{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ik57P0NqwBTzdrzxn3Th9+fbUnxRn+jqCOF20BxHxC50yyx37BDg6ZPr5cxoSG1ULf69a+LEXaPCQMQWIFLlja3Q7L+sIbDN5yUm56Fq4kqiAbGt7xTzqoekoR\\\\\\\\\\\\\\\/x8Mn15nXthf6icsyLAjrdj+AoS9yytDJ+nqSN1ypnQU5anENWsRxqwJrj7s6p9KwIvCILiTUKUxXjfkTXHKhBhrXKTdM0+u8uu6Vy1btIbNuLynw68yHY7o7+n2Ksw0Bz3jtLWiTJ\\\\\\\\\\\\\\\/lq7aNan5qvYxcQ7Vs4Az12TxkEIozOot23AUXhhDramFx75NpWG7RMHaRuH20eEhBKHh1Ihf+s35+gorbdHm\\\\\\\\\\\\\\\/BQWELAI6NATXS0TDak0UTPM9a9JqbS\\\\\\\\\\\\\\\/bb2YnI0esEs6nRk5kKMUwG6G\\\\\\\\\\\\\\\/qC4OJUrt+CPfRozhjS2LwULszG+0\\\\\\\\\\\\\\\/LPvrhrm3w9HiGtvkrOUqDvPDS6XIfGBtvbbwsnJXn2fSeZFdo+b+yhUjZnub2Mk8Q+tzPnYwbo+2cOtDT2f9N2\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/aeTClrlWyK96BsN8kR41aUYlerp8N5X1iusT9my\\\\\\\\\\\\\\\/B7C+B8mFfs7W6OP8PNvZkAoThEBesA6BBN7zecjEsaoJLLTHQAi8v0i7I1MGd34KKXlhu4nyjERXf9Yol4U+SnYXZL\\\\\\\\\\\\\\\/+DKFxDBhCmCWxYeAfrZxXu5Ah52nBBvwMrCprugMEfVszbkCFQX\\\\\\\\\\\\\\\/3RWAs8OEFP++PXFDBeYY8XqDZ5JO3tiG6wcnDna4YyaPKAPEi3LFd5iJgoYoq8sZ\\\\\\\\\\\\\\\/+gtG8Hfv6xRjdAL2uVzAXiFKmkMXGQwjzkW1WyvfQuy\\\\\\\\\\\\\\\/tH22EFWPy62j+ij2op+7cd70unmnroE3O0RkaQ04mfVQs0Kuw1hwmegqsmDfLpnYM1i\\\\\\\\\\\\\\\/OdvWCCiNUrZ5uCfrGDYoHRFL+btLzzySppc\\\\\\\\\\\\\\\/4KojLXvVTvlHJ2geHTRNo3+Z3F6FxBDiAIFpWA9jkHcJRC4Zij3AUM7jGA80bu\\\\\\\\\\\\\\\/tKwvVbHz+02YXOX6ifJ9SD7hK8015Cdazyi93lsH6csHuKTGnN5qln0DqkhzCPuywK2gqgmZFyzNpYGj2fTppI4jGbJqlayuR7dsER6WOVvDIs96vWOUa4z5Izjuf67Gc5I4D34BdB1w1HF9DHRjC1vviG1tylwZ\\\\\\\\\\\\\\\/eHyMyWAGwyewNfO9hSMWcEkHecM\\\\\\\\\\\\\\\/gJeTt3lwpW8V6FC\\\\\\\\\\\\\\\/kCAa0vEmVmF5+gB9jMLBp1ceGUZUNizaV18M+TrTH+DPFTzynXnYYJowW5bHIeHiLvZOhKFeo6i8cShVBX6rFqH5EzYQYsTbQm\\\\\\\\\\\\\\\/6YBXNdS2bVq5QiSwrf7hpXf8beLo5CCzt7D6fJODP1uODSI5h+GkiFvjfoWkm\\\\\\\\\\\\\\\/Kr0WukdeB03HBKO\\\\\\\\\\\\\\\/6iscoAkxN+YKYbyejcKE8Y8hu\\\\\\\\\\\\\\\/DCl9Q1o8VMxiPYCg5y5J6HBV1j1tVbbBbggyGINMHhEdMe182wUvAMPQrIpscOPdVDM4Ui0D04CnUkP0s1mqKFRwzktNgQKdjoteJPsl72wIbWsTVRhTKGgSsA9Jx9ZR9WK6fZ4KCg9JVfZRP5dGrUF9b