{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gqMsSXKjDXPAMxfumezAC5mpfd24+UdKz4KrWhn9jECxVzLq7pjzSbaE3bA6dzHv7qzHHPLCzKTGNfzkeTnCOlwxgPpGaqpVuhBP3HDprH48NMpiwHvi1rSNsweuhv3revOQV1GwxO0W2s27gobYRkkbDaBuNTThVNclD3fWiYB7H5skOzxOAKpacvoLVVknHtSH2xMvvOL0bXjTVDWuFUxNxxLwiXn4vRX+ZWXK5WZq63P6uQ+8bIlYZ9HgyEECIGz6bSlie+l9fo24zaes7ej0YOtnY2hAJPoXInRbunkWIGN+zZrzXUYIb0Dkuu73oiatneS\\\\\\\\\\\\\\\/uihALBW1WO8KeHrfu85AUNDw9bdM1tvmFFOSoBv0S2FRN\\\\\\\\\\\\\\\/BSSDCP5\\\\\\\\\\\\\\\/hVWXFGGJ4lhe4WB13ErmDR5R8KYef46JLsj0lhdMkW8I\\\\\\\\\\\\\\\/HkxaR\\\\\\\\\\\\\\\/wB7JRgedIbGv3BRfqDmJ36ObNAa136\\\\\\\\\\\\\\\/g9XZgnO73GzJ9WBVp9oIrzm50wtoAgv4OxxYjYDTRDS3A2opJD0jmbtH3pnwEQb21QYZlN0tTqj\\\\\\\\\\\\\\\/uTGbQIPrYN4m4XbA3biYw7Eh0346mdKWaiPNNQC\\\\\\\\\\\\\\\/1vHHVB9dbRnr5aV1w5y8YvpiDh0fhPwDwhpM24TJYwDdh+zmSZOJj8X8bvKqlUattZusRVUAKOVuUW10DWSArSR4MxAQnb0e0ebaYSqzNWCY02HSaM6cc47jJh0Qj9IEw6XaHdjoqATw3wFHH08uaPghyaa+8EcokS8tZgubyGpD6875981\\\\\\\\\\\\\\\/+pJ5Scw83Y7KY9ZPs4IcGomS3axCMkA8LzeCgJ2bJzMv5WOn59V5gRTHLkiKgGO8EJdo7wSmGWcOGVNBPf1imbgf9fe57vVAR+aGjyPDtX5FWHD9KGYxBu\\\\\\\\\\\\\\\/V9NhOig+1JyPXXPwvXjxs3Pz+TTo2t\\\\\\\\\\\\\\\/xANNFc\\\\\\\\\\\\\\\/9qv7MGoVg8LXhnhdxAj2POiwiZjCnsV2CvebrPgDKnRg10wBm+d+NgMwtmYbfGPY8ftbqzsYLwoaolzPAy1EiADdj4rfgRyWoREP4RGdjmZrIsFwV3XYCNjyOWuLOkQFzuYepP+7PN+PKIoNmenf6LBRifCTPrNBAUQlcOynIqulL5Qnv4uWWZdJt1Tyf\\\\\\\\\\\\\\\/5KNtfDr1Wr4Wpp82xoo61zWd5blOs2\\\\\\\\\\\\\\\/7fm8kzMrwAxnILSvaTojKHL6qC3JvGoLSkcbeMEfPBCmCZW7g4dM7yFkD+KAgQCLOI0IHnRe4V5amRrbsORaqd0UKXFr22uqG919yzVgi2NPytgDT2eoSNU+sMiyrMrZ7QnOBMe7ux9ud2kKHc8T1aU7MI7tGCLhIcn0TndPAnlIItffmKXhhSSSdDBLNldyYKE7ezsT2AKYQvAc1uECCS\\\\\\\\\\\\\\\/uInTvfunnLqDy8cnQdxmRd33gk0U5x0sUEyRA4yfimJK1m4v\\\\\\\\\\\\\\\/nHxnJ1eU3vc2mUUIrT+DxefcSz89dXB\\\\\\\\\\\\\\\/iPDmbq\\\\\\\\\\\\\\\/9XLhR3HZlnRpGmcGSbWKr\\\\\\\\\\\\\\\/KSxEgTVg\\\\\\\\\\\\\\\/NnE4NVjLWX+I2rWk1VynxLrijcNfFeoWmoL8XqcKYY45qiRSDxrjiWAKIMReFcpKgX\\\\\\\