{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022IC8rDf6kIbTDESgPDPpqcV\\\\\\\\\\\\\\\/qM+sFBQqyEW0jRCX1rFu\\\\\\\\\\\\\\\/kEvQXx2e4phhKv44q9gBRiVACyS7b2xNR0c0YIgoHKgSKI3xW+nHIbS7aBveCc9tMx2QoZ8hIxuMTyitK3lk5JeYApF5HOA+JsdxiTSmGpf5ZQsVcWanBzQnOoEBCTCiRW2Vx5qitQYb13DcneLocmTO3AL9nfnn\\\\\\\\\\\\\\\/jVKXDyCfsq0332DacAFmatA8nLSI9LyNRYxG4pMjc\\\\\\\\\\\\\\\/uIAp4HHsQSQucafVx1yvFoZM1xRYQiL4NzlSzzjnHSATIhAkFIWetbAFoefH33Py51KsVwzAjB7xzKjDLpOHG4VhB5RBac5MptoS0B6WYoErc14o40ZjdCB3GktxzhqrTwEJkG\\\\\\\\\\\\\\\/Wj5PUtm2Jlz8jz6x8CD0YqdSEcME9W6tfymGIAig\\\\\\\\\\\\\\\/DggI2SfMl5\\\\\\\\\\\\\\\/wlf+MqxVJfEtuLp+qBICvvJ6Ghq7aaaTDV7Dmto6rbok4PoKKXSNLh5zdGKYP+iZ5S0O8TqOTg28mAEA9B2I+aEfE926nG2KJKS7ewi6AO5o4yYkMJOV4OZs83B8TnREvJZ8giBvVAl1W78RsJFpid2R8Ag5eZMvuFlZQWJcbDlG\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/X+qynv622Q0lODeeU7Riyip0EkEP138Qwv7ESOT\\\\\\\\\\\\\\\/NMY+ySiRjlsPTExmx+4gk0DKbheID+XWZGxbcsqq8NyH\\\\\\\\\\\\\\\/dA0j\\\\\\\\\\\\\\\/aPNNviFG9oC5ns\\\\\\\\\\\\\\\/HAtrjajVaOJklODExIPYLQlO1e2gYCmE6DpFunYttz3AyEqRK+vUuJFX11vuv7g\\\\\\\\\\\\\\\/8ZDSwATdtHIbP113ey9t5gJb1kDtpGZ5K4sLdtqKovgdDup+2owNbLcM9KkMACjzqELNg0E9cox\\\\\\\\\\\\\\\/MbEl87N\\\\\\\\\\\\\\\/7DtKvVZ9gMdE116dd9drK\\\\\\\\\\\\\\\/zP+3eHC4Z0SBAO+O4Eyds1QTA9Py+7j8y+NtiuAr5fKNJXJVnn0B5UMuayUdK1G1lVibHlwOso61XI71xxjrh9bA8OxPRDQvwBRtqImIDmNk1EJBIReQ60CCl3moVi4ii8bpOfxPNMbsqoGAY67ENjNAqTy0E3CFvcatl\\\\\\\\\\\\\\\/ynXun2yvLNaPXT29ltDHJG9+SkfhuAiCp\\\\\\\\\\\\\\\/i9gBWeMcRf9xOEKiEsPGAWdoqKNLLlU6Hh8D1Tyol85gtltEKQP1ZQVIddyZJWu73iDFY2rC3m5jKgek3D4dMfF9CMlguaa1joXttE2A4Qyjn14LZhTta8OaJMV\\\\\\\\\\\\\\\/6kzTPPCXN+MGtR2FXyq0n3zbF+JT7a7DBtB5Z+FUhp5vYzZS0M412sBiQ3G6ni+Kl0X0wDsccgR3hpXaR8khj\\\\\\\\\\\\\\\/VZy1iYkN1rB9IQeTN0osjwanVV3GRo+O0HnP6tXNSvwEuMsFq\\\\\\\\\\\\\\\/BXlJVbI\\\\\\\\\\\\\\\/kBU7h\\\\\\\\\\\\\\\/m7FTA6PzHrj6d8f0NM3mzZKtUxYKG7\\\\\\\\\\\\\\\/9GRWNhaVGOmRhoTHVkZyhQAqNFB4POZ9msnkI6R\\\\\\\\\\\\\\\/j7FMUrdCggrJZe\\\\\\\\\\\\\\\/usVDrHzsH\\\\\\\\\\\\\\\/peVVg5DOY0\\\\\\\\\\\\