{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022m9SSGB0HwwJS9MxknwsUGp+3TedTqPXr6VWG6hCKWadRhHfKADvBKUlFBdNByLgj59NIh6zAUn6+4cAGot\\\\\\\\\\\\\\\/t77gZaij+iMoRedfCjRbQNIqm+8+tF8Im+eixCy7tfQON46LU9NgCp1UV+9PEWjT2NmY2\\\\\\\\\\\\\\\/JYgLeDzvs1ecWMS06FKJm6Pk5EEbM9EJ2L739Z\\\\\\\\\\\\\\\/K5sYCtvpYH1pyaJ2lTsUjj8d7SIM9TOGOXF\\\\\\\\\\\\\\\/C0luKSbQxNOWNNyNlK6otWzqp0R5cFCqV1z3qIMpGOGMFhfmf8OKLNiD9IszTbSUiBAJrh62tE2mc0NW0E5W2d9sW9eccm89WnHOQYdlTAjuTZfV9Ho2mKtQtEc98IA6zO7Z7zzVV2mS9oenLJyCEIvGnv8++r2PzaobVfa95J2zi\\\\\\\\\\\\\\\/rkPaGig6bIrsT152pAM31I8nqsItiNzKW5REwIHj5TmCeHvJQuBnqCVp7KT47PsFd2YbiDtLZU0szcFOax5bzBsMl8f2tJAoo9bo9Xr65FHsvK4oGwBB3EewyqAmblj4FJT5NUAqJDvRwt\\\\\\\\\\\\\\\/ioH\\\\\\\\\\\\\\\/s7jwWA3SwkzqFnYfiMUwjZsM7cAVFT7lO\\\\\\\\\\\\\\\/CFsZQJa3vcfR434zptx7RZfx+ijx7mh+DBnByGyxPqTIm62QZzQVeW\\\\\\\\\\\\\\\/IyExluwD+iUOASIxjZ3WSs4yNXw1y6hLOZkYsIhkwhKaLYj7qDA8j1uYk5\\\\\\\\\\\\\\\/mI35jCzr\\\\\\\\\\\\\\\/w59itLuFy7GavUWCXK7gIP0nLU8E7BfK+d8UbWmy7VAbXwHFbBsBmKeoCIA6MMTJhIXtr4D\\\\\\\\\\\\\\\/JkYkcOnoaH6dgkkYrXR7VbTd9HMyb56zZE0Uqp1qRM7NL3tZ+1drlcXOFEddjmF1GK\\\\\\\\\\\\\\\/DGRFbSxhc3e51N709Z6wbgKkbFrfHe\\\\\\\\\\\\\\\/FFF0ATjNnY99qTb5yrBGJxJ\\\\\\\\\\\\\\\/oj9fcqd1F99ReDU9t1SCwb0Ix6K87VBkvBE5urcdb2JxJ7uqUH1vDxw7tfIj0u5ZI3ZxbfLA9SrMNRKJZvoAIMWiHPKaOh38cKTEgzD0QWH7n+eeZlTzniIc1pPSceQPpjettWa0BAVU4KXH\\\\\\\\\\\\\\\/obH09cwwczohU1AeRrNVzq2Cex2ofz+tlNN7AIrgDvINfg11XQkkkyLhg5e+ZM1vi1zRw9xR\\\\\\\\\\\\\\\/cYdHhCJqeaIOY0de5XsFoJkugVV7r9fja10mn1PEEMZx0DDMmhfZwCan0eeNYTgQ78zwyE9gG78kWOmD11uXzXMsagRDD4vWlOPgGnhEz67dZ3Y7VDjoloZDT79mXXke\\\\\\\\\\\\\\\/Bg1KjdcoNv\\\\\\\\\\\\\\\/5u5Jmang8H19queTDEP7fG2ug\\\\\\\\\\\\\\\/s0i6vPvviJo5LTQrOuiGr59jH40dZxmGr+d6ulB9kxSiPeAm7ofw69Otsm9+ei4RZ0f6iCMjCTYS3wdILLyr0taQYi4lbGEFlz2bcGzYO\\\\\\\\\\\\\\\/VcWEBDnx4y\\\\\\\\\\\\\\\/gwlMX\\\\\\\\\\\\\\\/GS0SEzuSb6rK\\\\\\\\\\\\\\\/O3GLJVqSohvdKJI\\\\\\\\\\\\\\\/ZsbNPceKEEucLTn6upe4ShojtGDIlPzhAi9PgardA6LZy1TJZarC1J+Yv01yOQ6yqo+ZX6DRFK3nQtZdQXGpZdDs