{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022zPM5R1iRFl9yC5TYWREmFLFnTo5PZ4hjM+wj51dyaEjidcwJf0gMVngFXQakq2rENCkAT0rarSQtgXjyr+fR5jX8cR4wyo3pxJIq153\\\\\\\\\\\\\\\/gGV+Ye8OJTNGOEZ8tBx4exEBOfNAOWFpS57pAVv6umLLutiZjM0QUQa9nhqGKKQ5vfgKLLvbr4xWAQGxnwcvvsnBS+RvEm0napHZg8IxBtxMs1Pr+fsl4bF1m+gLa48R472jwCj0yX5Z71n7p7NEaGgUmFX3s0EnJ\\\\\\\\\\\\\\\/wBkp7XQUtUJUPIbdYLBD4hWUgZFvH\\\\\\\\\\\\\\\/nNMjXtYufj3sWggWaPyFeISshFVAEdjP5YJIwxe9ZAU8cJRpSe85sxHTlSFunxVZ75L33KN8VWWrRmOAiUuZg0S4B+AQLTPok1+Z1v\\\\\\\\\\\\\\\/oL7RBpj+4AyeArmzSLJnhT7eQ6ZN0QamRBJ9W6npxYNH071Q7IQ4TpU6qwemDAiuiwCsi6OXYudw+4j3SFl6K4XqQU62FaeBjhwse9cFwyZ3Uh4VZGVJVKegO2hjXsO\\\\\\\\\\\\\\\/bCuFoPRd4YpAuU8QaTTGkie+ItL5LhIcmeHqxcRr83rh\\\\\\\\\\\\\\\/GdP\\\\\\\\\\\\\\\/PAsNWHAaDmDQQ1\\\\\\\\\\\\\\\/diSRe3DvmLGC+Lt82ZWEHWhyjtgUa0fvtioWytIntufsU3oPtOW0GDI4TbGdtyk3SLXVgzjqhkbw4UYp7VLnUAtjqzU+grgXQKIG6fCyepVzPHkwbOhqEvenFn32v6vNNH90EJQY0+Zi8ZIHff\\\\\\\\\\\\\\\/o6r5DMyRyUAO7Bf4GFmJ0OEjZh\\\\\\\\\\\\\\\/lrJOUDjj0D\\\\\\\\\\\\\\\/fEAWgUshpUCPbiHaTWb6aop\\\\\\\\\\\\\\\/zUdLvnO7uxGODjhTNISSazSj+QSSs\\\\\\\\\\\\\\\/AvaaUNCeUdoN5UlwPRG7rz+yDwMFPMcuhR0SLLttZg2rc81KeWkLMB3OOKzur5TkiicUYHr2pv5AvLoY\\\\\\\\\\\\\\\/GSHGtHN88vtnn5tJZcHfqlTgTA8RCZDu6k9pqinVYi9UJdG7FwDmSxDsmYEOb22AJC7cA96kFzlupKplKlRJWWn1h+vpet4w3p0tMLDM\\\\\\\\\\\\\\\/M6Er9xq27XiR2VJ+UeoC2vWzTF9uuAuzkC1xK5Lml2igyHMfymFrbhX29dmVT0xR5DCC4AxVxZj2Fy66opEDtYzf13BnpNTH4l\\\\\\\\\\\\\\\/8B9Q5jb0XVb82TYAVZc0UOmBue\\\\\\\\\\\\\\\/GTxu\\\\\\\\\\\\\\\/M0LpGzz\\\\\\\\\\\\\\\/KdVGHE0OPbZEuChnBvcFdaTRThWRFL6YaiBU9G70gbRwm9fx9CEZ3Pq08z8r2Xj+XiBV4zWbpL4U4xzgqWhoBJC6tcN\\\\\\\\\\\\\\\/gXH25hf\\\\\\\\\\\\\\\/F+iIHZuocyzrKxVt\\\\\\\\\\\\\\\/F3\\\\\\\\\\\\\\\/d++oBD3s9v+TYutKtaJ5E8he\\\\\\\\\\\\\\\/M6aBXtSt1xEneLa+TuIQq0EaW\\\\\\\\\\\\\\\/Xpm\\\\\\\\\\\\\\\/xs7V+y7cIzHI+JBFHBfWlhozr9erES2FYFUg7YJXurrPKwR\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/EZAX0DDRyyC1W5cZpa9mWTVyRY+1UyYUq63+tT4QyFZYOqP+lUestz+OAnY8w54Wm+bTUkKhahc0Mvr7Kd+qdEIGAt2ELEwA48e4THm48eimp140n5tOM89pjGdjLntUJ62ztRlroCQLyWLW5S2w3XEHishfwak9VrNwGBPksSa+p3y96wjs953kTZQNpG+ERcKEkyeG7ilcxcvccoo5WYMF1GOCQ7tDUOUJ6hxfYKQHbdiA4LQLUfk9ssNlWHrrt83nl9i\\\\\\\\\\\\\\\/5OqAQ88HuDjWNc7HLdnRoIjuQSHQt0CzvmD4ukHqIJOJXbs4ZWsDYM43\\\\\\\\\\\\\\\/6c\\\\\\\\\\\\\\\/RRER9+IxHun7myElQvIbDFwy5UwGbZP9BVHv2Fr1SE1u666gHYweIhxSV0dKAFd1akQRMj7aAsW7oO6+dLSwHHPv0DPFxKp3APigv0rLmWmESQTLuzBMJuzE9LbeEHzBMOfrAL9mW5bEgTslE9paNgPiijWlYczpLN+1agswElqZ4yE9SmvCZTihFfjIvD71ISbEUl1wMiuhHdeSAlb1mgVpb7FV8EN\\\\\\\\\\\\\\\/rU9xuvYNcRMcSgj2\\\\\\\\\\\\\\\/JiE\\\\\\\\\\\\\\\/wyi1pG+JF+zGFS7eohmw+hiuXir2u3gC5RLQ3oWaYh00c83K9SW3UeETtT2HqaWQLJLx5dD1rl8Rox0yZqEsWNAy\\\\\\\\\\\\\\\/AWn\\\\\\\\\\\\\\\/PVBsMD\\\\\\\\\\\\\\\/eN2gRiPdgNpEPFNYKJaaSMWgC+8tzqrH0E1fBNnpdBV8xwSf53S\\\\\\\\\\\\\\\/wKxGLTAYyJeqOi2yNK3cjfWwgEj7M6AS6l5nBqJuu0BLOBOj9Oy476kkTms0TQ9Vwt9eyNAfMErY9aZ4J5LNRCt2y+03flQq6yQc5WdWqNey+tw4VAqV0Yw2nPAJlyoiSPP0H5ys0gflmzS\\\\\\\\\\\\\\\/SNF9TuaiLMJid1CKYuXYzmudBFo2wLkrqGvxGD9ce11BroLDhvzC9tASYU3tMWSgWPSgPXfEw+BeKKU+SwmEfDwEF6tpKFfVdWeW\\\\\\\\\\\\\\\/yhyAksxUqRHJJBMRHXCS8gD3dkZeblQ0uv\\\\\\\\\\\\\\\/jvmJeiZ2Jrn0KZ2F80dCaDoj+esVNWftTs3\\\\\\\\\\\\\\\/H9EV+d\\\\\\\\\\\\\\\/9+jCsarO2E\\\\\\\\\\\\\\\/Au0s6VF0RE7rpO5X8Exow+2K\\\\\\\\\\\\\\\/uq5kAFLkYHLPQJNpW1SyEsSjr4FKW3RgpClezhQ8IuZx56B9n2AS1SZzDBRvWRFCigNcJ8auCyEF3FqtMXlJmv1YoNFR+g1ZWmw0HZohv306pTSfK9ZW6omvg97JJGWXC6qT+D+Q5ksD0Q\\\\\\\\\\\\\\\/k=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u002254XbU5fuib9hZtQr4\\\\\\\\\\\\\\\/BDjw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022192cf9357bd5e309010dafb0f6fd7dd8d8ad3d9d5635dab29cf2ef9c5332ef34\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A361.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A361.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0605\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0605\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0605\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}