{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022e80jp\\\\\\\\\\\\\\\/apzdPaUG+CuYmOJXiNotcGwsq8p9rfJdOKfyHOtXvXSDrshfsm4U9+Qwh\\\\\\\\\\\\\\\/9XtoMwXLiOntQm9BlsXUxdA5lMS9Mjld2oRaYDcTX7NH\\\\\\\\\\\\\\\/brFLRKhCw2BteXKNQK0xsDGjF0U0ONQ3VX3p+c43aJEMSaoQtx\\\\\\\\\\\\\\\/ccXHccYEUNVFK+oXah2ZUP2mg9LMJI8EAXweKkm6dwuER8DdPWoDnq9l5DadGfFILFB4EdmwilPkWYGSR2UaleLYWhtu45ZyUoPwI4ByWBOy9gC+a0JgEcPXI3JYTiq\\\\\\\\\\\\\\\/+JYyu3ovlTC2Ff1yyMng0FVd+criRwyzWjjFUFCz+iNujs2whBUntF48KYklQoJijRIkDVZAbuAoERtxtFz8S7SWvHpcGadjkt83aK5woT3Kvu4EJOE0Pegk8UsLJv9DEvEj8QXknBdDPYoNTO\\\\\\\\\\\\\\\/BGYrdmaFlI9MEEgq4+CuM\\\\\\\\\\\\\\\/ITQvjmBytXE27q9FKnDGbXqZeOw9KXV\\\\\\\\\\\\\\\/inmKX0I+8RPesz6hZiWzv7nHMcmvXU9Y+SL\\\\\\\\\\\\\\\/Cikf2bDmvn076N+\\\\\\\\\\\\\\\/UBnqnmhHsqdUwwq2KXdfW8MR6K6wq7WMErdaWmlrRhC4fgeITSZeOlwsigLSGBEngXnu5Hx2DGuEYAvnYQyOrKZ5OWk2h0HPCNOqzyIKGW2\\\\\\\\\\\\\\\/GB5Ob1etfEYgT7xSnFgswWKle+EnIGpUT8l\\\\\\\\\\\\\\\/eSfF4KSeLJ1NgDZH1Oe0C9SepimuvBkUDBmhRBZVRObdLAAX0CHuRYQ3UKk1nH92Ki\\\\\\\\\\\\\\\/I0RN2IaqrIuJ8hlTgBFUMdAk6+P67DAiZ2YMjfFX9voByChVYDkPZP570uksHiMfVG7x+IXMNBglBV2PTLtSPUY6u\\\\\\\\\\\\\\\/F9OADXKqs\\\\\\\\\\\\\\\/9RpidUETAXKjUaH0uYUu53BHJr\\\\\\\\\\\\\\\/Ue8AlinwB9q+mZqQqO29d\\\\\\\\\\\\\\\/LPblyW\\\\\\\\\\\\\\\/WWg1N0TPWCzKwJql94T573I1gPsaHvee9XyuNh9t2RDQ9B2BxxujD7CuwuJrtcCEo3UTXEtTm8SpgiZTqoSWY+AGcJVCm4u+dKV3rpcsWwpHkni3v5g0E6ja3lVQJWLU2flx5w2KyJuhOW0P47jyKpwQW52pJqWM0FBVIL\\\\\\\\\\\\\\\/X7mTklm8A7eU044Ou3wjWZkc2tL6pUCOuLA8ejwXt0P5Nyymm6nWt34VUg+IH6u3LnsKnp3pDjUfGr+VrSuTfGwZniHOcLIqDVDZuqk0y\\\\\\\\\\\\\\\/L\\\\\\\\\\\\\\\/1tToBDP5kj54wqcEVRWJ7otXuYyIM05TeJ67nMsWSsCw\\\\\\\\\\\\\\\/okyT\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/2\\\\\\\\\\\\\\\/t0ktWPgF3cuXM+8BDcw2GZ4nhpasadKvFs8rQGmrQYTWbSmoD60uXLU52b7ABBMPyxcgMeKZ4j+wCmhKaglEyJx9BYhwimEKWczFVwGAyfBCVk6MUwO7Y0wJrZzllM1KUlnp+g\\\\\\\\\\\\\\\/6n+ukHLlIsY9XMgeoutdHmFt5W9fIO+GIihKYmlEu8IZjvLHc9Od\\\\\\\\\\\\\\\/u5lCB3EPrJmK\\\\\\\\\\\\\\\/vEVomihHj2uwZXyPWkLV8eTvL7ewD51GhABtPVDQ+PVth3dC+