9wFjGCxVsyq3OPiNVfY3PL6arksE\\\\\\\\\\\\\\\/3c57VH8\\\\\\\\\\\\\\\/Ct3m114jPHPZtdIQx9GqIS+OO2y4wUASuT+15uwNeabviGEAELExE2d62QpgECXZRzLrUgzeaSlGQrn9aTU7dqYsSTh5S58+u\\\\\\\\\\\\\\\/6wbnHkuzkkpfQmx0A6bBOxLJFkBPpviXVgxWBZVPS00FlEcoAoTimEDNKfz2+qQSh6UG9Zs5ZeU7hIszAT4AZ5F8c6w47x19n5oh0liPGAECOdv2gcqQPBC7oMppR0M54Tbf+bouc76n06\\\\\\\\\\\\\\\/dX6w2d66wcvOFS7D3gJXMYL08fvW5\\\\\\\\\\\\\\\/rheBKOSUbxCpn7bMvEoV4rlHXDwzCL3Zre6DUAPtmQhiDu2ilCzhw\\\\\\\\\\\\\\\/VCvrl2dXCRyT0q\\\\\\\\\\\\\\\/7dpAfvdOvfj\\\\\\\\\\\\\\\/jsF762TA+cpKWToapwBO784rjHW58mnE\\\\\\\\\\\\\\\/Ifw1kxTg1Va2eAhplnncqTSPFi3jS8Y2CDwDq+O+enzVX+O\\\\\\\\\\\\\\\/gBMUoEazX2PH2TYGnzVh015MAhIOvjtSJ7qk97C0di050\\\\\\\\\\\\\\\/fsUSc613RVK1f5Xp6xCaZcJFWMLl3S8Yx23AVzJCVoQAPocOcfBrQO5X0U5O\\\\\\\\\\\\\\\/jp10auoL0r7qFQ6\\\\\\\\\\\\\\\/uSjD2al8wcNKX78pfYNNo0sp4tZYpxBOiVQkRXwUyDhjqR8Kne64J6gccYqMXtgDhW9aIZppXl5bhyuXh3ibx5cxkQ++5\\\\\\\\\\\\\\\/ulbIm4HhwW1jJ7Uk9g9um+rHfG6wemFKJ0QL3a4cT57HvYKIJLQGRla12IGzZzPeZtODAKWskbiArpcfpJRvJRJa8\\\\\\\\\\\\\\\/3WaIu1CoW6z8Tb4+jbHf99zZnopWX3+yUE9VNPzJm\\\\\\\\\\\\\\\/PIWTJWFjj6ppGgiDbtAmLxQcqHajKnUf8fpx6qSNEmFzpC8uCrhPaJF\\\\\\\\\\\\\\\/OZw8Lu0VhrarKAOncPa2uiZ0cUVgH2n\\\\\\\\\\\\\\\/z8oFCzr4ZYWeiRrlOoiTPVfGMdFXQ8fjhMjWMd842dqiE8+g\\\\\\\\\\\\\\\/Eyo2sZx9fuikDbpnux2ojHZJ\\\\\\\\\\\\\\\/083itvlQPEVJKaIYCzehcPzQW0dAhhNb08StoNiGr4YKIspxZ8sqqzmJRGDmNGlzfv1hWBdAUfsEaSQbM8o=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022IGDs6TwXl0\\\\\\\\\\\\\\\/GZGmEJIxSdA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022cfeb6e4375de8a85f4ddf77d2cce03ecf888d8251e031298045460daf4c7a06b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/1\\\/e000395.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/1\\\/e000395.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2019-000395\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2019-000395\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2019-000395\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}