{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+T9f77pHXDTleICv9kVVDAeODTjDKwWg6KVlAA3+tRRcE8snBUnAMy8NylMOwEAIz8R9+z1PaAMTxOL7wp2nfg4fVz6FQcY9aqHMPD9ToNBJDAd5bhNAFJiJ+0\\\\\\\\\\\\\\\/FxuwTo4yKBbT50irc6+Dtx+tM6EPeIQlQAqRneMLHiMvuba4Tl7T3fG7SuSQ1VtlAtg\\\\\\\\\\\\\\\/IniB1ah21S6TlrPT6IVSB2NB2xWTzgC01rnX\\\\\\\\\\\\\\\/6q\\\\\\\\\\\\\\\/iyiDYZTaJpELYm6aUBX1K2vQyntuiXZEuRidKS\\\\\\\\\\\\\\\/2p\\\\\\\\\\\\\\\/Vbydc23tSYU2lggV6YqlpCDeDyMImwVwSCRqdHcNq6070mGh8LPLk4bm9UrhXxc9gnuYZQhQolVMWuU\\\\\\\\\\\\\\\/tk4UMHkzlA3QjPWpktXDvsZf6Q9als1ivaZyi6BOJzxY7GE8JS3IHV8Xbt\\\\\\\\\\\\\\\/DhLsX51GLmIIfjDtkm3zAbVVyaYOV4tY7p5ind7Q6MhTbS7qiivgNA1G0xVsV8jIY56RJ\\\\\\\\\\\\\\\/snZUWF9qHh4JS9KEE66O\\\\\\\\\\\\\\\/E961gkAR9eUshoEGyqNZDhTUuWi7HF7a+uxd2E5QvaAuig5MmIhJ1L9iti2dGgws4Rp5TPHmiAt4Uqp6WOi6FxckIulf79i56nr7q9Ydy8yxPPxjhLp377HLFcNEVOM8xEvMxDxJTR45G8XK2ohBBA7PwGtIoNELhTgsb4b10NItRn4UICiMxCTQb81toZ6eN+2kBDYHSzobRLzBfQ3gq9eX+cOpJAUG2fP7DX5jR2YeKDVMcPY3kMhs16HZ1Guyrd9Tj4M4wZZ1HFU\\\\\\\\\\\\\\\/Tw6tJ3Tv\\\\\\\\\\\\\\\/rBX6KnDPgUY4GeCXbO6EukLWn057SBwBsJaIfkqkQF0UgWDwCzsI\\\\\\\\\\\\\\\/QkNdRjvzn22WORzdmJPJOFr+xkJUk3aa+cooavHIf+7Xk6cNebrKhFbkfOzNGCLwSp1z8UVnSrxTrrxc+jlJ7334VkY+NtMQSNpl2L8aqKAuBaEGCGE00oiS3Z+I3i\\\\\\\\\\\\\\\/6Al7wIEjFOlNiRtW9dE2NMSnQjfc1tCe2lrMdpLlWGg85RLsRpfGWaMk9nGPuvtuIz4vGs6RIO8KbF7f9EZYk3H1pW8HUYRbhQqwmnKUxUmtdC5b2satG\\\\\\\\\\\\\\\/mzm5kACdmLiYZ4fup5N23MhpWo1NOdgzvVRlNHOGnwJJeaCSUMW0bWC0roEvhweGVQlSWijzi2CBYWrikl1\\\\\\\\\\\\\\\/e\\\\\\\\\\\\\\\/D+ebTKA+w6SrccT5YiS7pgIdXvAJ8T+q6d4sZ1MQtVFQ+j3PNZOatAXPrvmK\\\\\\\\\\\\\\\/lJJvKwoGZmx9g3xQo9RibbRIFvBJ5ck+jMXGXIJKQIo3A8t3S57awM8E\\\\\\\\\\\\\\\/NZiLz80bu6rzhwXoegwUVY2tdqI5KYSSjRs4yLln8NpTkjq\\\\\\\\\\\\\\\/KiF+mxg1D8HFb9VkWHyayeDQk6l3a3kaxrsrHJ\\\\\\\\\\\\\\\/W848udCROyNC+aF247WR20HC64SXF\\\\\\\\\\\\\\\/nRRr+IbP5TAbr\\\\\\\\\\\\\\\/I0tjSZkYYSK1kvZpVnypEOhOZXD78DWTSGkPuy+5wbvOoINH8cSDgGyaTyak3DV7\\\\\\\\\\\\\\\/5VRwwmHI9eVc9qN3bgqLNDRW3bBRQYkwiqyvfeCJR+8tWS7C8hckK0pkR+1Tivgi9hUHZZoyd34p8lgcrp2wV\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/R9czwOT473RP0Jl8rOyH\\\\\\\\\\\\\\\/PhKMXdsdHQBNu7LLWJy28dhKHcmu7PExC5I9xj5j9WdZLoyncuScLijp1u+4Yrfef4v21va8+fH\\\\\\\\\\\\\\\/awbNtllNlF+8VogGv8wr8dCI0Ey9x\\\\\\\\\\\\\\\/EULyan49dEcbrpYY7eYfUiZyy09U06PpJpJhEgd9yETASiH0IruBoW0K10U3ehlbpHmL9QRtHgFeolm1yiKLX29U62VxZloLFkfTLbKQi27iPJW9B\\\\\\\\\\\\\\\/hsaOb6LBrLoEgM2Fe751NLJYX9C4GsychXvd\\\\\\\\\\\\\\\/9M1wgTo6Oqij9Bs9pgKw5vAigpPtCamALydCRRAViUXD7Q9xAH9JoPOFTGQhs4dEXbyz28Pftn0QuygRdz\\\\\\\\\\\\\\\/Kk2JQu5ei4tllS1ieps98mkYM343ddxvQu2TJzqQb6PnQLcEOBMLCW9c+aNLb\\\\\\\\\\\\\\\/JHiwMCxBBWjbM2yp0ZvjMzC437ftrOwCXzyosuQLkpiGEoYocdd0SXg004OIpqufVQQqib9jrihAYAgGb3AokCsONHRxEEsy8F2yr3Sclxo2cE1C6hDESPbPzdXm2rrP57UxtKKVjzMPM8JLcmVnBf2OMiTIUBZAwRv3shx8qZrkpWghpLT4UY\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/BEcIhuCW1bDxWNmYq\\\\\\\\\\\\\\\/qd0dim9T7AhSG3W6IsZh7xaLN3f\\\\\\\\\\\\\\\/3r2VRAQajebnFLBjLx5cgwkaZqOmpeuF41ymiaFvUbSJXzziHvd01e1d5sZJ\\\\\\\\\\\\\\\/F6yilSboZuy6JtAaQBTrp03Rt+1zlR3uc6p8rnzIOWsk95LUPqQYuFvtZb7LzYgzBDu7zfF2WIem1rqffJmG0znTNT2bvxF6kz42nGlIdCzljYr+1WKDTm427z0OVmKFoV7DqSFBjz81R1vaIaW5\\\\\\\\\\\\\\\/KZxFGPiMixRmOJCbKaIGNy9CKDa+fZbWJlUa0rPoGBQ5ByUc4jWZD\\\\\\\\\\\\\\\/2mmepy++2L8uqB7uHFij\\\\\\\\\\\\\\\/ZVDsgymRm\\\\\\\\\\\\\\\/atxwOUdNMsEjbUnt0UJhFHh272MXei2uqiybVATdXOKtmh4tbW6zp+YiaynPItjnQtD0J4eU4pn1eeSgIMdzk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022IjkZoTw8xbZl5a7L+Bgb\\\\\\\\\\\\\\\/A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022e62efc4253275bc82424f4a791f6a9e0a4d8834a9c0672bb30d0864b08ad21c1\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e001155.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e001155.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001155\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001155\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001155\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}