{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022vp\\\\\\\\\\\\\\\/AumwQCTfmflZIONMUVYZWtyGlvYDUveB2Y13ZGBPkeq1vKePoqXYF4KOPZDFD3Dn+M38lPAoyRTfqsHQ68um3sthpV3ng1Ht46DNsvjpAt3yJiaCWSTMaYBZg\\\\\\\\\\\\\\\/wt+xjMeUnfaZV5yLFdaO6aQjGkbmKLi8cn6DOh08ZiB+z3rs3OJKfUIwNqJiBm3uTniHKq7bYWmEQetmTgNJFKjyyblD7+PGGDXAEyMkPLYntdNEUzdbuQTVlhAOrzaYg2OW2w65Uu4f+WbPYtiLOhH4QrrFaQ6bQdFvyovz7TRCp8jhOJS2NofaZw6zCQj53FpBAzUN0F1lnT7sLsm3cLTwz6TlRhzFkmmULRhOIN5RvMWJjLS+63KAOYHGiV9jXjdN1YPdPj6eg51ZZTi4AB260A1HVvd1eRWJDfDQm\\\\\\\\\\\\\\\/L8og8PSrGjotgqEkPC2TcsJFP8O2mt5GN91Pxxl\\\\\\\\\\\\\\\/XKjkfbSkHljQ6t9OBu8twozTHaKo2DqXJDfqMtitBgddViFFqXKh2QuWJN8FKHri2xduW9QVaJSbsIrTKGENWbvOjQ1VCuTvCvTIG\\\\\\\\\\\\\\\/nJcmMwUj8QqZgyQ6xQF2soHXcQAZ7flUv99tF52\\\\\\\\\\\\\\\/ps\\\\\\\\\\\\\\\/r3eLxXkBqu6dsfZX4zx6B\\\\\\\\\\\\\\\/pGAHuSYxNX2SH1IVR1u6maymEh+vqFNRDuEgPLLUZSd8fJVs4pkBj+HoJyvlbDPJeKOUTpdoKjCIm\\\\\\\\\\\\\\\/uAFwFE49tQsvHXwjWI0088HssWm8FQZYX+rTesRhJo2Dy20K53lMKdZ2M1DbmR2xBoS8U4+q8WbPD+C+oazsYmX+0iMlX06flpLIMCMBkPisVB32ox2\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/wu7DiudtHF++2q\\\\\\\\\\\\\\\/iDisfUgNCBsKuUw16JwQDNMp6EY0N0PYUuSnJuRgw6A0mAJu\\\\\\\\\\\\\\\/SVYDWewhO+chNyhiitGJOTYFFdRDWyQFNL6c7gJdpSfcj6mtilVSU878vLbSXqYx2ODqkfLk9fW6ee1w73gu6ehs7cAg4RHPnrzWWvX0MknIm\\\\\\\\\\\\\\\/fStZ2zQaRWP04\\\\\\\\\\\\\\\/8pW\\\\\\\\\\\\\\\/V4Tf\\\\\\\\\\\\\\\/9NM7xsSm\\\\\\\\\\\\\\\/FyZTQ5T+3VI1xXQsLhQdq7MFvY3ENv1rHPZqbf9WOrrH3AR2xh6JXFJMloEWgq9OC18VgIgdK7kNWpSUGfODtG7IvoYpU4ES2ZzixXe1pF\\\\\\\\\\\\\\\/W6qecSsKvPjNtTdn4bQ5ejSXah7BjAMIonWzVJZN7uhi3e96dUYRNKRpUlNf4N7JbJMZzumtwMUt\\\\\\\\\\\\\\\/RwFzAX5Y6c3KIUNVU9xq3A+XADm3AultPhiES8iXIoSRXHDsM9PCYHJrQD4SlfU7TAndOBiUy2sMq9V4X\\\\\\\\\\\\\\\/T\\\\\\\\\\\\\\\/LYgblB0ECN0UrU4S8VmpXFaxwlGbaaWwIxh\\\\\\\\\\\\\\\/NYLWS34jGWJznXhSQWQdJGRrTn3jb88w\\\\\\\\\\\\\\\/rQaHwgEpY8SHYKo8xH26ad36xTjiwdHoBO1Hyc+xAWauvpqhw8LAYru9VUKVCZLNa6msHhGGWK+4D8Z4FAb\\\\\\\\\\\\\\\/n+uP\\\\\\\\\\\\\\\/okQpwd7a85E7j4V1GULxS0m30mrsewZ3qCotMmpy9fWqnMEqlIG\\