{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022d4FBxw9SAQf2IcNErwYdG0K0+My7DCxZbOBV2Gel+NxQnhPFVVi1aC0LCw9\\\\\\\\\\\\\\\/YocOO3T7xWJ8fMFF7\\\\\\\\\\\\\\\/ktDhdPFNop8Um1ilp4UsM\\\\\\\\\\\\\\\/LeNOpAtWxWRjbaHDPIixcPRSs9XT0bojZE96bWvx8on2wnXOQphD8tPSIM2FdHpGuKOEcNM7ig3pQLiwiztuPzfkLOrAUI3Pno6h0A3\\\\\\\\\\\\\\\/YWH37JNlKlxgkqRhEt+EGACKZf1MCFC1C2ByxYUNZhJMjGpBXP7R14FJPR\\\\\\\\\\\\\\\/2vHfcfwd6VxbE4rgLUFDN1jbsqa7c4O0xQ6o0GLT8IiQFf+ebWqmGofJDOJGQb1MiWG5xNIjz1xGCfnqp+U0hq0UUVb71SO+V1aH8EBlNzFcfqowHOqk3s0VJE\\\\\\\\\\\\\\\/jyycwtJscf4xPYEdr65194YUaocj8PsE1zZMMk14j9kyx1t916gLq7gNXvuZbRXlcB9AC46YBiWcK8KW02lq\\\\\\\\\\\\\\\/u\\\\\\\\\\\\\\\/Ug1yvKkhsCso5Xxpj\\\\\\\\\\\\\\\/wzZv+KWJWOG3TYqZ5MfhOsi\\\\\\\\\\\\\\\/YrmW1wMgAiP50Oh\\\\\\\\\\\\\\\/yHRdRg1E4y+XLpx48W7zSePQLj8oZvQdckfAaFQgoAaKB+S7Ss3+a6UDZSozS6TIpXlukZw94fp7UGNqKriL\\\\\\\\\\\\\\\/+rXQsMBQTHUMiFlGwWX5wDptvFqWjjzRv0RUcsznDPmawpidXlQ3Xkt6hRQWtbgHFXAMRfiVKD21uF7889hcaIn28lzJWq7yre6DiTlG+RjjA6Q6U7ARpT6Itja5zY9oKqELPzt5BjD6YB2b4Kn0g3ivPfPbB+0\\\\\\\\\\\\\\\/G0hlp2qM2S8j6w8gvZiU27TZXxKA604jCiBB576uPuN66lMQjeshM94pIn5e6UZrDydoQ2enAWrClWxaRH5WBSyu2EHVPff9NfBYn5HeJvgTxMRf+imq5wquwB2oLkC2eF3GIRn4210PkvKOt\\\\\\\\\\\\\\\/cg4i9uiYYq6JTdQTElLEJ5Ywr6MoCNNIo2afDZaiUkIZui\\\\\\\\\\\\\\\/VoEcm7+7Ox2EsWmN2fZRA81lwJp6i\\\\\\\\\\\\\\\/cPivz8TaaG3MVCaJEvFVt+vFZBCuKv2Q3Ccsrt2hw1V13NunEQxv7f\\\\\\\\\\\\\\\/Ys6xzSzVF1ocmP9fg\\\\\\\\\\\\\\\/aXPkOhqkRH1vWCCGMvQd8h7KRXKhDMEsL4CMTIbRaCyEJxJCVq73QQLbcxPUKBXF7kNE2qT\\\\\\\\\\\\\\\/4KfwkkyJLYhPlGmy7\\\\\\\\\\\\\\\/7oript+mVfYkSgucbyUk59CC4PUi6Y0UTYrgjlZBNQ++zLLyy5\\\\\\\\\\\\\\\/mXxwvbpa1bLHTFZLxRKbr968PIXHpB1+ZHbuXHqD4ze4lMBoBH9SHBlyFwHmQhNtMIISSR3ZxE9t3Ux\\\\\\\\\\\\\\\/l2oG+RfvjOELHhtfvNyVd4icfjx7GVqoXD24gJQ9Ranlhm2y19BzZ1GQZZ7PRS1fEs8UdUiZCA3MK3D9KqBkPMXm4R9agCKv\\\\\\\\\\\\\\\/TweDh19sPtBv9g\\\\\\\\\\\\\\\/9+OyUsa91yiK294lTbDBrmKhMCpbkdq1NGmgOKgDS7cW0sPypluI8cHPl0eBhDjzuc\\\\\\\\\\\\\\\/f5G1a7RRvNSM4m9d0h9qDBkb6C4eKoj7QLuvCf8LU8CMtvVYGOazGZWQzqC6oaam3mwK6WpEAaQpZ4Yq9eRZGq7d4UxYKHfL8RjmpZPW3LZFv8gzWYl6toh2aDI8jib8tjE5DKi\\\\\\\\\\\\\\\/BtCY1BEHleOEQeR5HhBc7\\\\\\\\\\\\\\\/S++o4yFF0ZxTNRyP0XEhV+MBNse3OsRDvsBNaefheav64p4LvhARSpSnILRZ9XUHYgChlvjM3NcLDw1pqwDc5RHFoaSlftzxh+8WUTbn3I75gLQRLl9lVQzmu42KrqM3TpNeRVpWL2ug2dsPbiguYtpLXOauasxO6UJYJ4JsnPoHbCbMnWBdDrV4T\\\\\\\\\\\\\\\/we6C8GNcRvvPJZcy3i47tFxU3x3cjhj1UXYEKgPHjpKMY67nf05iwplzFGxlRQ+EM64tVw8xwm2Jt+rRrWspTS4vrjz1FQZrvCkLK5q2fh03mjTQYKoCqkOWbX3Cdhw6Yskj9vsHkvj\\\\\\\\\\\\\\\/ZceGcW5N8YB9Zg0w8\\\\\\\\\\\\\\\/sjLl6u0g8I5OomOBfPaNZFfn8vplqT6uyx+8x2kBrK+cqfDx9EUDpOhJpV48Is4+5VPN8pDlEIg4jlUtHmyhO1jDSD4\\\\\\\\\\\\\\\/34M9X8UbhXmNe6qsNAKRNWLE9oX6rBcFDLGCkQiRWeQm9z347hgfotKpCrTERzwO46y+fT\\\\\\\\\\\\\\\/9bgk8RmIHeqv7yikkPcr0aUE5gh8Eog3IqJm9ghoqiATi5N6w9+daPsb1AAPol242pYq9+WRci7c9NXu+6CAqtxhaF8CA9V189fl5MfrT\\\\\\\\\\\\\\\/tYu+OhBx4oLGm\\\\\\\\\\\\\\\/ScaQudVr7gcBdCsTlOS5frRhLvbTcdmzxyoQ2MHKhb+ykhP726MA2SikWmUzTXH\\\\\\\\\\\\\\\/HIngrneVhdBjJDGDD\\\\\\\\\\\\\\\/qjxdFKphKJCsM6rsoZACXoeRdZ1YI\\\\\\\\\\\\\\\/L7dqLzRq584tObflMtFfCVqexS+hRILZhrC6hD1ozInHx1FHZLCctK5PpXiFAMrPMMJ83eskzthowTCRHguQyPMAr8KIU+81FKXF7uQalF0yv8yqBMd2amJjex1HGZGAHPcd8zpAvxBe5fwkscNZ656eTfLYCKqVtT2vullXgNyC56B2dma2s3Q0eY9Xcn6rIfKtYG2LV3x1Dt9oWj6k3tg+BZpiZLrI72zUADB+d8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022B3WVsnRTVO\\\\\\\\\\\\\\\/t0ee9X0wyAw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c8a1f4b7979e86d2bce043d5041490565e3872152fcf9d33b43f99bd221748d8\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A439.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A439.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0734\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0734\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0734\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}