{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00221dAw3TxH3Hb3clQcUL8C7lV6tGFuLWhSuR8eNIwR\\\\\\\\\\\\\\\/QC3+Zro3n8ZEQCYnsB8d2SPxUtKlZgdDLpnMBh2lksz1mFTPX8aYQMjGAFesGl22xqbkT\\\\\\\\\\\\\\\/69XEuXn7dcUXj0IxuhTNAapgFFaFJxRhCU6bBm62vZr3ila7\\\\\\\\\\\\\\\/oDRT42f\\\\\\\\\\\\\\\/Ay\\\\\\\\\\\\\\\/p6ViGR0ym7HUPVfih31+6Aftlf95+xJowY3Q3ketoPzQ8FSaWY5v2+i3hNyByXpRSk19Lne9oGz2bkZWxGo8jfuuGXLcLSdyGvfXK5Vv91ieXUEEpOq8rsCtF8RpiwKH23lXhieK0RtGAyKmZI62c+qrCyfuw2FxqthD9VInHqpG\\\\\\\\\\\\\\\/dMj+tgB6vgNC3RwTxJdA\\\\\\\\\\\\\\\/83E5WvbrjvZWmPaOMyCKACKNSM48ZebczatscRRV69Z1w5CHqLR9ZOrMlp7XqqR3rg6TwmCF650N9Zduqridx5CydX41xn9U+elEsy6RsvyRLmCUkI6pYAprL1gwHo65traHRrJsUBqwunA6TzG6oYqIOkP7oiq3izny5iNl9i19DRCM9KoWIX8vHOm3yptukvX9wx7SB2Uu+w3RkJJa4\\\\\\\\\\\\\\\/LAu9xyYHOuO8hGp17+br+FAO9z3h4332DyqVjXYOHtgdf4N8ecvSttuqxZBEC9LbvyvATEjnQ+zg5ktr65+KGUIghM7of0qheroWg248ShQZ0cHTbHu7JG9xOztpKp4C4iETTApZo8SO3L\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Mb92l5vF8YbLWyQBejv1OBzu4MEWPUHKyrv4LFaDsvKHfBaFtvbDMO+Kdf39N6LmoJXc0mJ6bvkBrdO+Dg2NKDq+49tHxi8DOc07aZjh\\\\\\\\\\\\\\\/JRsMHJGjRWV\\\\\\\\\\\\\\\/Q8DaXaKp+wngucWz+1Gqamjj7K4i2CcKIzb1F2Alrm+I6wTadWELy8J+C0KqXrs3MHnXi+\\\\\\\\\\\\\\\/PaukI6ZYLrhmsd5h8HJLhfaEB+2HXmzj12lgTLaAKbVyPu8cKyCkZ09UYCjOqzFDDjAom1XZs5AKbGqioySVQOpGf+UQYCaEdTWwxt1T8l2H6FeFmDbr3xLeFe5xHR4YrWxtb3uxd2TSPLJkJxjsC3+ArRXp6WI2c9DExXf4XGn2VmTuZUO23qeae4JEOTjsygfCKj7CYIwquts5rNZvkrf8x2wBsmc3yeORgyj2JdtAwdGFK1CcChgRozLadDnsJtuJa2unnWlpI0ysR0yN5Bnt04Lvx+mOftFvilZmtGdM0dAWf64yQv62BMAcybx5xWeHEW\\\\\\\\\\\\\\\/eb\\\\\\\\\\\\\\\/YHKNWZmzkH7ir0goOSCjflCRF7+5K7SDAvNLRoE7khHRoSfm9K9SkWU+b6HdPa\\\\\\\\\\\\\\\/Sh93D5xe7\\\\\\\\\\\\\\\/mKVhCvRMGGJQgxkXfIaN+Q6lYlbUgb592o7Y+IkXhZnmrPR2XbSluyB+yFXRezWkYXB7tyrmVV3AKag\\\\\\\\\\\\\\\/anGB3qWbZG9juQJivCoAKmGE4DkR9ol+mtu8AodHGbCLi+WMdZdVvVAoh+C2fHEJvjogJ9hozHxytLZRefcHa+pwiNthoA1IMwaV1PU0JsPeESscH3u+0rKUH+5AT05aRqoA4qN2rUcO31bctCNYSgQc0dlV4uIqE4a0xH+Ig2vGPzkGUDJwP3r2f4rtTg9EmYriN14HK4LmqBQqodBHW\\\\\\\\\\\\\\\/N1ElcWhSKak+EKAHZ0DtYw7WmtLgYBGvVjzxsVXw5ccuJpBf2oYWegKwywu2Lt\\\\\\\\\\\\\\\/elfbhCbmiMLktdFLyVlokDnyW9RmZAFge0MLOb7XUQO6xu8yTdDX8rFv0orAyBYP1WH95vtAJ9Lek+RqMWy2OZk0nGJnGkjW9wUfESK4KZxPCueaHESWFWqD+QMFIZFv63jhRK\\\\\\\\\\\\\\\/8U0x9EzHoZ8N3zywUdHorh9qfQZBU6Z4+nuha6ZhkhO0j5cS32NfnG2CwQyHDTwAW+hNVfYuEHsgvE8l6IEWxAGT8EioyD4H9STTUN9tfOk3xeoSRbl\\\\\\\\\\\\\\\/b\\\\\\\\\\\\\\\/qgdYS8xE2ngO0eByf9TyDRdLEVLAqsm6pcAXPjig4TAVtdqO9S8Is4tc+SIkh5mlAt8bPTTOo79Ptx0IcbVpiVdwNmQZp2B\\\\\\\\\\\\\\\/PEZH6UcrgTlDVlbix\\\\\\\\\\\\\\\/68kvHeE7nmuJoFl0vTv1prT7huKMPr\\\\\\\\\\\\\\\/3sN+17P24wa\\\\\\\\\\\\\\\/NfC9oQq5KIzrXyokLvKHJQcUj8q0ZLcyLhIw2wRd7nJLtwQkVOVmm9wzUFDNy81RBgYuyfGyiiFg0vpmCQbCPki5mCcZNFCg+zondQP1QZSU85hH\\\\\\\\\\\\\\\/KipTzLmqraFJyMuuodNGeMPdUgawfjNb+v75PwEtqm5mFPaU+zblT9zAQaW8Y6EU+5CXHVm9yBq+AlJR10dYBmRlv9LwFLARxFHm5aZtzyGD+F\\\\\\\\\\\\\\\/XpKaEaFZnctKHTZ6n2ob6GBK0x1fPB1vwUQzGeIOfTe43D9P5vfuTdjoZlw4fDVG0sYgkDpCNCb42cVMiltFt+6t+A1ENo\\\\\\\\\\\\\\\/JJPKXYVGSYNBXyy+CNjdHPwWsXitnd9Ec\\\\\\\\\\\\\\\/xhSwboAQ2C\\\\\\\\\\\\\\\/cJyrJnGRklovV2cx6NIe\\\\\\\\\\\\\\\/vGrUEVgTLYHCfRBRbQu7Jehb3L\\\\\\\\\\\\\\\/QT08tQS3IPA\\\\\\\\\\\\\\\/6INU7koigWAVtVMOB\\\\\\\\\\\\\\\/FDzNjRMQj8vnjC4ipbVOqjixu9f1H5JHpnC02oJSWxuecPCnuyN7ddkS1JjSrwfVpI5bEjeN61H0NPUI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022E3gfS0RNmErjYBCXITZXjg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022fc36878e8967e0b4fa235b8c6e10555c92fc40d61ce5d990a94b933ffc9e78cf\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000873.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000873.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000873\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000873\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000873\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}