\\\/yc\\\\\\\\\\\\\\\/VIePPxeGv23Df980Fzy5PjulRU8yPpIIKIAVmBnJ\\\\\\\\\\\\\\\/2rv40BM82XQpym\\\\\\\\\\\\\\\/kuuV38coHp3oacI8tFOjZjz3B5Ytqtpc6Nfc+r94cdWKMheizYp+61jWDsHyy9BvYiXNTkB71LLeVuVe9fgL3VNvks6P2iUg4FV4wW5gyeqxLlRbGU39qAtYhX2TU5cZhzm7ClP5S2RcaRqhwjwY4f7TdtNfUgAGsfJpu5Qz9c9lL9AUhjsmlZwY6tCZGusLWesH1r9jxsGPOVyl7KpxPz\\\\\\\\\\\\\\\/FjC0IcOZm7we+5LrdWWJe1MBPPXtxblemwBcjH7dLBL7uJ97IxlbkzSAWX4g60KRErzrUkvYOutrHySq2uLOSP6xop4ATMK\\\\\\\\\\\\\\\/jDancjt\\\\\\\\\\\\\\\/DDYSGMQYqwxOz\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/8yxlf7iaiiDkQ4vXKoyfCJVJvySIth2ql\\\\\\\\\\\\\\\/O8WnLvaOqlszEsPJ5gkHPLMwUxlztHHe5+qq08n\\\\\\\\\\\\\\\/jnwzYhG9445o+y5UlyWrDNwV1xcOjCm295Hu7E+09f2m\\\\\\\\\\\\\\\/POKKmIt7Sub76BWHLVU\\\\\\\\\\\\\\\/g4NhRsykiOM\\\\\\\\\\\\\\\/Wq48GFJlvNcMbFTSGFkwIAerHVxSELALmwz11XNKL8YXEx3k9n76E+Hp0c0cMt30kejM6jNqmE9wgvz1C03ivAveWtIAvAUBgf7TgKw7UwMT78\\\\\\\\\\\\\\\/6lK++XK2XaITJoYXKoJo+beuofH2G3meDSXOStsKNnGsj4fSPf3e9Jf7fmnWCfNNwmXyWDRCJpVVRo7k5R1iCMrQcTYy85Q7q3LisbpKushoTt9p5u8HNEh9ae4F3gmAx5mi1axJtRHpwN3t89QdD5KB+k1ci3Tr7YjLVtPp5aIchcd9djp18dICYFwE017JmkUCuXAIjux7eluyWS7rD413yDemi3LkqBXKzZk27X4hf\\\\\\\\\\\\\\\/7iNk6hhsPHwuR2EdQvp8RN5P++m7FUhGQsbGT44+eL3YiDTce0TChuF3Nq2l77wMIHzrVbZXwJRI97u4t4VHpmj4fx64OTtwcG1BNNemMOY26FTE7rveBZAheCLg43KxzjagrxGigerdMeFdFx8Niba70pelDXIIMUSfG3kLPbSZO8nLdR3TuKr5CjONrM9viXP\\\\\\\\\\\\\\\/PrzX24uC4Vf04erkzCqBl5mZsr3hxdtIGUFxnUnE\\\\\\\\\\\\\\\/uJJ3aoVYo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00224HHkzGbTVJlFHYVdVdtVsg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002237a8503148c9594be47f0d795cbaf860a8553fb8a002fa3123ecec45b5b4443e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000943.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000943.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000943\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000943\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000943\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}