{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022UROeuEvRnCqOnOhRNuRxJQtzxRZH\\\\\\\\\\\\\\\/ZC\\\\\\\\\\\\\\\/WmWOm\\\\\\\\\\\\\\\/iSh31X0yQe3hiGh6griT90CjabiXaHxdGJFeiIYvyn54drKSt1mPRaNLrRAdzhBWfU5ruZY3Wc\\\\\\\\\\\\\\\/0\\\\\\\\\\\\\\\/b9XU8sijN6viXNBxDCr4PeB6caRLx5Wv9GsHOFtd20OeIp4giAqdLrtKXT9jsChzLV2tumZhorJIGBAA2PrtPEGRG+BhmhRToZol\\\\\\\\\\\\\\\/goODlzwbhr9\\\\\\\\\\\\\\\/uSw19DDGExxDZEdCCBrhsB5aqBXVJPSjrJ\\\\\\\\\\\\\\\/xXccH23YdYWpKJcjW8fhiJT2pMIcqOWIUfL1IjgJpSQnb7pTBQ3iqtXQfuuV1eHD20EaDOS+K8rrHZkcCdEsTv8tBJL2QkEsfRuzVdFQDHWhxqq+qnG\\\\\\\\\\\\\\\/X2Hqo8x9L0KZOVYLFqybpjxESeikanZMgmOJZggLbkBSzpT14W\\\\\\\\\\\\\\\/aLbmfz1dLIuU9a556KoLYE1xn94xWXEWN0mrDQcLLtw3XH9U5gxwKoTOQRI5fFCILN4E1l8Pv8gjcfDoxnCp7cwt6rkIFjq81shclu2PGZAxgVUiSTINJ8P+UkyguiRLBrjX74HFnotSwOrg4Q8Z95FmpZyy\\\\\\\\\\\\\\\/So8uQjzLF5MokIB\\\\\\\\\\\\\\\/C3FB+SLyrrEHnzDSOJcutHMg2INcLZkFUGVxAX7ML4oJo+4B180RJyG9M1l81hRXoSCBMJxq2pfVoX5vuLGC0nO3YxINFqivgyDCucjw60+DH2FGfpHiGYcV5Zz+EkxVnfJVr1rd\\\\\\\\\\\\\\\/yDew5B\\\\\\\\\\\\\\\/k9z6qu72TYstKy28TIsQbitljnMDlKI+lgORctC3FoVCbgSRWUHurMjfOyvUEY67hxrrr2Q0pe6Z2VGOZhTnvhgjPfJ042RCSoCIF4rCsDQoiiJ8BzyvhbAK7KdtMQ1x\\\\\\\\\\\\\\\/0ODaFmxLDM1KFjlVvX7jmBlmyIVwG3CPY7\\\\\\\\\\\\\\\/Vgl\\\\\\\\\\\\\\\/8coEfafW+Nk7OEXbjJN0GfjvASZU6YkC8zLhhCr3\\\\\\\\\\\\\\\/HmxzBkkp+vVRHQxkDAKI\\\\\\\\\\\\\\\/NSutROZ6Cgxe5vOLw4hUPBPgOL0Run3bf88PFn1Dwr5dwCvKhnM+bGLa2zGDrPCfxwHXFa0lDGulI3WN3LirgIhtcz0gttAoOzi5tedAK+bkF79m8j8jUY4fy+Pg4fgke2Z2DUuUatlcC3UIeOwmLu2I9YPK7y8W6gcMb3D60ZpOMnSPpp6HbVfkfrAlg4GWToktmVck\\\\\\\\\\\\\\\/RIgUfDvOVJfVkwOqbmfya0j776SCKmGxHIY1SiLq6N5Dj7QiDVdeAsTi7tZ9okRvkQw7MSGc3lzFK2uOjOb5P03B9muY\\\\\\\\\\\\\\\/YUxT\\\\\\\\\\\\\\\/5LHa6+o2WORn6yr\\\\\\\\\\\\\\\/lu8TGKtXwifPhbHZOMp5P4XYJfExeZ8LO7XN0cuOJ6NUJ5sxQHfZDrRB7kydGJITZEai1HR57eJ3qD5udJYQTk3IVlUqi75qg3Sc4sqAsuieruHZ0GlcXDhJ4l1gIefnlbGhEaYk1mXCHX08Rqs5tPUuKUPgaM2uuG9dxOLlHAYLUrr2bSw\\\\\\\\\\\\\\\/o5kH7fEca3Uuh+K8prYSf\\\\\\\\\\\\\\\/cAvJMbHpCLbpyR821vECFmaBZ\\\\\\\\\\\\\\\/MudRplN5WB7LpzulcS7rMF820Ks7D