{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gOWWWB3sNGnCTyvU7TE9KiGLyK\\\\\\\\\\\\\\\/wBQ2mMrxS6p3FEFVbH7u3GGA\\\\\\\\\\\\\\\/jGO1HQyuuV6skyle7dp1n2Q+i9tScCpLiBJa8Vd\\\\\\\\\\\\\\\/jq25tb8tzffI9XnTRKk+SHZSDlxtq5tGUNLQQP8tnr2c8SC1+cci4687COkiBU2bKLSY8jypLgM7QMxnpvPXGFC6TZ547NCIGjIJlmg8X+twYhy7nsqzzxRLdG8ynsCM54AVuQESfhs150PLo0eyGS2s5BYGJAmXNFrMYutFZsNyxEe14YjL5lS0GyFEXvcRKQk9n5BvmJzzExpbUh0uUmR6IUhZ8FojdVeWDXM2liFlHa+A+Hs6hAM\\\\\\\\\\\\\\\/tGH7SDoOMpwD9UrQlepPRhtnbagSgugIzxcz7ODApjGMx4PG8HLRUW9d80EgYlCFeUjJbAO9eLUliRXpLAUX6NgCEFbgbegefdkUhaQ37ZF4YjA9vXPa4aEJFuKIgskHfyERD5PF90oQFTbZemwGkJR9RFSvwVC\\\\\\\\\\\\\\\/PrU1me87xx+kP\\\\\\\\\\\\\\\/uR6zDJJ6Ih14uUU1vyJiQZaVHi88qHgTByxh461KwG3Kvr3nfRLBIRc03JHzUutWgAv1s9Eio+9OGwpV6D7BUudkRU6mSxKxsp\\\\\\\\\\\\\\\/pXJ0dro0Y3klIWS02fnwVqXnx+4Yl7ER30s\\\\\\\\\\\\\\\/DuXlyhphf7RLz7m96qZhe7LCcA0Xzu0YUwj9pDJAqY8hNQsYoOaa6O7lF\\\\\\\\\\\\\\\/Kp9hRxsaRNfURpVOi4NqDa8QiImTb5JLiLIOUZ0nAA\\\\\\\\\\\\\\\/F5ImpZjNHkNcgXpnUwtzGwZp2pue9gpBDKOjAhJU3fqJXENMcIymDzw5yR+rqR1L4ijJwrAFB3g1xpspuwS3trLdlNXNrYiUhmycek+Et8WIPNZwuSYWDgmyVSkxAIeFhgMlPXHJjXdI+FS3Y3lK0Avo6wM6\\\\\\\\\\\\\\\/InB+Da4JeNs4PdysFNXQ03nMSv29nd\\\\\\\\\\\\\\\/DsGVbnJ6+YeN027mZ1Um61gwJItmmjAsncGxW++uRcJ0cj6YXbNLXsHHVAiA6VRM2gh0MYM\\\\\\\\\\\\\\\/ZB4nAT\\\\\\\\\\\\\\\/r0TQ+O8+UzH6dVzPP+k1cTAT4RZvIqTtt2HxObuNjQ+XLo0qy0n0GjXfYQYb9NfKDQ9YP+OWsjJFtmzXrudwwXpKg1BSyum23zjNt\\\\\\\\\\\\\\\/HFTuNaRwZSZRbj\\\\\\\\\\\\\\\/FJnWSTBZgqpKLgfdJUm\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/jbnqr8T90Kea8ttPf63euBoH0jjorjsGxYWvgMjpBm0vL5pcEvmX4BNy\\\\\\\\\\\\\\\/Ut9XMwybUmhEdtlP5qoLew6Q6Nt\\\\\\\\\\\\\\\/2i0LysCibJxBXupkviQV7\\\\\\\\\\\\\\\/s3ipmeYhERjjBQKBU0etJEll3DEn9g1Y1ZybnD\\\\\\\\\\\\\\\/QHDRKv3iMXqDfs0Sk\\\\\\\\\\\\\\\/d0BmvgcwNVGAKsq2fYnqK+aki166UZxensHnD0g5GLLYj3YG\\\\\\\\\\\\\\\/XWU\\\\\\\\\\\\\\\/6c1ZNpJJFvmR8NF7X8O3uQ5P7J1xM1pD\\\\\\\\\\\\\\\/MZzl8vblwbse3SAcW7oD064\\\\\\\\\\\\\\\/PVLgHhLNBHq1rPPOgHQUKRj5lfNI5BR2Npi2gP97UUvPkSBU3