{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00221s3iPdAYJdakxnxQ58dO+YCPguJQvC77XDoQhQ+ePUDoTtgemceW4pBpXsUK8+41IYaI03bbhjXOmlJ6lFHUzs13A33TVkIYiLrhDDi5sX50h54LRVcS7S8c9w\\\\\\\\\\\\\\\/9wOfddGoS3P8S6Fc8wwAAxrhEiN\\\\\\\\\\\\\\\/E0wXbKa66XMnbMJSk8qQxy8S7WOMGsSKMUeSJzWgm991li8dHPCHLvtgwc4Hs8nbkJeq+FolepOG2vdzji5mS5GAXEbao8GKKGyms6iB10TrRxKg6pS2lfo0+96OZ0MOoVupKRciui\\\\\\\\\\\\\\\/qQLDVb2fF6NQl64FJxg10xgcVkwh3H6Nf3zxDyYsvEzDUIuUVHBlUEHgbKkshQaPudgXmT3STQ0e+LsDmuBX7bjWf4iRgAv\\\\\\\\\\\\\\\/WSIhPsr54RV0hHLzR7fkE7ZtkDB0Dc2RTiYteP0MsA8NyTwVwdBF\\\\\\\\\\\\\\\/lignqrrjJ1MwOAhqyd047oDX5h5YNvO4KK+XZkXAe\\\\\\\\\\\\\\\/KeoRqIUTGnv8msuhNopYKoQCtE5CJ1ypehBBHiAoZcoMO8pkJ3VYAfj7+1Cb2qjvmZ11DmP7+LNA1Md6G8x\\\\\\\\\\\\\\\/Baq8H2joMY7SJFZ2c4dEBSLKUb9iqNXAqa48nndI5oY6su+4DYwYg0b7I3uZGaU7HCsrQRwRzC9ID0Tu8IVL7vcTp3\\\\\\\\\\\\\\\/2hrjjRlTBMkCWo+ScE\\\\\\\\\\\\\\\/r6m4TaEuy70Xp7S51OQdImyDLwvLmb45+Hm1jn4OgoEHglInEmuX5M5xnOD\\\\\\\\\\\\\\\/hZUFB1wnwAU9zE+2OLIKG3M1Zurh6nKCTF6hX\\\\\\\\\\\\\\\/tsQaQlPGc6\\\\\\\\\\\\\\\/fbPsZUBFHYODW52FHCvdRqWUoT7R5XcF28lCZVMBIFJDDTGS3ieZ518JuHuX2HtpxmfN+7GmFTgZY\\\\\\\\\\\\\\\/OKj2VU13mLaiNGd6qMelQnWR9U73SSsZ5sCyOzR5gdpBNnIm8XgoSv\\\\\\\\\\\\\\\/LZhXtMRpzO6n9oSSyJcHPR7FQIF\\\\\\\\\\\\\\\/3m\\\\\\\\\\\\\\\/BpAa08j2PqX2rdHP+V8iu5TiNaVA3b9yOh35lxMQgsBcdmqjOI\\\\\\\\\\\\\\\/tFgCL0x9FV2iXt0qeGF+TvcUQtVw1v1wssom58lJ7KTCzD2amCEOnVcosd+jl8Mu\\\\\\\\\\\\\\\/JFWx+Eu7ED2wHfYPLf9GDzNdLel+RsclAIyCcnLI3iEtCF8zKsyZD0YAOZHVE50GShpLSeG0lq94\\\\\\\\\\\\\\\/ibPW1AxvYNg84Z0MqCInBmK1sHK1WV86\\\\\\\\\\\\\\\/vAudcwsug2Oc7Q\\\\\\\\\\\\\\\/cIDjBGnX7ZPXfDxyoPUscYmrXs+qt0fq3Re+SdbPjb1FQrxltek6CkQ9DuTtX\\\\\\\\\\\\\\\/fUuAJ4EtZo7nUd+x3TYfKowgtT5\\\\\\\\\\\\\\\/go0zuddZ4l\\\\\\\\\\\\\\\/RhEk9cW8FCisA6CML61v8i2444U+ScQ5ccg6RpYEJ63CiSmL3FiOWz8A9GqLbhbMYmr0alOWFbEZ0zxFS27hAOLi3HJ8abE8Q6pl+OWaZ4RzYzgon7G+\\\\\\\\\\\\\\\/DXi32UQDGI6qBbwoAdJRPS5QU6gv0GWJOsrzf0zoHwRbSfNaq2sQY0KusNVOvRCL+Yp1Go3FKzqOl+\\\\\\\\