85yew1UR5\\\\\\\\\\\\\\\/25vhEuQ7fvVurqwUAsklL+79NNq2By9M5gVeAD\\\\\\\\\\\\\\\/4brXevE\\\\\\\\\\\\\\\/vaA8V9XSIpPiYUxrnIhkyaaooSP91nDiZe9CCsx\\\\\\\\\\\\\\\/bxkEQvVrb6OhA\\\\\\\\\\\\\\\/uJHtnM42732yCddO3BNbJ8mnEBIcB\\\\\\\\\\\\\\\/ewrIusPlW8yAFN45hbDuQTH8YTAtOBHfco4+6HfRQrJL9TiYlQqT4mkNxwD566i4NY5yoASudw2i4xwTCSyjbd53NG9aVJ\\\\\\\\\\\\\\\/x9Nz9bvMY1RDmCo4gIreFiQxB1eXbzSTn72XGZbTlNgfsndm3\\\\\\\\\\\\\\\/TRJNDgO\\\\\\\\\\\\\\\/HwW7xWbMDSjXmooghKWS4koewq2myTVtuAQXclhhIiZBIyq9UBEgNFdvTSgu\\\\\\\\\\\\\\\/TEpaSR\\\\\\\\\\\\\\\/1roYH3P1UXHZSeCL2KZcAlPUEUDLkrgVdENOBEQ5a3mBidN+Ks+gsl7oVrc13mjzLyQCxQqxV74DGnZ4Ft1IkIQysXuIFb3aIwnzhU16TvUt1s7B2t0O23eDJRX37LBxL+Ua55puGAzsqxqw\\\\\\\\\\\\\\\/7Yoow\\\\\\\\\\\\\\\/RMg\\\\\\\\\\\\\\\/doNTu9fVu0dsFp6XRX7IFIN6JtKacICbw9hZ7uws\\\\\\\\\\\\\\\/MiP+D1t2Ntax76chE661wwmd6yeC\\\\\\\\\\\\\\\/rsqTyddozrwtirrMJFMu5DUhRNb6FCKwSnU4fTazz+8KqjqvtP84H4R\\\\\\\\\\\\\\\/FdbRMYB4xUZ\\\\\\\\\\\\\\\/+E9Xil1ERVttWYxUKuVykivnA7h94oZbwM5F29WhxGszQ0I0angFjNzycNuzxehgJ\\\\\\\\\\\\\\\/vzXCfMyObpasW9b7fyPeJ41ZBysFk6at9RemwaYqcsZk8cf1NLNYEl4R\\\\\\\\\\\\\\\/AcOniW5\\\\\\\\\\\\\\\/JgT7ihZQ8JEP1Tu0EtFiursDAB4fqzUB6iNx3T3nAZ1lbAG9MBJDdXCQ7vP2n9d6\\\\\\\\\\\\\\\/xbai5Iah83ljH3LTb4csIAjUU1vn4Zg98zC6S\\\\\\\\\\\\\\\/vDXTGNe91gKYaUcKA+6cz2sNnnhGa3+6dXgY01RzkB0Yrw7mODd8QoLjdFXllsWj6\\\\\\\\\\\\\\\/K56VIRseWxtzm2nvfw+H2ftM5hNZ6qvygB7QEQw8PrLcm0NKf2zNKGwnixOwYMboYOfNgHb5CtxhTki7+aSasv4HWnoluUBbVRQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Axbf982D+TLoIyJ2mNdb\\\\\\\\\\\\\\\/g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002255fa699825535566408914316ce3221eb6f111b421c7a4a03ac2b095f4d6185f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/1\\\/e000617.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/1\\\/e000617.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-000617\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-000617\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-000617\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}