\\\\\\\\\\\\\/la4I\\\\\\\\\\\\\\\/5xE40y9FGgmKYwh1KuRlfojhb\\\\\\\\\\\\\\\/WBy1rDDq6+SFzl1Yk91EtITQe+i8JlQrPaakT89kL2h2KvguqPQh1dAqJz\\\\\\\\\\\\\\\/NcaR6y51fByrhHoYVCoX3nwPwcKr3zNq+oxOI9FGFKaDFavYQj0Zh1L1yhTfJ2bLcqLFBcQKiQlPBv1gg3vTGD3nk4bXB72EDwYi9PMlVuKLK9OV47OnwRbYLKB5HWCYcc8lYxaOUpUjbYmBn1uaW8zcxwrOtwh+0hOYK5K3qTudEL1jMlZDyROCx+gz8DITuvygBhaMmhoG0mPG6EEHMiuWS9R7R4ZWZPSH7EkY\\\\\\\\\\\\\\\/UjRAbW7wc\\\\\\\\\\\\\\\/fv9Sh3bELzV8anV5OVWPIY1eOHrrJ9I9prTNkB2Fqw3mp0LaHKYmoFKgaUH5TqygU68DmjBykjrHoO54Qfy+ErosqOpah+3Bf1b6ClxZqlMcOl4BZGXjZd7HwQxG0MbubJrW\\\\\\\\\\\\\\\/j77q0TqrVEuCvjQWvFA6WOHYVqwDCXy8s4kqYVw8tX7dPnnpdPXqvB\\\\\\\\\\\\\\\/vvEWjYPY5kfNGtcokp7Q9Id7I\\\\\\\\\\\\\\\/yxyO08+WiWYIU571KDBmmjg3fLNuk9ItZmA1d3dTuRX7q9nTw1vXcjA4uDUhTT1KMarjpDZ5zmKbxDgjHmd\\\\\\\\\\\\\\\/T9BHEuy+IgZXxBLAR3fcxmuzw0mHMv11mb2jxLmxlUJWSiPs1uBGl8f2+0se7CPl45bF\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/vfJvcI9p54\\\\\\\\\\\\\\\/2FdWy0nbRmzQ+3lFUqugfrNKF6h\\\\\\\\\\\\\\\/qjSV13P0ToNwOs8IxW4aTAGCnXhCNe\\\\\\\\\\\\\\\/n\\\\\\\\\\\\\\\/G5cdzOrtel9kCbnK1Wyy4DAXaQz9ZgqmNv9nc1wr4oz6VjC+bxAqksgZWl\\\\\\\\\\\\\\\/xIqx2HjEI4ioCVs3jNrAn5DmXtcVhUYuC3GrFaR457MhIFbBSv7YZ+w\\\\\\\\\\\\\\\/xYSx41DEpeFlVsQbi7LnCcNtcmtdAvAdAn3SaCmlV3n3MHfQsl1hOUVRr305X0lb7bZaTVyH6aiczLP9eHuESJku+4HTe2rINnwl3amsFeok3dxcR7hck5QOYFux4psGULTMUNUIZMiu+m4o7XC4Y7VcEAoB\\\\\\\\\\\\\\\/kusRWn1l+IIe+nYhr6XffK0ozAS2\\\\\\\\\\\\\\\/m7i5Sok5Sos4+8ZlMkc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022WDkwmF0FLrEwrn\\\\\\\\\\\\\\\/hyBVoDA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b57fdada42a28c9aeb9e7c3e206948fc623b0e25fb38bda95b038f5a8f15666e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000550.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000550.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000550\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000550\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000550\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}