{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gaNn5W\\\\\\\\\\\\\\\/sWOGX4SypRUa9CxFAJLlVBwSQBidyaLP\\\\\\\\\\\\\\\/EY4iPFbioZy1vR3TsiBF8vGPxU4tvNc\\\\\\\\\\\\\\\/FGTcPfxwPPEMC9AagVOS+xgrGMtAmV\\\\\\\\\\\\\\\/C9edEKB3iCEz\\\\\\\\\\\\\\\/Ak6xMGs7uN39LJzLgy98PPYaaXL2F14qY6dC6yBbSDqZnaJhX6CttoDVfzCFFxSL3SFx8FZgY5JkGsziUldo7+qqmEdKjvyUgr+r4dUre4obNLdIsktNOqYfY6jltn2LIZAs0KO3gD+PtYYGH0KWAEZeWZSfc0T9XyM7K\\\\\\\\\\\\\\\/DogHs8wWYmjnJZEAJFjlbwW87rwiP8uPrcvi81UiknzfTaD0\\\\\\\\\\\\\\\/UQo1u+rqxVzOMsBOEh3WVHOwvJz\\\\\\\\\\\\\\\/PZ2fcu09lOm4dOcPxBj3KatRiprVukjdjkXWYq8BCBGKAKykAbhLbK3XmnhaRGp83+3Oo1TJ676Qq7pu8TKr1eZtGZev6L9ZPN9OK\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/as78MAUYBGDVS\\\\\\\\\\\\\\\/Y67hH9K22xS8+rvAPk75M36lYC+2gAWfDEhYHkpD9CMNBx6p4f2DINl6K5nVwGIXML5Qx6p8tTp+xsEh8S27tHBTGHAnIOgrRiGfAZQLP3KK89bH1NuIhl+aaDHaeSiDBOKvPQdgFFZDXwVWCHYJme1Q+84gHqKCTOH6wnZ\\\\\\\\\\\\\\\/d3e5lDtcAp8g5u9vVfOyYfLqMZYrzm0402Wsw4eb69H3Yy4b\\\\\\\\\\\\\\\/To6FDSH9THmAiIiyRuds9yNj6FDjZBz3JJ\\\\\\\\\\\\\\\/518bYueC\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/6WgkxDr746JHYqecLySmkLxhc90KafTp1JyopKQXqQstri6EFmJyBD8QKrFuSnnqq6RuJ32cczBrHTCbHIL50hvq8RjX3055pLnGnQhu0BnxNCmJBPxpByrPP3zLit3xnAedlpfZMv60cyBvX0Ogm6Ub3p5OjB091\\\\\\\\\\\\\\\/4Ghotka6d1DkPEKh1GG\\\\\\\\\\\\\\\/4j6BNMfmBLJymGaXTT1wYtl\\\\\\\\\\\\\\\/CxTTu530Qwlecs0p6SHEk5tAYfGQ8790U6VlrfIX+x5YLX8FhitiIP22NSbYHeUgaG7SAFGQtOgq5JNVpozbT3TkGM32eH8uE4JQMyXGw1bFiY+tS8cEIblSUOSiY5O57tXwtba1xo1tBppPJFRQhsBHVVzXe\\\\\\\\\\\\\\\/ArckbeCz1FabVrQmaGqyXvFFyRZrXGonUEq0waAgyS\\\\\\\\\\\\\\\/JT\\\\\\\\\\\\\\\/TjB0mDHxYMVrukpGXqRIYJ8AqDjrTODJcrECIEHxoL7FkSAeBJ9RPAO2SdVaTKECg1OToiVMtjiCf6qjpin0YsUqvOxrRDTbAJIkL4VX6AhYvitVVFJgwJZg8FwyGsXPScW6kUo9L\\\\\\\\\\\\\\\/yQajfxs2aft\\\\\\\\\\\\\\\/rCOiqGxU2W1jxqpGler4ls+ZumYgxFstcsidM8SpjITcoHOUGGHbq5q1BRRehcO5JV85Wr1qik4Q6p7BBdacKIlYPeA1vAnJkQSGVCg7HTW4eGsZ6herPHLApxPDWh62Wy9CHyf7aoPhuRqHbL3wbXS79630Cx4HvzcP7FrMPCWKdrfO6ImR\\\\\\\\\\\\\\\/8PEvaCPTtb\\\\\\\\\\\\\\\/brrX++CwuNxBCZ25bYsrgmdNpshfQOLf8L\\\\\\\\\\\\\\\/46KBfzVZCYSByS8vWkBcZkNm8n7Esaxrpx7Uqyei19CbT3Y2kbW\\\\\\\\\\\\\\\/xAalfoiuQyUOKAHjrqpK5x+2lmgE9ISu8JGq\\\\\\\\\\\\\\\/33ojE3RYTw3AlT0TX9SQzcUfbG+sbQXrSZKLOgw3MREf9RbfWVWd+5elk\\\\\\\\\\\\\\\/pPCzCninIMtKAJgu2OZATpFfel3f9Pot4hL2Kl34nN\\\\\\\\\\\\\\\/dPH3qIxSG8zsqVOZUh22OwLUul9tQz3IKENIl01QbeolOAxzHLXOSnCXDA0kUCrInnl+YO6BxymzVctbOJleS\\\\\\\\\\\\\\\/3B8j4+0pkjg75e+KFhMjcvAk1kNyWRAWZxf5zkmRDZ8KRiWJ9jw0yr8+17+9xW5qxGkYXzNdrWqBD5v73jJ5uaWI6\\\\\\\\\\\\\\\/JASvW8bogvMxBIb7A0HyxP9YT9XWRkXC5c3ePIftPpIzGhN5J+2U9\\\\\\\\\\\\\\\/ffty3iuPnemKYzqeT9PM4hsh67TAlTR2GixxiGl0hbPbbKAICjYOZ68vzuuk51XqGxNaOhBfMxBCL6IUL9vAESXh74OdoaY09c+nJS2r34IKnP7wWZj7tsZlJ7byjEzL37lTGRFOUhbLnreb8ry9RfXZ\\\\\\\\\\\\\\\/aS74LFydy+2nZgin67tgfep1SWdBYDNvSb720rMtn1Do73mMOmGAbObKQr2Q\\\\\\\\\\\\\\\/PcAZ6Qg55zVFmm+VhL3eOaDmIxlW8IVuey8OtkeG2hnNDuRBeCD4xBUIsUkO0FTwKAs0okF9lrWC+1+Xy1PetE5gWD1CviXwqWB6XoleQfUsW8Tv3HFd3dsIvWAONevoSxtnLbZ8UtzQpN9f8AeinBoPBnnotG4uPHVZI5FzhOHoUopGQtbC8Xy2Do4rsUiE1LlIAlL3t+DdF+sqvpLRAOuJn7WpxySgDkxz6jdXQfOPfrpVr+bJZGHsOEhPGnOjUJc79llZNNJMLGDwVKIHQN8HzVN9H\\\\\\\\\\\\\\\/Qssxo+FmPPguenALkls4f4q\\\\\\\\\\\\\\\/8bB47cYqDPRVs8+dYgka6j5kYjW+bhuvoZfJd9yrUrniIcdpZBhZyzsjNwOEz0yRIULQBeGTlc7gd7hwYpbgO7JXLrBd6p6ncDNqJBd1JvCLXEP1QxQpoxCVifuK0Z7HA6yXz4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00224Le7AEqxkKovpLcwGD6DnA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a93e04f45491f0fc24f9a7b5927a7bf3502aa968d66b1d2d257e1f2c4bfa63d5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000873.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000873.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000873\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000873\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000873\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}