{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022pS2S8MdIRGQN2kys+2bRLkh8FfWH7gv2EU1lwlaseYv30+CJMe1IivY78N5KM1BwELqy3BxOiC6OrMPSUZ5iupzlh4uAPiHKRoIa\\\\\\\\\\\\\\\/XdWyYSa8WBeG0OgqY1JD3TYbmKE3KlHYsmsrzxKXuJ8\\\\\\\\\\\\\\\/dsGJMT+lNiuA2I43JEGomUTVYsyyJGiJfwQavFQxa\\\\\\\\\\\\\\\/AErR2idRLE4Zesb7OFhHW81WUE1WcyBoMTcXcBEGEdWAgU3KtEKS7uR1wPCP7wlY41WpYwiIOqBImoY+qeFDZSKCCyhWGE1ArozWdsOW3HaU0rjFs0lz4zRhXQEHMMeEKJ\\\\\\\\\\\\\\\/nGNzBRYrErnm0YjRaVcyS9ycpUpF0GmHr0aLH2FhVFgxKk8y6FQMi41rHZsO7MQFaIkB1Nqw7PTY14lndQml9TZ9HQ1svI6dm+xRCBY86o2bqceOEAWg+Czn1lGKKA4Tijs1FuFxWWDCJbuZ58j\\\\\\\\\\\\\\\/z8eke4NIIsVJlSY8lQcIHOp8XHn1AjlfXB\\\\\\\\\\\\\\\/rRdWwFQxW6mTy03Phh3N5yjnSSQwUKuLiC2JT4FJOH9jnrHJfVQfJMTpnB9sCoZMVwHEv4Smu8OVj7\\\\\\\\\\\\\\\/IaPZo2HkuAfINfFRMSpmujTyCyobyWrrTbxrAGrg34oZIaTE8thMDb2bah32Uf5OBdMCaFBzVHY449acUb8iJc6WrQbOa2lr5oxsV7fa4kapSJYhQeYSIqg9B1zCed9lDMjQYEWsP3XbBa6GXTguSdQ2Hg9QUa3KTVCRbXXvGLAAVu9vXGsunLRARTxdZeVX7\\\\\\\\\\\\\\\/4v1ms+K5OgJMpvZNpZ8+v5ZbbDeruXDV43\\\\\\\\\\\\\\\/XabPFA6JLR+QjGXqxO8pcjmExqy\\\\\\\\\\\\\\\/S9hwCxht4WGhToOK\\\\\\\\\\\\\\\/TVsXGPJrqb1+mUKvKPt9FVCBsxEZC+QCgmSGU+C9KLxISSqsIJK4A7Hv6gJFP\\\\\\\\\\\\\\\/qqXyFf7dI6qEgitXugHjEHjREn0Sc8h6e9RzGO7S3941sNEW9dA3PRleGXxvovZChd7T8ID\\\\\\\\\\\\\\\/b7UNLpyfLPU95yNPE5vcJd3RzWhGeLu\\\\\\\\\\\\\\\/UxHILzEhos\\\\\\\\\\\\\\\/qyiyonQogEQKFL9UeHmcbdqsjB\\\\\\\\\\\\\\\/YHqeSXJZb\\\\\\\\\\\\\\\/pMk1barpgs\\\\\\\\\\\\\\\/gfOKEFbA5apCsoV2PzIix9DsKUs01TPrwds76aSRMzXfiBaXVTZtPPLsxlLKqOcyWLIS6XbRPuK0oJYtysligl+P+\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/KrjKvQEg1Vo2YshES4OIL2ASZOoneXXdgR6fW9a9y3qJhcQc8gOG2mCbMFY1Wb6Znwq9p3hPdfEhjH9Qa6vddkiYBAQsjqTDILvH6m1FiGc5C2fqbLcsnL2HOrYoggyj4xnwFZvL+Jz6L+RvxHuvEcRBm34m\\\\\\\\\\\\\\\/hn+NN9Fd0sUV6JYE+aO11974a0VIriLnHHBqCL4jXM\\\\\\\\\\\\\\\/Jt8Iiql9ULA0UIHmGNmWWKHTxQXNZkmLwENabHhI\\\\\\\\\\\\\\\/hKpddleTSi2\\\\\\\\\\\\\\\/JddFzyzev5hjpjXalH8FmIDIR0IEbMTcyiD11iGRibtS8DCmBTChA7LCTNx4k6\\\\\\\\\\\\\\\/