0K2eFPx9zXAAhTYwnGXpYcRqhNaEy8FJeBo5jfAkkbi22m5j4XRzrHf45NNlpo294vX6ibe2cUEtESAXjb+D2CAobI1BqqH32KyIKBijpFdRrEC1lHc4c0152+FkpjxABTZ0tZ9dpG7tHAcz62OiFMHgHXLBvxLqsiqVVgDSG8TNwlBDU0OJOCZX6RWK9Ca1qY\\\\\\\\\\\\\\\/ixZyaYyEFZM7U0iD6Kx3BA9S9yGvijJBXrOu5jgkAUUthl6ZrC3G1eCGEcFveLvlKh7YjxqMuvHvuZAckIu8dEtqkYMKOLxy566CI5Cn++90LEdw5w3PTLa0\\\\\\\\\\\\\\\/d8nW\\\\\\\\\\\\\\\/N2GsM0uuYnOsvNmCY+WztNbEncTsTWxETg4BupLkHfkZ3tmbrYHF+ssUAkWm5GEne7NT8cDhbqCQSnB8h0VfxwdxDnMfENlmi9qqPKJQd23w3lbZPa5s+2SWmaPf7ntfkWDTL0kYmoy5qQChlCIGgyOQyk5WzOhHkL8lY8o\\\\\\\\\\\\\\\/u\\\\\\\\\\\\\\\/o6W\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/xjTO2lV8tRCdyz2dvc+gwI08TbweGpf7MnkzHyqdfNivbcGhu1r8bCGKG+mdyc\\\\\\\\\\\\\\\/YQtY15B5EOlDNl5ZF8o0mFUJq+HIvkC\\\\\\\\\\\\\\\/E+vlAZfGWOYSKjynZI\\\\\\\\\\\\\\\/9DnpLMR\\\\\\\\\\\\\\\/5beqS\\\\\\\\\\\\\\\/RoWou4anS3P0mwbOIBVhm7pkx7Vbksj0cHyUvPRe8x5OlzMyEyaJIN8OTfW8a+qnYqbU+NVA93gxpmtKDZuWh3v\\\\\\\\\\\\\\\/7BVTjX0N19fZz\\\\\\\\\\\\\\\/shdiULyo8nMv5V+3yDH\\\\\\\\\\\\\\\/dt2DeVc6xpkL4eyaLahNf5AdtEbEHdM7XRWfzTkxfSm3JOngVS1y\\\\\\\\\\\\\\\/5q09Ur\\\\\\\\\\\\\\\/IxTbNV0ojlFU0yGhCbkO40BpKhehtd18yJXR0yOMuaPZu4XE3fyQRdy\\\\\\\\\\\\\\\/ZdRevlg8ceQapEP\\\\\\\\\\\\\\\/wqi+fhfTlU6MGCqgJYlPUnDxwq8olr9kuamxxJg9Swl9Y2HnZZoP7ddy5Beia4ObT2ZF5d0PliiyPM2B9vlNz3oGQIE3rzPpIGvB7q5TxuRZ4hdzGAFLznx8hl6lwamajB1jqCjlLSzbqUCMDZXpOs8WXpj\\\\\\\\\\\\\\\/hRtgwHfE7ObGv1yVK9QOmsJIMnPkXIAx5PuD5ytK9kcuk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022zuodKU+cLRk3HaJBUx6USg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00224acb9e183252f0c00f2c4550454acf91c52fb5877ea06f9457ad6fccc7e25b8e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e001326.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e001326.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001326\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001326\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001326\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}