{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022oLVHSPttadWKEpqMbcPFwOOR\\\\\\\\\\\\\\\/hzkV+Q9r4saubTX1rgyQxVV\\\\\\\\\\\\\\\/wkBaiwvm1E0VrjEaAwMssPfbZrzg31iYyHpcYl9MOFPZp85D6hZF03JbBNfmFthqjOV4bV\\\\\\\\\\\\\\\/NbEv\\\\\\\\\\\\\\\/n37gOgg42DPDPMuTvm+jNIBUAhxKcL1ovLOIR2Bv2YFLqFIEzkAuSGLobizEx7VC2NKPIrTL2fT9ZzkyM8lImJenNoEZSk5jTQnYchrQIjaLrEEq2VIF\\\\\\\\\\\\\\\/sCosYuwVqj\\\\\\\\\\\\\\\/6DW+AsAf3mVZYseO1NGKP58TEKQ8TTh\\\\\\\\\\\\\\\/roN8YxA1EjotAbFc8\\\\\\\\\\\\\\\/H\\\\\\\\\\\\\\\/mTcXfU2w6Ag3Vk\\\\\\\\\\\\\\\/yLWKFLDWVxcUo1FcILxOHh2fbSpExKv20dBI4GTEGvMNH0FvBWxRuFh2vMFTdtOhJFEheLYePOevMp6ctJvWwNhwvh2cdtj086MhEJrkw91AI0S1iWqvileCtHciMIxC9wbnBmqplMukRtP9CLJGyXhjOBLdcWqd3cAZUBcthQ2zR5lCXPuiXczpgD+X5E06gs4uydDr7mrdpOd9JFR8awESNuJws352cPH0iFP1LNJE1i07ih4qk+D6ilNEUkYZKOq3hHwoc3QGdRA78E7wFyexhLgq2hjsEYPTA9bAcH44kODFMWHzm+RKE900Rdv1f2UYe\\\\\\\\\\\\\\\/4y60xYL83vojO93SXTzEFDJjrLwcC89IXsPksHhYg2Isg+DzmhaFVwcuvUyyLVHxDVpLmqQN9QCqkhQ2PTwpOoc76ZaU9Z1rt4wv\\\\\\\\\\\\\\\/jkM9CXG\\\\\\\\\\\\\\\/obI70N9v30zGN7CfyNW26qZieHOouB9rJ5fEcLBN9xLvZm7LyxyJAJ6x1nFvsuU+SBoXZQn8oFijsbePPgpyRCFTpSt5IQL9w9YlRQ44n5TFQTmJI44gNkhjmLf2N89m5masw+lEDtDDnOCvgpCgLCrImSPEAVpRoTTmVcU3dt5JcDV+45x47Og6Wcx2j9bLsZh1RFOtTMMmZf\\\\\\\\\\\\\\\/tvIiX3TRAu7100MTrq\\\\\\\\\\\\\\\/yo0iTY6oddyXpFKoYMuO9P\\\\\\\\\\\\\\\/k9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/YxzjxTZP8y6h2OYZPmLAPSI1aJfZmiioUy+QyITkJGoGHV8I6ggZgyyQoGItG9aJE6HZPa34VvDUQc9n9jwtdYs5ke2YgrL8aa2ZpE9NouFxDBcOPZ1ZhAZNTpnLi6DwfPSCLzkncvW\\\\\\\\\\\\\\\/+motgRAUMNUgnlsvbyfvj7bYyRRXRL+vXYqgfAZIM1homTbqz6EZP+7gkLxWFdxIF5YLsyD5oHapy1BKfSDya2iZZhvfCaiWftMVbtw1f91j6Ju8XhiUgNZFCWw2Nx9NNwowXJoNIk9QLBtVnDkXjOw4iVrI8+ElS3m502l\\\\\\\\\\\\\\\/ffy5B3FlNAHRoEDJXfKLRPEtWGTUirKmDKHlMV3PHNSJPVCBkEfa8wyElFIu+SAGP4XohVtrKQAbyUW+0KFKtrWxzaVJfHxyAlDthZhzF7VRh21Yj7KCVFRo3UiFhJt5LtX9tBVMsHUlYKHRyxv\\\\\\\\\\\\\\\/tQdZHUAux6HjllCKL0bWr8bCblxnAsUU8LgBncXK23nNxYEvtZCu4maVytBPD