\\\\\\\\\\\/K2twVICNsB0WkX2RAoNtWpozLY6b+HZ6O3EvYckB7bzRtPHU4GcXDvsXVp2CKjx2ZIRUXA4azDjzpp6CvuTh1PDKHxgnyJGtDSeBx5QP9D1sT+Vea2ygtJzCFzE49QEufX7A56cabLL\\\\\\\\\\\\\\\/iz7AjDBz+0O7KfCBGiKrcnGXVzEkPsZK4xYnYalHWWCcbhl+ylY0OJzX\\\\\\\\\\\\\\\/hteSlRvQYt99ZcGzT8THSneXSqCmN7TCoBx9yxAgHy7VGT1FBwnTUUrrCyCYRZTHSbmVf1R5nTqRAdJxPSKzgCWAhsDo5\\\\\\\\\\\\\\\/8jYihKdZ\\\\\\\\\\\\\\\/0uufqYKuM2pQWRqmVp0K3iIjbFwUMuAGuEQkLucXk6Y2RiL7OkpvcTH+QEO14AOMxpd859TLNXk2FNBb9tIdRrUj3PzrusFh8ww30FTmE0AcrFAAKe66pKYKsZlon5IPtXl6kfy9jnEOo67zc95\\\\\\\\\\\\\\\/wEhqxO9p7a8JhERkM\\\\\\\\\\\\\\\/8s+g+9I9jo\\\\\\\\\\\\\\\/rJOxfN9QrbKjadxELYZ+LoOf2sXcM\\\\\\\\\\\\\\\/SptfRsGUPB+dYg4HQCpE5QsnnAlEUOFdwM8ShhzWQaxjHo3hg2efzV\\\\\\\\\\\\\\\/6uCzSCujTtQfQpAyZriTAWXEp06GQbWm8v6Kyu2lfo1eNpFhCLUKiPhqN\\\\\\\\\\\\\\\/wah2Q\\\\\\\\\\\\\\\/s6gbMmTS\\\\\\\\\\\\\\\/M\\\\\\\\\\\\\\\/AH\\\\\\\\\\\\\\\/mmMFttWbncMFA8c0yEkeXMx\\\\\\\\\\\\\\\/8RM7fFIPWmI7DcQwAc\\\\\\\\\\\\\\\/4t6nudUHWXLOTrsKmzlcQfzVyj3JNAwIhIQyMil9ShAWvJ6c16eZdEnvhqFzItJoNbx4RyTiVnxPEDV+3IPD4dSSc2I5rKzIHg2zxSmtVB+xs2cGyKsZCKLxny\\\\\\\\\\\\\\\/ogVRUnsd7hT3c0CU5NpGN6ciZDx\\\\\\\\\\\\\\\/S\\\\\\\\\\\\\\\/W2Qsm+lNsFM4JXztajB6VwHn2vBG2IV6ytP9neHfe7f674f9udfvYC6rGvCYJsOgES\\\\\\\\\\\\\\\/s1GHMS8ijbDrOospO5g+0Wxr\\\\\\\\\\\\\\\/d63QZ0YPq\\\\\\\\\\\\\\\/y8e8oAdC6HTWpSVr8Cnad7bGksYKWwoSeFkZFO2ZIarng4Z1jyNk6bNT6gmbF42o9cZgNMzMl4M+YfRzu0AwrX4iKsOgdwRVhpIg+heZB7tKxjT0ZpiXRCkrKxGgy2z280GQJ3v4JI8Y4u6GsaX1mvPhvgDawczFHfm7GYSdBVINsU4Jho1x\\\\\\\\\\\\\\\/2wcoDfCM2OcCwMEKEW\\\\\\\\\\\\\\\/MDSiEy+T7E\\\\\\\\\\\\\\\/91ynbyY\\\\\\\\\\\\\\\/gLGEzpXBb519\\\\\\\\\\\\\\\/2vh7iuwxc9K1Cy0Ut9eLiLy05rKA3YHctsusHGH+N34eg4OQk6IEZ7s8RqnHEHkR\\\\\\\\\\\\\\\/D7oEQdIT79mGZ55gqd5+ZGan9XpwCeGMeAwN82ro9pHxIagwlZ9d0tYob9Xocjt1Btz5ohwP8d0AxkLgZp8Y8U95uWK3Huufi+8Ndg0ykuCqKot\\\\\\\\\\\\\\\/Xh48+7lv2izSrf1oSjT6xDUQBJyOerUbc2FWv0h0b4CkWKnXE\\\\\\\\\\\\\\\/R4Mq6+NpRSM4AnBkE6ZKk0fUJl9kx+XiPioyb2yYlMxE9xomIaxvafst8HCIK8SzU5x+5hsEUi6KHkYafRjtAG5uO\\\\\\\\\\\\\\\/ZK6bH9HYa7cqN3SBoxGMBj0kuFe+UOB+fv+wpCvnaNpQ4eX9QVMysATKoHv0KEz54RgCnNZhw0VtYAEqJBK4R1y7DGOS5c95ULwo0kNrqrbBxWzwuoxhT8MMmxs05KDaw5TivEhc0yxELIx9rUsHsIj9AmMkwxVmiEeCqMM9urHzpJZPxnOdRuvjhLKiMBunTrANXCzB7K0xatxs7MMd2yCRchkQsAsH5teIzjIxjuap\\\\\\\\\\\\\\\/Gexz\\\\\\\\\\\\\\\/sb6RMAzujPSJoEzCsjv4TN8nwrA2Qkcg1rRHI6LGOLnVEA\\\\\\\\\\\\\\\/+l17KPM9hCMe19Ck2mwIZNvirlMTP5yYcW8tSnqRpKTxvOQOc9cSmIi0QqDzHrOnFb0kNWAinoRkECuEJOTyu6mQ\\\\\\\\\\\\\\\/CPLrrmU4x74IVpi5t8t6oz+yckB4\\\\\\\\\\\\\\\/e8g5K5I9ylBD11YPmdqj9g5EM48HeqdVOxq\\\\\\\\\\\\\\\/eQuxuLnQZbWvRSGEsRPfAFeJH4KSwTq2JUH+c8rhJ4EulGriQSt7OTX1FL90waAJmEYYFbtqz2foV+TVJFnVrHNtie0zCDAVZBjWBpS9e5S8jZp2OW+5wUFO9x4lAB6EPNs6TvCSfXjO2o+Bj6z7yjYcYuf\\\\\\\\\\\\\\\/s6oBkPexPyvGspteUIrFcm5EIYUbAssff6biaiYqmpnyA\\\\\\\\\\\\\\\/X+2g060drQIVaabZCLvajZTUGKCEjJ+Q\\\\\\\\\\\\\\\/BGZ+7nVzWHb6UBJW1kqRwJKV7FrbMZjE5Mu9WYs1k2N\\\\\\\\\\\\\\\/sDQhjGC\\\\\\\\\\\\\\\/Kj1i1DAJwCSE0CaSCdGkFKghzpVXrltF9ATMgQejxsp+eBu2bm8FNumU3UlIp3PzsinSURtDrNF0A5TU6c3WR3FdOxITWHkWu9WF+Z3NTKmxar26EYK556rQNlAjp1UNSwmGE04t5aP\\\\\\\\\\\\\\\/cq5aHXpcpkLwtzW4V678W48miXN9Y0FV\\\\\\\\\\\\\\\/QXLsNA9dyLCaYC59nApPvBivAULVotk7OfFFdb1zmWkcBSwjbdwy2vSsmLPxfhupaPuJjzUYuDkv5A665VU5jwGIOvFTzG6ATeLIEGpPnNChjLIuHupoV0qvg\\\\\\\\\\\\\\\/WWyHJwgDPO02sCm8w\\\\\\\\\\\\\\\/QNlrNPLr1KNsCms+ULSaeyki73auuKVUNIBpek=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022IOyyuwnL\\\\\\\\\\\\\\\/9uGqtP\\\\\\\\\\\\\\\/9JJXBw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00229b9e695a2489bc57f0f4fb131a5e9c1032f8c64b263760aa8b05934307479c73\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A50.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A50.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0081\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0081\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0081\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}