XjF3Sim0iyj+rqn+Z8L8Af26tyto65l1d1v5BDxOcz\\\\\\\\\\\\\\\/wAXgBeQLKmCSyOTXCGDbWlFATT+3puXwIgyr5dEVQ6hhp62KXK4K03xBaLk2Guj76\\\\\\\\\\\\\\\/PWjHphslmUU97MM8Lx2E1Ga0djfusvdE1IM12x6zTX8VpvuNvRBlWXwQV0t+fLPUH0AYuRo29bb4pxTZLFAbz0jN35jtXYndGkcrmH0\\\\\\\\\\\\\\\/M0GPrxdBKEjdU\\\\\\\\\\\\\\\/cLM8hSD6T5YHUflPiZBNwTh5DaIfx2V4\\\\\\\\\\\\\\\/49434NzZNpak8zDTILnRFrE0rSjzZ\\\\\\\\\\\\\\\/Xop6h5Ykz\\\\\\\\\\\\\\\/qMO8jS8sMcPswBopzBsnRNJtoNK9vl0xoYXiRu1ZhuqXVx5rV\\\\\\\\\\\\\\\/jojUVWGtqTssK9KyCr6Z6+D4cySsi1fsBp3R2S+AJS7f3EAZKrNShuFiuoNwPT+KwDqAMlrtgAxX6cRUN0SZWlYZOdiZoiguHpIUyLWCmsfhBDUhj6j95xWW8PqH2LW0uSbbUm+DAkuu9ZrKoZA3EuB13l\\\\\\\\\\\\\\\/U5Bui6kFwgNNL3lOdsLMCg0lpYzTftF\\\\\\\\\\\\\\\/6BkV9HLjj\\\\\\\\\\\\\\\/gIfPk18G4vXRkgqlS2hg0njU6fNkVHxKOfhGclLR6BlCQEzdmAt5pi1IElQQWszUyfrLCx\\\\\\\\\\\\\\\/4PxiLnQCVOV3boTXADAwQtsW43lMbYgt048WptfTIw461lAcl+7JzcZ4F8Eg\\\\\\\\\\\\\\\/V3Lvgit8LjessAFnDPhhKLuUrryvX1JlmLXMUr\\\\\\\\\\\\\\\/Z4dVgktxRlgjRPgORMSx0\\\\\\\\\\\\\\\/7mn65ILv+jtSSvvwA5I+iTGCf2bBEsJ0RmnVG2b12Xb44TehpQl+uuaStYVg0YFpQWK7i1ECanhlQcJItCYwJL6TdsDweCmfiEB4ApkaGk7hPVQsFeV8f6iDzjh9Rie1ikG2FYZ0DtZE8sCBIorTNQPhnNNf7OZ\\\\\\\\\\\\\\\/i2Br8h9Rmhzsy9P3GZhYIO\\\\\\\\\\\\\\\/xBvNDThevzkZbikZ84yquRx3GtR7njGlQNeqXO+mpXkSIIQrHViuII15uRsTmE5Bjggk555xLY4ab6eBoEQA2Yew9V8IpyNl369RowF4EcEVIbCD37s\\\\\\\\\\\\\\\/Ii5bgJ3LQ9WjOCzc5jHsUpHgyi3+Yzjr5TtXfwLDteQ5BR8UpujSOQZgFNSolLpHWj1mimnDJAAv3A=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022+VE\\\\\\\\\\\\\\\/2CjD\\\\\\\\\\\\\\\/JB5AMFzoKNdJg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00222a44ee9e14de929368cc3698fcac671ee0c64b0c07784cc3048a44db6bef2f7c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000406.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000406.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2019-000406\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2019-000406\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2019-000406\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}