0AxJUY+PkCxCQL7epQA\\\\\\\\\\\\\\\/b22Z9\\\\\\\\\\\\\\\/rr8D90JWQPugep7n5bYvbc6qLipnxUM\\\\\\\\\\\\\\\/y5JxbQKWmb8XbzlA\\\\\\\\\\\\\\\/hc7ibnZunqQ2anWQ71T0subZSHw3sy7F+XsHIteypjoQ3EL3qP401TyZ6p\\\\\\\\\\\\\\\/U0odXB+3D7VShvFQ2ITwIvHK7y+bbiADnD7G4HKve0aO\\\\\\\\\\\\\\\/pISanbnK31IK3IUoClaWRssu0RJyE7etbzWoKexwoL8UrJ984o89f11IenPYe4n+SrgKvuz5YRYqPlL20O9frQiLNLvkCBbLP5i6g6jyZOxm4NDaYA8KhmXrewP2e34nzMh7u6h8YyyA6mLLEaT433xrgP8MwvyBpsaLP4hlnfD0R36cArS93xhfQXfiXq4O8lXyrp3\\\\\\\\\\\\\\\/GQYfYtNeSPC9EDvBKiyCdlmAfmvArqanEA+FA7dGwEqrFV+Ub\\\\\\\\\\\\\\\/5SmVbvpZuOwbinRCdPNC2q2is2xXSOXpOwwMrp4MVlWJ4KEX+NKpcPvdBfj121rHIgIbMu\\\\\\\\\\\\\\\/UK6BZyZLqu42pQHmxtl0IGwfRiYpRbH987ODuxA\\\\\\\\\\\\\\\/b6VP33tnL48a9FnxrP\\\\\\\\\\\\\\\/QTWVgctKNYK2LK+\\\\\\\\\\\\\\\/MVl7kN4q63IRvuyjkxr7F26QS7k0KCmT5qAIMYd+\\\\\\\\\\\\\\\/lxAciHGMliO3nLiY\\\\\\\\\\\\\\\/MFGjRAdtRvF6ws5thkRaD2RUXk\\\\\\\\\\\\\\\/4xT8LWLbVx7Qk5ge349NNj3++qd+TSMf7Ja8wVcE1S+A9WIpoxQjk3YXj9U7+rplnqyH8\\\\\\\\\\\\\\\/prdlYXw+jGgLVxPkh3YeJpona\\\\\\\\\\\\\\\/vVEsxiA4vDCJh1Ow5MzwHFZ01N4zxWgXHWC+1Fz6zcGju1UM0ZCSQhzUOtPF4okcvZjsUgiVtaP75LYbkYanz+Z7grB46ITfHrUjy3Ja6mSFPjhW+BrxLKnig2GAaE1CBtD0aiMkTVUlxsfGCVLJMCkmw3ptfCKZFOlALL\\\\\\\\\\\\\\\/AiDmgcGXfZiGOX5dLcYEWpbn3ELmqdzoydSiA\\\\\\\\\\\\\\\/vXaa8FQbzKfvW4iodo4CglicKiGDqijwnwHjF3S7GIKp24tPBCCFnHdj5zqi6oPEiRuhh5sw0IH2DvqGoaOEahZLIz0GNOAhjhU7CGx6cA\\\\\\\\\\\\\\\/hSk4CTddMg=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022WvaOH01SnW6UnfSwrkepTw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c6523c567c0a75f25f855e1531d855f2d9fe607e625a0e1744468ac6cf742da8\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A353.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A353.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0590\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0590\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0590\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}