g4H7iujh8CA08Ud+CZS6b1mrimELLoOjRc7X97m60RYIy7A06xXFaPmOMH0CzewLQTPMybHo6XNzYiU6kUJ5ke\\\\\\\\\\\\\\\/IQrDJHj3wxQkBER0fLdhFZWW16T6zCmoNLp8\\\\\\\\\\\\\\\/+nBUww3GTMtur+YqY6XAn6UBtYppww+PFe1rWPNHm8eMSSYC34NUTbbaF3eQs17t8M+W7CD8ccyedMDEwTVtWAfZibcKQAJKHGnImO\\\\\\\\\\\\\\\/NrP2NZCftrIVthk3LCq1ST3YAOtlb\\\\\\\\\\\\\\\/kk\\\\\\\\\\\\\\\/NU1RO9j8CV7s6hsJPCWQtZS0C7ze1MK+URWbQFy8y3yCmIKG1rr6JejnHOHbOB2uR4GjOtk4ZWj6h6WeKs81tNBUgC+6CYfMg3jAyj6V0oBDFYrQKjyGbHDZG6EtrpiZ5Ka9Z0rCWuMXZRr6LRO\\\\\\\\\\\\\\\/0vpyJfhd\\\\\\\\\\\\\\\/vl1cA8sFtSeBhr3pKSq91YjguYPoH\\\\\\\\\\\\\\\/1wcbpx5kO7pSASi7xAJYQqsAu8FBpolq76odOIQq6IhbDtY1EJzIPkSIuuUI6JEAo2YZmFOqT0frjM5qo64BBZxeI7aRvOWcPu+GOKqE788qCfMjGKSHc\\\\\\\\\\\\\\\/f06Gf\\\\\\\\\\\\\\\/rA3rvRIqILxECK3Xzz1QE+BXcof9ZlC1TeILg4lt\\\\\\\\\\\\\\\/kiCe4ugyiDjDXNp9TH5lx4yZd7z5RcFcmmEEC4z1E72+lVshdkzlTKrScJJd8MgaIfyd0\\\\\\\\\\\\\\\/Fk9ou8DnQPZE9vxVbwlJua1ASpXzUlF85lKMwBz8Zfbl7xzvhsm4KitY+Mzn3WXKnFdYZ66jGWe6w74LMAo5FJh0ZuR1N6dIKAv\\\\\\\\\\\\\\\/OXp99485t4xjq1MNTmJTEUXpJjw+Z1K3hh+tGEUmP4pP2AGT+cRtNbpKptwLEeXVsI0ImhXN4xRQbG\\\\\\\\\\\\\\\/ns+sw5Ig5+EAgaW9byHNObV43tYZWIzD06nfGEVQSkLOlcr8VDmxEkZHeyvNyCxc40\\\\\\\\\\\\\\\/oTVBCHhFLRaZnR7apHfWUnTY8NcDBteGkqGkmOSZdBfqCap+c3su0Eapdcl6+3r0fKSfU76zWLufXvVDisSlKn9s\\\\\\\\\\\\\\\/8WwVQ28uhwbI4G+SNXkqMU\\\\\\\\\\\\\\\/GJNfcmcXENAHmxzZ2uaQZ4XpGglsy9S\\\\\\\\\\\\\\\/Uq83sT8EWCA7j0\\\\\\\\\\\\\\\/CLyyEmrhaQ3TjnHZ1uMFT6zYPZnL44MUStquSM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022tKhIjIyaScqXdWpvgaFSWw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a759ec4a4a9e1056dc0d5f4162b5c224f05e15df662a461dec9eb5970143a79f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000661.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000661.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000661\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000661\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000661\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}