{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022OxE++EGbxuQF0yzznxWpkrqd5oVMrN+92iTa04QdfxDYi8WzvhrTzLfZpJ72xjNEhRo3XqdfVXLEcTyobisis7aYhSfobmg6LK2lJQNgUyMljdBD8Kf4wl5LmAmgsDiDmH\\\\\\\\\\\\\\\/1EqQVlUhAF1MzTNsS1a0DQQw+Hm\\\\\\\\\\\\\\\/qf+xWTou\\\\\\\\\\\\\\\/twZx\\\\\\\\\\\\\\\/SbmaeotL0sK7fleDxJXufC99JtUXANfIYjGuHHSxLuv83FHk70qsiJUnHrtvQP7N7xS\\\\\\\\\\\\\\\/rhUeQKso0Vlt8GrgMHeApWDBbvrSm1wlabDAAGeRNMPoKuWo51QpszcpFj4juAulCQgDZRZxkeSrF4Oo73OQc9mfqWscqtsB6SKmyfAoK5QPxJzHBo+0UHcE0kTxUU5xxIBu5X61DEVhmIqeMl0hwvnFg5VlFu4vS7oFwDy3mrQaXDKF+2Ai08H8UqXw\\\\\\\\\\\\\\\/r97zQzlXLumpai18pDmBAOd6opkj7o9oiE0C7x30o+A6JMrtjmFEZmJ\\\\\\\\\\\\\\\/l0dVsI5wJNJir1hBxg7syh0VoB8odhNgNws+IVkUd6KqMoyQtb+f78YxUUaQqb1KvP7StG5QExP5X\\\\\\\\\\\\\\\/kILM256u4n+ZlF1ifcGYqHxUcmBW3FWbRWDB++s\\\\\\\\\\\\\\\/myepWHuTiEj2po+cMnufSnVxorOQFVBzUZTDE6\\\\\\\\\\\\\\\/AG4A+wiww6A48S4Qh9opemxL8b5seq169q7EcCJHEUvrIZDMpHoM7\\\\\\\\\\\\\\\/4iNjc8N0ck\\\\\\\\\\\\\\\/7wAKEgextl06efxyLyMb4SNUYL90KnAC6tb41bCAdsu0GiVv4i6pba99UZYaLbfZwM2Oxns4uCL7Ra00sPek8f9BeWRt6tocTK3cVgZ3mW\\\\\\\\\\\\\\\/By1EmSbgP\\\\\\\\\\\\\\\/VH9gn9mHAP6qi+htgfgAO2W3J+SvOSi+tayTTRfJJagbwj0Mk3vowy06K5JF9XUnOkX5wcKlX23yImWHFLccSa55kGjk9kOZuqbMOqJIOM4IYoBUsKDnuh3CQZPw8NnCSqJJqywF\\\\\\\\\\\\\\\/1fsncOXPt8ARVn823u+r1bYUcV0clmPUQmlSyZyhXz\\\\\\\\\\\\\\\/sH02kDfswlEevIDylLlnVMOWSUHSTiD47jFA6ee5baytxD2vcuQQUi\\\\\\\\\\\\\\\/d3xqR3XFQrb6zc0657G4jbCxpheDqcwqc8DZDZ+59WoQRh47M4IpiXYgdnM2xeq7vrCXUg1pD6bA4aSHqA10BWv\\\\\\\\\\\\\\\/AZ5MPp8skKDI20ZF8PijcruXBVwNpmVMQhAp2nc6zZGeeTUHg7OkESXlBWfkQjYrusDy\\\\\\\\\\\\\\\/Vujlkzg1EfogmL2POVl9oHB1KtpqjMgzkRjiJtmGQ5\\\\\\\\\\\\\\\/qMUwUsh8ghs38aOhoMsE5REdLK5rsxDbY+BIsuipdCN\\\\\\\\\\\\\\\/fMgbSaqTTvIBM2yx7X4msB252yXbL5WzKJJudN\\\\\\\\\\\\\\\/QYwyR+m+DdIXDPd2GwhG6pohgCGdCk25I14QZmp5SrhnwsHUSQS4SjNh0R+wV6xk5R+s1n5nYS\\\\\\\\\\\\\\\/28ND5IpwMZ703lMtkX8NDj9t0UN7ahYs7JDrR\\\\\\\\\\\\\\\/CX7qZNyTLz+CuTHAjvmv\\\\\\\\\\\\\\\/3PhsEIvl6Csto976s+F1OeNP7e3ZP7idrTWqW5HzH5Hm7O0CNogKi3IRrBtGJBiI3ESKUkRDRpkN7UqRD219kKgybAFefdj\\\\\\\\\\\\\\\/BO7pnUtFSPt1\\\\\\\\\\\\\\\/Y9n+py08ExIqvdVX863\\\\\\\\\\\\\\\/7KFzDuTsJW6RgvTvUqwjzr9ZcWwg3VYI0fQ2QRtMlcbVIbfWTV8yalSCa3G86LlOOYlBzoRDtcRjKP4zB2OGrGCXm87cd1hEffs0FEZOT5lskZ9DzPEIR9WpB05Wv7dg2OFpE9d8aRrX8A4Z+ep9nlP9AMDAnkvEREywfrizuJtQUlhPmUllRYRjut8KPcNMPMGRDtujOKzW4dK\\\\\\\\\\\\\\\/PABDGD24lxmGVIEMZYYnuc9Tf2ee7YkYaPVrGxjkfyY+vLTsGYW7B9rHams2Be5plM6HNyRmT9c3gh59L0Bpoa3\\\\\\\\\\\\\\\/K9diAAS0pnQbIuD\\\\\\\\\\\\\\\/VTq\\\\\\\\\\\\\\\/EIngjNy68WtrbTcUQWZ3hefbq6ATx2G4Yyzg70VF1LLM9KoXZCnWM4zUbZ5DiKq0t2SYDnFlwTPmiTyJixnPNVqR9KZT15OU+lZ96EdcKsN62SNBIeo5xGIxUiYN9IdXpSyx2EqSvERtEV7zFgXa7B6NIyPiU3XOQZGsyvir\\\\\\\\\\\\\\\/PFrmfLm1oB5Xhc3IgSVhdc8a0VKQp4DiclDMXU6TlP9QmmeYIwf12ReWjc0XokUOllkfVZ16LcFOGTS9yx\\\\\\\\\\\\\\\/Qre6TtM5DVFlgSU51DkAPy\\\\\\\\\\\\\\\/KXLriFM2bG\\\\\\\\\\\\\\\/njgxU98PModCpP4TyseYDw1xpMERnvMeG05hqx+sL9g4bSPmT6zm4y20b7og6yWAKPyo22n5Qiq1hwRajFRvtC36BRbauYMO1yVidlAsZZ2Y8E0YrgoQUKIh8VSqO9OXzZzCSsMJyO\\\\\\\\\\\\\\\/RGeCiCPnhU\\\\\\\\\\\\\\\/D2GapXkIUAw+36xYnpRIMmmc7zwkp1Uf1VCOmLOpgPCq9VXMwe1s6MhNRyqjQ9WAMg6s3D0ktCcGiHgq8L\\\\\\\\\\\\\\\/VdxjkgUTovIiM\\\\\\\\\\\\\\\/5NVsqB4Z\\\\\\\\\\\\\\\/BlTHmzTUIs0Ke6KJUBe7Z+FL\\\\\\\\\\\\\\\/nXWeDGtg7WHx1qcGbS2FOdt7UPBPqAXID1IIkQxn4zYiTN0K5EsjjUhMKUM8zlVirWqXrgHDe7OgcxwODn59O04O\\\\\\\\\\\\\\\/TQ\\\\\\\\\\\\\\\/KLgc8MDnxVBzxkM+SGrjPU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022+UCpBi6Cu72xIQtYwLL5Mw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00220007bfa975c2f89d3922c7ce356b973b9f6da704940b90358e352160611a8520\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000971.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000971.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000971\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000971\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000971\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}