\\\\\\\/0mXRuO4mtWo6NF2s4cYpF0eVGU8Nk5QN1+NQoYOG\\\\\\\\\\\\\\\/ZfPQJbY2f2zo169gU4U2fxC9HEC5aTpg4sGJMzC3NRMivKun68wKVND0VkZ6ejCDyJJrhRv2K\\\\\\\\\\\\\\\/KhYQwbMGkjS0qBgELyhN\\\\\\\\\\\\\\\/3IDaTv2Oqn3Q8KOKKLnxzSLAosHDY5TREVl94aVKzhVqNG0XYZhN1FDj28011Tf5xDskpO4fm7YZgvQk1KxXL0u9S63zm5a8sMr7WVdQJbHgYOx+V\\\\\\\\\\\\\\\/o4WwzuZvBJ3JgCR9KWd2RBRW2Z5t1QG5ItU8OsECh7SB\\\\\\\\\\\\\\\/kvwu1lmTJt7Rwtia7mE3uUrZ7AYCHPjGbOxNWDZIPRoV1RSZHuyIUCul4XgBm3xbY2jwc5jScxEJnnMO6r5sODCmGQFgZcxuAluBWv9f+iUjtQD2cVeFYgobh+rQStMjKaGXL+4gy7apk6ivNQ2u0sbSVzRwmuNLJNEzdBT6B31ZujuTM2kxyd9NV1Ox3VlUd9X4fSHmVMJfOYmKtykhPqBwdWJcYChplCUKjNSC7cufhG6if1XUbUvl0Yq2o10qlB42mufziYuHRefkjsQfEtiINnLBA3DViW25uV9EElJ9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/qif+7F3o1VG\\\\\\\\\\\\\\\/DR4AZat5H5MJLBBPdVkbKJSJx0XtDR7CbTKc8ORMQYnqeSKWnzk56Nb6yvuORN7SBpAXcYKgvasPmYTA+rICxlys\\\\\\\\\\\\\\\/+1GUr14Cdpj7aL8Vp00OkpBqf1ziDo0cuwAT+y+\\\\\\\\\\\\\\\/Uq46vbQwBMMvg58bVgd73I67FXD2e6cP+fhxZoukYSX5cgAxe040WwRD8xwYG\\\\\\\\\\\\\\\/O826Yq3fEtHk5PAPHQkaM1El6Ms8pujYOGbnLjBz\\\\\\\\\\\\\\\/e7S9Y1gcOAGome4Jp5Ro3sJKQaQPacKtW40JaNoMmQLHTLpasJil7SSz1nSVTaD\\\\\\\\\\\\\\\/txaxSAAD1kQvzlSt0oHNiAdyXtkQruI1qnoPZABJd3sfMV4lfuw4ZZ2AmCqf3J6lDjrmfPSK6Ax+t9ITwS2uzi3ErkZugdqHscXpR1uzdVhVEVwgAdT3JUgxAsfx6ty5iTRkuWCZxBEazrSFGz54ZYa2EYreF6m+x8rRF3Lok3URsL\\\\\\\\\\\\\\\/Y4NB6wuL2RQDprI5kKi22X7OCSi7BT6q\\\\\\\\\\\\\\\/twuE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022f6oXtPbSNxj8d3tmpVZo9w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022610db01402e1736b78ef5320e2da42a62430a9ac64013214ebfd4650a795b1b0\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e000550.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e000550.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000550\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000550\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000550\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}