sDscyaT2SxAsJob1ArD68ZexcuChVEuTUOQ86gq66SA0DJC92vzt4SFlJu14PIyxZrDSprZ9HDYdbg+svg7ri9C8Jmr59ywEC2ZIHkASXZ+cx6ywql1r4wOjMw5SbTekJQWAgstj5XHS9zdKMBVBiDawpB6hLmg8dPQcRFMy5Uip\\\\\\\\\\\\\\\/1qNy1b\\\\\\\\\\\\\\\/+pua+2NS18OGdHPoGk\\\\\\\\\\\\\\\/jxIY0LwuGVnbJ9nJMLlZ2PZ3i9boIfvLz\\\\\\\\\\\\\\\/VYLnE4YfoSCXqCun955rnoBZLIW19\\\\\\\\\\\\\\\/lLIO2VFKKS+oQrnCDKLAE6UeC7hlkObZbyAN8VeL4FaSWX10da+7FQO6JOgLbwQ6sE\\\\\\\\\\\\\\\/mYF9jjEuGS+tpq4FNtwaMx+nQtV+7V9Henx0Cwmsks0mc1H\\\\\\\\\\\\\\\/V+I5MjH+QNTGcHzlnF8ahRuiW1OGAdwuTNwm07MdSebN6vES8kht9j8XYNXKeiwc6uhxOAQCU+8dX\\\\\\\\\\\\\\\/x3K\\\\\\\\\\\\\\\/2FJFmudkiqluYxu1fmcwSCpu8tb7MfuwLZi7cRz8paVwJMqsi3Xv3yOg7t5vrYXc6NbZw8q8VipRDfesUnYgkjTx726WQjihIOJwEKWsGkJBxAdTXdgg5CFdQocFfKByVC+GRcv8Wzy8SJQERD8PeURA686Ni5j+AtGHGwWarEbYJCPsvwUSzOP2f0Lh4S5V8PrREwPsVQWo1rlFIVUQ11zmDbvnxpgM2LBLj+sTBp\\\\\\\\\\\\\\\/dkOetXj9eYpA51y+76L4Ouri6r05KAEvnSgOmMT9j7jFWH8ckrU7VFPblekD5WThpvD5yTWfSmBP0JkQcoRK9+TtRDFBdcHLC\\\\\\\\\\\\\\\/UKRB6qEF6R5lx4Gybrv+aoqLCA89sXL1qeVGOCvkqzQ4V+bITIL\\\\\\\\\\\\\\\/K+kas1864Yo0Vfs9KmE89\\\\\\\\\\\\\\\/YSwDUxnONiYLBeh26EztuEyJxu5NPVHGtHVQVNkW9uu3I8SZjQYF794uc26sc6Rc1usxBEWm47dph+h286uTp6KYIcWzitSw2Z4X2EvhRRChxmE4CNF+Aorj\\\\\\\\\\\\\\\/hWG80\\\\\\\\\\\\\\\/NFPd+8Q80diSks20TO2xu4De1PsbM9VOMfjXllMaZZco07llGsYeEJbVaj46s\\\\\\\\\\\\\\\/gLEwDrLYsJRCfmw57AIYbnKYiLFcpZAp07GsXvlHrlNlOy5HvUZdPPaRpXtfY=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022T\\\\\\\\\\\\\\\/WYvzU0d2FcU\\\\\\\\\\\\\\\/79UDkU5w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022cbcf0513e2d14c09330b8f6ec67fabd36d189bc1d33f18a071b002046a43b086\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000952.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000952.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000952\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000952\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000952\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}