{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022r6dpzs+GyRUdhVc6\\\\\\\\\\\\\\\/VEbaVYgMey4pSKbxtbs+QGLMCPnAeKzxvFC448VDzjPzNTbSW5S83p3FTuQmkxnyNL8ctw95Fls1QQtIdiEgLUTK2G7F8Q5zGguxvfubgRhPbHeKJ94kQOJ9nf96sCfonmxzegt95vg0a6w1hpPfdPp77AqZzngJn96k2xLOKmhlnL6jj\\\\\\\\\\\\\\\/E+PEWn2c+F8MaAtrwDFTzN6+c9QpYK9furIP5n2SI\\\\\\\\\\\\\\\/bV4LM1VNncUngDtZXi\\\\\\\\\\\\\\\/cqehKlMN2CmzIQHOiqGYODOAhEdeoVlpThCKPb5aUP6gZQqkuY0O7XgjuExNfggcCxHE4\\\\\\\\\\\\\\\/jTfg6NF\\\\\\\\\\\\\\\/B7fvgVht48OAMgdrYnvopmpK4\\\\\\\\\\\\\\\/A8DDkjMPGLi4FvAQTbU5BzWA2F5hN9waj1d2GAYlbZxoGRzDP8jF2tftOk+MkdiX\\\\\\\\\\\\\\\/uh7aI7xiHy\\\\\\\\\\\\\\\/eK0xAsK9+jJGnf2EiY4j0\\\\\\\\\\\\\\\/u8esJw3QBqzeoPJi\\\\\\\\\\\\\\\/lB4R\\\\\\\\\\\\\\\/uHWB+v1g1KeN\\\\\\\\\\\\\\\/sWeXnHaJy7W9EsWNmxjzSE9VgADirU6FJ2CDbI3e1lm3DDx9aesNNZLYloW8hL862LcyMaDS0euWeDrNTfb38IFjRvlSYO28OpQXJmqcbnZXHe3P2CwT6FpytZ0IFRBjg94x7JLvJa9ALWVHU8p51PZpebrBwbJoAjrirCa5SXkp7CwJjLb8VVPXqSw6ZX9vofL\\\\\\\\\\\\\\\/Gt3imsSWPKTaFA666tVxxozxIYe+3RJDDAFZpKJSK453er\\\\\\\\\\\\\\\/uoNpU6O+n2SMJ4iPfldtJRRGlTxCoYYhSQijWPJImDozLhpoCI1qyd+2DpV+9HBw25sKgj7+kmHzgEvs8ygmxaHzReVmjcKfzO2lSD8P4M4M+kAUJKmvpG0Hcp+\\\\\\\\\\\\\\\/bhr3HZurYoK\\\\\\\\\\\\\\\/3jX9puFW4MS0MueZqOKj+LC6nNtIhYZdACl\\\\\\\\\\\\\\\/0W5lPJHieATtKcKVPAc4Qj6u0f6PF3Zgqo3FkK17Iuqd2xSufOfJE2Y55rWUus4WSZEXBaLLIbG5MyxXdt9IXDVqDf3uNcNchhT1B9osNls2hZqrZ440eOuDz\\\\\\\\\\\\\\\/ZNX50u5VlkJydra\\\\\\\\\\\\\\\/z\\\\\\\\\\\\\\\/9QGuqrasfDUbv\\\\\\\\\\\\\\\/PEAE2Hn3m77M5qBohe4Nb1cI6NBP0\\\\\\\\\\\\\\\/gQ37ckY\\\\\\\\\\\\\\\/h8F2oMbNEv28iOkyPCdnZkrRKXyrW+mtLj2l+cweMbDfkXpcMi9p1mxAeQUy6WS6uSwiEchrMNsJs+zjb\\\\\\\\\\\\\\\/JOU+KOUJCkXRkx7MRSXLn+ZKZol22urq9v5Rda4RPF2nS4VuSa489iLYVmUCcD+hsnjgFbqCsSjDp9\\\\\\\\\\\\\\\/g7xXs+Mnc8L9x3KVag\\\\\\\\\\\\\\\/Of891b5\\\\\\\\\\\\\\\/b5pTMZVUJph5k\\\\\\\\\\\\\\\/M09viVt12eil\\\\\\\\\\\\\\\/Tl2S48StpFl2dIGqxlW7a\\\\\\\\\\\\\\\/kfZC7ubAKE8HNc+IsC6XmZHpKrJ3xXTOI0lhCYpZI0KnyBKGwaQ3DSV3PWXm7G8RG5H2PjQ01yBjtHM5hfpvNizLyCJSViVv9imPX8WHGuVyhF3fJ1bvbLmYkgwtPDi58OCmh8QLlJU\\\\\\\\\\\\\\\/8FYhwFPIHHyNAfqhkK\\\\\\\\\\\\\\\/g7KFhzt7IVGh1cYua+c9RiAO0YTvSToEfg8J9waEx98Af0r\\\\\\\\\\\\\\\/yB9sqF79YEtwDsQHe3SjCLtQQcguF+Zim66DTBAM9bXrrPpEvDZS6SSLhgBCobjaBa+70v6TcfsV403mPo8jEMZ81vcHOoyuDg7MSjAzrE\\\\\\\\\\\\\\\/HON7Zdc6gEA4Ym08m4iUAp3lI\\\\\\\\\\\\\\\/QrH2iUR3shzs+4rUzSHCk2VAssUzZyWSElAM8\\\\\\\\\\\\\\\/4lboZTSOTG1CMLG56L+cCZYTgrifhCZjqJ2\\\\\\\\\\\\\\\/z2M\\\\\\\\\\\\\\\/z1mt7x9e0PcGLyTX8Qrygl3PRGyIuMLz15FzWf+5d7HhIfqz+hcPhdcdGM+u\\\\\\\\\\\\\\\/mn4AmbkFZ+VkJ3eCIRdzK7JlFTbb4\\\\\\\\\\\\\\\/wsJ4RucomhISPrUNFFPNEA+lDeBl1Xcsfkf4ech0X1\\\\\\\\\\\\\\\/lwDe6uflSJ8YlW8ycywUQjGkgI\\\\\\\\\\\\\\\/hjRtkI2qQ3UFUcB9LqlnDgME0CUtmSoo\\\\\\\\\\\\\\\/11BhFagTxWe3IssZt2Duf4Pq20euY52JRs3v2x7nUduE6TYYXKgGK4qOJc0Xot\\\\\\\\\\\\\\\/zRalNg4\\\\\\\\\\\\\\\/XqBdMO04KVN1dZGynDEgKLLrr41cJSafwHxPApbMxbluGPWteXfdhSKPf+h6c\\\\\\\\\\\\\\\/yLnySA2bg3WqCZbzNvtLyqAmQmzX8nYoQDFOVxBnF+7N7cv+mMTEsGd+IQ4cUOCK6ow1URk2xm1Vtl0\\\\\\\\\\\\\\\/MK2aQSawceW9jELXAGlJl9MzFaxJ5SWkC6toQQq2\\\\\\\\\\\\\\\/qYAir4gf0xK2NnrVo09ngUJ94ejZ2NbYGu9lqUnjdRg7GSDWfoK5ie\\\\\\\\\\\\\\\/oEyLhyIidhr1onmzOdAJXy+nlr1g96Dc66OOfxD2r6DTLWsp5bCax7lI7HZJFBv0ozjmLZgUP2hmMtQjPRMsxC3\\\\\\\\\\\\\\\/3KQUGXlqxzhq2sNUaEmjeGPOfvq8VHqaS5Z3B2CuWrL9HHCwx4HR6p6+VN\\\\\\\\\\\\\\\/Pb5W7LWWOZnsltJ6g6P721YTr7EbplkGe6ipJRO9CilkFdkvHcDL4UNkvbvp4eM0pHI6W9r\\\\\\\\\\\\\\\/qjuHD5bG\\\\\\\\\\\\\\\/UTJ9+sxM6sl6w5FUrrRWzWGsJAWIgOrzSKeUn076cFayS7FIEypXmcToUZjIGhHziS7XF0P4zA7xp4Skm1d1WCtrigRVeMcSYg+faQcHoPHNaV\\\\\\\\\\\\\\\/zZPGsU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022KqRPj8YdrGkRqek12AKv2g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002212e20b6a6cae2a724b33c06fa5d1ea4085812b02445acb5bb27029189e8b67aa\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000860.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000860.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000860\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000860\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000860\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}