\\\\\\\\/1Z9SswBq6feDy0HUo8KJVFeYWRv1GGajseWW6nJgaAGE\\\\\\\\\\\\\\\/z47yNL8s+HrTo8Gd5x+wg+KPoQLOpwvL6Cf8O4oP2ZfqcPEqHBiYJG9vK\\\\\\\\\\\\\\\/VVIvnriTQPto0tbuwPquM71gpgf0\\\\\\\\\\\\\\\/txMHeqKMOYqqUFLnEjOKTip822asYvLz4i9vkE4oaFAGe5zxWUUn6Cy0bIIDhzlGr+JHMsWkJ2yHLWhfFG7587rSyWAczF92VfFB9YsEzLUwONo1u17j9gfMfCpQ4Gvj4LAG\\\\\\\\\\\\\\\/JUgQNiFsH7NvnuE2g2budTvsfG9iSLG7\\\\\\\\\\\\\\\/9Qu7fnn\\\\\\\\\\\\\\\/rTtqHnaZwZ4bnW8w3kHRN5gSsNjzA2qTxeGac+RbmqFr3h8e3ear4jQana\\\\\\\\\\\\\\\/pxs+tMVVI\\\\\\\\\\\\\\\/bD0EHshSGNcb3\\\\\\\\\\\\\\\/LeS5AQl2qSj0lFRbiHmMr4qA+wt6jqWW834eUIIxCxUJbKf+fvaMAAtDTtwe3ODUK6lU776BR\\\\\\\\\\\\\\\/H\\\\\\\\\\\\\\\/bM4TsOZLUj\\\\\\\\\\\\\\\/Q\\\\\\\\\\\\\\\/KBkP4pZuFcTTHU4rvulGP49ecV6Ai6Hjj9AOz7KxNPTPvcxbTTHvr9gKeLlDVzwMdH7Pg\\\\\\\\\\\\\\\/lmpdUyjqRvnapH9LyuF93lW+F5YohSIfHnkz0YLCp9t6xp3V3FkhaNZuThU9j6XKNLMGK7oAABiPsR8XMi0\\\\\\\\\\\\\\\/QO+lIIWydPelTqsxxOrCsnHlY1F\\\\\\\\\\\\\\\/ZMbBxgfn+UvtAFs1Vm9n1FZiFgvZERDKq8rRSUM9QQCWqq5g0SgEkeG0+ogPT9+9\\\\\\\\\\\\\\\/IINMDyXsG\\\\\\\\\\\\\\\/VlYBX63UfkHofcXSyzRW5By3vCar2zhGKQiZj75R4xjtbKKKg6sYilDVOpMJN8J5Nl8zBwsNZtGJjeZkMmJmaQJggDEvs1UWzuhNTNsUAcWODCKBTNi347bKIhp8SbnWA6+EgRmNI2K9LRKi65V5bECSQUahIjKwExrRi7caJiksrYCkz+DNsdwpDajUnSJ+J8qRlnd7mq+lQa4Zf8ExaAVpV8xUk7LsiPDCsZw4Ju0SK2KsMir5uW0bxEyMtlW8eDEOvdJKbWgDgrw2BSkEVX5vmPm6j04KgudIxzrciHJy4JZ5LaqvqR4DAD5vcdK7LhRe9Xn9o=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022E6yenl2bFk9y+9K3cFceyA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022abbc0789ad577f9ae514b1fac1788ee38b6e38a164e1294b39529eb76cef13c3\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e001164.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e001164.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001164\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001164\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001164\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}